STRINGSTRING
Irs1 Irs1 Wdr5 Wdr5 I79_020783 I79_020783 I79_020647 I79_020647 Sik1 Sik1 I79_019839 I79_019839 Bckdk Bckdk Igfbp4 Igfbp4 Ep300 Ep300 Actn3 Actn3 I79_018194 I79_018194 C1qtnf12 C1qtnf12 Ppp4r3a Ppp4r3a Serpina12 Serpina12 Erfe Erfe Nnmt Nnmt Hnf4a Hnf4a Pth Pth Foxo1 Foxo1 Hif1a Hif1a Adipoq Adipoq I79_015980 I79_015980 I79_015916 I79_015916 I79_015895 I79_015895 Foxa2 Foxa2 Insr Insr Gpt Gpt I79_015109 I79_015109 Dgat2 Dgat2 Dusp12 Dusp12 Epm2aip1 Epm2aip1 Pdk4 Pdk4 I79_014111 I79_014111 I79_013329 I79_013329 I79_013328 I79_013328 Pdk3 Pdk3 I79_012722 I79_012722 Cry1 Cry1 Akt2 Akt2 Gck Gck Kat2a Kat2a C1qtnf3 C1qtnf3 Ppp4r3b Ppp4r3b Pdk2 Pdk2 Ranbp2 Ranbp2 I79_010352 I79_010352 I79_009443 I79_009443 Midn Midn Stk11 Stk11 Nr3c1 Nr3c1 Dgkq Dgkq C1qtnf2 C1qtnf2 Gpld1 Gpld1 Zmpste24 Zmpste24 Clk2 Clk2 I79_007993 I79_007993 Pgp Pgp Sirt1 Sirt1 Mst1 Mst1 I79_006650 I79_006650 Pfkfb1 Pfkfb1 Igf1 Igf1 Nfe2l1 Nfe2l1 Nln Nln Rgn Rgn Adipor1 Adipor1 I79_004757 I79_004757 Akt1 Akt1 I79_004236 I79_004236 Sesn2 Sesn2 I79_003945 I79_003945 Pfkfb2 Pfkfb2 Lep Lep Dyrk2 Dyrk2 Src Src Soga1 Soga1 Foxk2 Foxk2 I79_002406 I79_002406 I79_002020 I79_002020 Acadm Acadm Usp7 Usp7 Gnb3 Gnb3 Tigar Tigar Pdk1 Pdk1 Slc25a12 Slc25a12 Mlycd Mlycd CgPICR_005189 CgPICR_005189 slc25B4 slc25B4 I79_025689 I79_025689 C1qtnf6 C1qtnf6 I79_024892 I79_024892 Arpp19 Arpp19 Irs2 Irs2 Tcf7l2 Tcf7l2 Ddb1 Ddb1 Lcmt1 Lcmt1 Znf692 Znf692 Rora Rora Ppara Ppara I79_022390 I79_022390 I79_022343 I79_022343 I79_021840 I79_021840 Fam3c Fam3c
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Irs1Insulin receptor substrate 1. (1233 aa)
Wdr5WD repeat-containing protein 5. (334 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
I79_020647Protein FAM48A. (330 aa)
Sik1Serine/threonine-protein kinase SIK1. (729 aa)
I79_019839Nuclear receptor coactivator. (1413 aa)
BckdkProtein-serine/threonine kinase. (412 aa)
Igfbp4Insulin-like growth factor-binding protein 4. (254 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
Actn3Alpha-actinin-3. (900 aa)
I79_018194Protein FAM132A. (127 aa)
C1qtnf12Protein FAM132A. (61 aa)
Ppp4r3aSerine/threonine-protein phosphatase 4 regulatory subunit 3A. (400 aa)
Serpina12Serpin A12; Belongs to the serpin family. (414 aa)
ErfeProtein FAM132B. (344 aa)
NnmtNicotinamide N-methyltransferase. (265 aa)
Hnf4aHepatocyte nuclear factor 4-alpha. (464 aa)
PthParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)
Foxo1Forkhead box protein O1. (469 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
AdipoqAdiponectin. (248 aa)
I79_015980Leptin receptor. (533 aa)
I79_015916Insulin-like growth factor II. (155 aa)
I79_015895Sorbin and SH3 domain-containing protein 1. (852 aa)
Foxa2Hepatocyte nuclear factor 3-beta. (430 aa)
InsrInsulin receptor. (114 aa)
GptAlanine aminotransferase 1. (481 aa)
I79_015109Interleukin-6. (174 aa)
Dgat2Diacylglycerol O-acyltransferase 2. (388 aa)
Dusp12Dual specificity protein phosphatase 12. (291 aa)
Epm2aip1EPM2A-interacting protein 1. (606 aa)
Pdk4Protein-serine/threonine kinase. (178 aa)
I79_014111Protein-serine/threonine kinase. (60 aa)
I79_013329Glycine N-methyltransferase. (69 aa)
I79_013328Glycine N-methyltransferase. (71 aa)
Pdk3Protein-serine/threonine kinase. (415 aa)
I79_012722Major urinary protein 5; Belongs to the calycin superfamily. Lipocalin family. (153 aa)
Cry1Cryptochrome-1. (428 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
GckPhosphotransferase. (465 aa)
Kat2aHistone acetyltransferase KAT2A. (663 aa)
