(32 nodes) Positive regulation of cholesterol efflux network (Cricetulus griseus)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	Abca3	ATP-binding cassette sub-family A member 3. (1704 aa)
	I79_019626	Liver carboxylesterase 4. (105 aa)
	I79_008639	NF-kappa-B inhibitor alpha. (52 aa)
	I79_019625	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (514 aa)
	Apoa1	Apolipoprotein A-I. (264 aa)
	Nr1h2	Oxysterols receptor LXR-beta. (445 aa)
	I79_018763	Liver carboxylesterase 4. (393 aa)
	I79_018762	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (370 aa)
	I79_018761	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (448 aa)
	Nfkbia	NF-kappa-B inhibitor alpha. (224 aa)
	I79_017374	ATP-binding cassette sub-family A member 12. (506 aa)
	Adipoq	Adiponectin. (248 aa)
	Lrp1	Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
	I79_015031	ATP-binding cassette sub-family A member 12. (892 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
	Eepd1	Endonuclease/exonuclease/phosphatase family domain-containing protein 1. (569 aa)
	Pon1	Serum paraoxonase/arylesterase 1. (355 aa)
	Apoe	Apolipoprotein E. (313 aa)
	Abcg1	ATP-binding cassette sub-family G member 1. (647 aa)
	I79_010458	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (451 aa)
	Abca7	ATP-binding cassette sub-family A member 7. (408 aa)
	Zdhhc8	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (742 aa)
	I79_008640	NF-kappa-B inhibitor alpha. (90 aa)
	Sirt1	NAD-dependent deacetylase sirtuin-1. (554 aa)
	Nr1h3	Oxysterols receptor LXR-alpha. (402 aa)
	Pltp	Phospholipid transfer protein. (493 aa)
	Cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
	Abca1	ATP-binding cassette sub-family A member 1. (2261 aa)
	Gps2	G protein pathway suppressor 2. (327 aa)
	Ptch1	Protein patched-like 1. (1114 aa)
	I79_019630	Liver carboxylesterase 1; Belongs to the type-B carboxylesterase/lipase family. (765 aa)
	I79_019629	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (564 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abca1	Abcg1	G3GTZ6	G3HLD6	ATP-binding cassette sub-family A member 1.	ATP-binding cassette sub-family G member 1.	0.500
Abca1	Apoa1	G3GTZ6	G3I7Q1	ATP-binding cassette sub-family A member 1.	Apolipoprotein A-I.	0.945
Abca1	Apoe	G3GTZ6	G3HPC9	ATP-binding cassette sub-family A member 1.	Apolipoprotein E.	0.882
Abca1	Cav1	G3GTZ6	G3H9I8	ATP-binding cassette sub-family A member 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.649
Abca1	Nr1h2	G3GTZ6	G3I731	ATP-binding cassette sub-family A member 1.	Oxysterols receptor LXR-beta.	0.863
Abca1	Nr1h3	G3GTZ6	G3GYK3	ATP-binding cassette sub-family A member 1.	Oxysterols receptor LXR-alpha.	0.891
Abca1	PPARG	G3GTZ6	G3HVG0	ATP-binding cassette sub-family A member 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.693
Abca1	Pltp	G3GTZ6	G3H8V4	ATP-binding cassette sub-family A member 1.	Phospholipid transfer protein.	0.722
Abca1	Pon1	G3GTZ6	G3HT85	ATP-binding cassette sub-family A member 1.	Serum paraoxonase/arylesterase 1.	0.429
Abca1	Zdhhc8	G3GTZ6	G3HEQ5	ATP-binding cassette sub-family A member 1.	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	0.498
Abca7	Apoe	G3HF57	G3HPC9	ATP-binding cassette sub-family A member 7.	Apolipoprotein E.	0.414
Abca7	I79_017374	G3HF57	G3I1V5	ATP-binding cassette sub-family A member 7.	ATP-binding cassette sub-family A member 12.	0.692
Abcg1	Abca1	G3HLD6	G3GTZ6	ATP-binding cassette sub-family G member 1.	ATP-binding cassette sub-family A member 1.	0.500
Abcg1	Apoe	G3HLD6	G3HPC9	ATP-binding cassette sub-family G member 1.	Apolipoprotein E.	0.816
Abcg1	Nr1h2	G3HLD6	G3I731	ATP-binding cassette sub-family G member 1.	Oxysterols receptor LXR-beta.	0.632
Abcg1	Nr1h3	G3HLD6	G3GYK3	ATP-binding cassette sub-family G member 1.	Oxysterols receptor LXR-alpha.	0.702
Abcg1	PPARG	G3HLD6	G3HVG0	ATP-binding cassette sub-family G member 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.574
Abcg1	Pltp	G3HLD6	G3H8V4	ATP-binding cassette sub-family G member 1.	Phospholipid transfer protein.	0.732
Adipoq	Apoe	G3HYG0	G3HPC9	Adiponectin.	Apolipoprotein E.	0.590
Adipoq	PPARG	G3HYG0	G3HVG0	Adiponectin.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.885