STRINGSTRING
Plin2 Plin2 I79_000648 I79_000648 Lpl Lpl I79_006938 I79_006938 I79_008173 I79_008173 Plin3 Plin3 Fitm1 Fitm1 I79_012640 I79_012640 I79_014015 I79_014015 PPARG PPARG Fitm2 Fitm2 Pnpla2 Pnpla2 I79_022390 I79_022390 Ppara Ppara
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Plin2Perilipin; Belongs to the perilipin family. (432 aa)
I79_000648Oxysterol-binding protein; Belongs to the OSBP family. (989 aa)
LplLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (450 aa)
I79_0069381-acylglycerol-3-phosphate O-acyltransferase ABHD5. (322 aa)
I79_008173Perilipin; Belongs to the perilipin family. (419 aa)
Plin3Perilipin; Belongs to the perilipin family. (440 aa)
Fitm1Fat storage-inducing transmembrane protein 1. (287 aa)
I79_012640Apolipoprotein C-IV. (158 aa)
I79_014015Oxysterol-binding protein; Belongs to the OSBP family. (472 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Fitm2Fat storage-inducing transmembrane protein 2. (262 aa)
Pnpla2Patatin-like phospholipase domain-containing protein 2. (486 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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