(20 nodes) Positive regulation of triglyceride biosynthetic process network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	Gpld1	Phosphatidylinositol-glycan-specific phospholipase D. (778 aa)
	LDLR	Low-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family. (862 aa)
	Tcf7l2	Transcription factor 7-like 1. (73 aa)
	Kat5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
	I79_020783	Transcription factor 7-like 2. (451 aa)
	I79_020697	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (980 aa)
	Apoc3	Apolipoprotein C-III. (76 aa)
	Nr1h2	Oxysterols receptor LXR-beta. (445 aa)
	Scarb1	Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
	Dgat1	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family. (327 aa)
	I79_015046	Low-density lipoprotein receptor. (160 aa)
	Dgat2	Diacylglycerol O-acyltransferase 2. (388 aa)
	I79_012422	Long-chain-fatty-acid--CoA ligase 5. (171 aa)
	Mfsd2a	Major facilitator superfamily domain-containing protein 2. (527 aa)
	I79_010155	Sterol regulatory element-binding protein 1. (1050 aa)
	I79_008173	Perilipin; Belongs to the perilipin family. (419 aa)
	Slc27a1	Long-chain fatty acid transport protein 1. (218 aa)
	Rgn	Regucalcin. (265 aa)
	Nr1h3	Oxysterols receptor LXR-alpha. (402 aa)
	Ctdnep1	Serine/threonine-protein phosphatase dullard. (210 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Apoc3	Scarb1	G3I7Q2	G3HX53	Apolipoprotein C-III.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.548
Dgat1	Dgat2	G3HWM3	G3HUS2	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	Diacylglycerol O-acyltransferase 2.	0.995
Dgat1	I79_010155	G3HWM3	G3HHP9	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	Sterol regulatory element-binding protein 1.	0.506
Dgat1	I79_012422	G3HWM3	G3HNS8	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	Long-chain-fatty-acid--CoA ligase 5.	0.469
Dgat1	I79_020697	G3HWM3	G3IAR7	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	Glycerol-3-phosphate acyltransferase 1, mitochondrial.	0.414
Dgat1	Scarb1	G3HWM3	G3HX53	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.472
Dgat1	Slc27a1	G3HWM3	G3H4D5	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	Long-chain fatty acid transport protein 1.	0.413
Dgat2	Dgat1	G3HUS2	G3HWM3	Diacylglycerol O-acyltransferase 2.	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	0.995
Dgat2	I79_010155	G3HUS2	G3HHP9	Diacylglycerol O-acyltransferase 2.	Sterol regulatory element-binding protein 1.	0.494
Dgat2	I79_012422	G3HUS2	G3HNS8	Diacylglycerol O-acyltransferase 2.	Long-chain-fatty-acid--CoA ligase 5.	0.472
Dgat2	Slc27a1	G3HUS2	G3H4D5	Diacylglycerol O-acyltransferase 2.	Long-chain fatty acid transport protein 1.	0.681
I79_008173	Scarb1	G3HCG3	G3HX53	Perilipin; Belongs to the perilipin family.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.412
I79_010155	Dgat1	G3HHP9	G3HWM3	Sterol regulatory element-binding protein 1.	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	0.506
I79_010155	Dgat2	G3HHP9	G3HUS2	Sterol regulatory element-binding protein 1.	Diacylglycerol O-acyltransferase 2.	0.494
I79_010155	I79_020697	G3HHP9	G3IAR7	Sterol regulatory element-binding protein 1.	Glycerol-3-phosphate acyltransferase 1, mitochondrial.	0.424
I79_010155	Nr1h2	G3HHP9	G3I731	Sterol regulatory element-binding protein 1.	Oxysterols receptor LXR-beta.	0.605
I79_010155	Nr1h3	G3HHP9	G3GYK3	Sterol regulatory element-binding protein 1.	Oxysterols receptor LXR-alpha.	0.694
I79_012422	Dgat1	G3HNS8	G3HWM3	Long-chain-fatty-acid--CoA ligase 5.	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	0.469
I79_012422	Dgat2	G3HNS8	G3HUS2	Long-chain-fatty-acid--CoA ligase 5.	Diacylglycerol O-acyltransferase 2.	0.472
I79_012422	Slc27a1	G3HNS8	G3H4D5	Long-chain-fatty-acid--CoA ligase 5.	Long-chain fatty acid transport protein 1.	0.484