C1qtnf3Complement C1q tumor necrosis factor-related protein 3. (319 aa)
Ppp4r3bSerine/threonine-protein phosphatase 4 regulatory subunit 3B. (1364 aa)
Pdk2Protein-serine/threonine kinase. (407 aa)
Ranbp2E3 SUMO-protein ligase RanBP2. (3068 aa)
I79_010352Acetyl-CoA carboxylase 2. (2287 aa)
I79_009443Steroid hormone receptor ERR2. (475 aa)
MidnMidnolin. (317 aa)
Stk11Serine/threonine-protein kinase 11. (505 aa)
Nr3c1Glucocorticoid receptor. (748 aa)
DgkqDiacylglycerol kinase. (491 aa)
C1qtnf2Complement C1q tumor necrosis factor-related protein 2. (285 aa)
Gpld1Phosphatidylinositol-glycan-specific phospholipase D. (778 aa)
Zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
Clk2Dual specificity protein kinase CLK2. (109 aa)
I79_007993Dual specificity protein kinase CLK2. (137 aa)
PgpPhosphoglycolate phosphatase. (617 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
Mst1Hepatocyte growth factor-like protein. (88 aa)
I79_006650Hepatocyte growth factor-like protein. (93 aa)
Pfkfb16-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1-like isoform 1. (448 aa)
Igf1Insulin-like growth factor I. (75 aa)
Nfe2l1Nuclear factor erythroid 2-related factor 1. (740 aa)
NlnNeurolysin, mitochondrial. (704 aa)
RgnRegucalcin. (265 aa)
Adipor1Adiponectin receptor protein 1. (375 aa)
I79_004757Complement C1q tumor necrosis factor-related protein 1. (314 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
I79_004236Protein-serine/threonine kinase. (49 aa)
Sesn2Sestrin-2. (480 aa)
I79_003945Cytochrome c oxidase assembly protein COX11, mitochondrial. (142 aa)
Pfkfb26-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2. (784 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Dyrk2Dual specificity tyrosine-phosphorylation-regulated kinase 2. (528 aa)
SrcTyrosine-protein kinase. (536 aa)
Soga1Uncharacterized protein C20orf117. (1897 aa)
Foxk2Forkhead box protein K2. (448 aa)
I79_002406NAD-dependent deacetylase sirtuin-7. (306 aa)
I79_002020Glucokinase regulatory protein. (583 aa)
AcadmMedium-chain specific acyl-CoA dehydrogenase, mitochondrial. (96 aa)
Usp7Ubiquitin carboxyl-terminal hydrolase 7. (82 aa)
Gnb3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (227 aa)
TigarPutative fructose-2,6-bisphosphatase TIGAR. (266 aa)
Pdk1Protein-serine/threonine kinase. (344 aa)
Slc25a12Calcium-binding mitochondrial carrier protein Aralar1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (646 aa)
MlycdMalonyl-CoA decarboxylase, mitochondrial. (190 aa)
CgPICR_005189cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (96 aa)
slc25B4UDP-xylose and UDP-N-acetylglucosamine transporter. (331 aa)
I79_025689Epididymal-specific lipocalin-13; Belongs to the calycin superfamily. Lipocalin family. (158 aa)
C1qtnf6Complement C1q tumor necrosis factor-related protein 6. (266 aa)
I79_024892Fructose-1,6-bisphosphatase 1. (66 aa)
Arpp19cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (112 aa)
Irs2Insulin receptor substrate 2. (465 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
Ddb1DNA damage-binding protein 1. (1140 aa)
Lcmt1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (328 aa)
Znf692Zinc finger protein 692. (222 aa)
RoraNuclear receptor ROR-alpha. (959 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
I79_022343UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1444 aa)
I79_021840Nuclear receptor ROR-gamma. (341 aa)
Fam3cProtein FAM3C. (227 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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