STRINGSTRING
Vegfc Vegfc Myc Myc Egr2 Egr2 Serpine2 Serpine2 Tnfrsf1b Tnfrsf1b CgPICR_008504 CgPICR_008504 I79_023241 I79_023241 I79_022486 I79_022486 Mtor Mtor I79_021945 I79_021945 Rela Rela Spint1 Spint1 I79_020615 I79_020615 Tgfb1 Tgfb1 Ptk2 Ptk2 I79_019031 I79_019031 I79_018913 I79_018913 Sox10 Sox10 Il33 Il33 Clcf1 Clcf1 Acy3 Acy3 I79_017561 I79_017561 Lyn Lyn IL1B IL1B Lif Lif Lta Lta Tnf Tnf Dicer1 Dicer1 Prkch Prkch Tspo Tspo I79_015503 I79_015503 I79_015109 I79_015109 PPARG PPARG I79_014451 I79_014451 Prmt5 Prmt5 Ptprz1 Ptprz1 I79_011789 I79_011789 Gfap Gfap Bin1 Bin1 Rtn4 Rtn4 I79_010923 I79_010923 Znf365 Znf365 Prkci Prkci Il6st Il6st Hdac2 Hdac2 I79_008941 I79_008941 Sox8 Sox8 Rheb Rheb E2f1 E2f1 Il34 Il34 I79_007340 I79_007340 I79_007329 I79_007329 I79_007328 I79_007328 Ptn Ptn I79_006924 I79_006924 I79_006923 I79_006923 Hdac1 Hdac1 Dag1 Dag1 I79_006225 I79_006225 Igf1 Igf1 Ptpra Ptpra Hvcn1 Hvcn1 Nog Nog Cxcr4 Cxcr4 I79_003225 I79_003225 Actr3 Actr3 Mdk Mdk I79_002693 I79_002693 I79_002099 I79_002099 I79_001731 I79_001731 Ntf3 Ntf3 Atxn1 Atxn1 I79_001239 I79_001239 Synj1 Synj1 I79_000801 I79_000801 Slc7a5 Slc7a5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa)
MycMyc proto-oncogene protein. (281 aa)
Egr2Early growth response protein 2. (410 aa)
Serpine2Glia-derived nexin; Belongs to the serpin family. (189 aa)
Tnfrsf1bTumor necrosis factor receptor superfamily member 1B. (477 aa)
CgPICR_008504Serine/threonine-protein phosphatase PP1-alpha catalytic subunit-like protein. (326 aa)
I79_023241Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (558 aa)
I79_022486GS homeobox 2. (100 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
I79_021945Pre-mRNA-processing factor 19. (487 aa)
RelaTranscription factor p65. (546 aa)
Spint1Kunitz-type protease inhibitor 1. (499 aa)
I79_020615BAG family molecular chaperone regulator 1. (125 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1027 aa)
I79_019031Teneurin-4. (3477 aa)
I79_018913Homeobox protein Nkx-6.2. (114 aa)
Sox10Transcription factor SOX-10. (466 aa)
Il33Interleukin-33. (217 aa)
Clcf1Cardiotrophin-like cytokine factor 1. (225 aa)
Acy3Aspartoacylase-2. (319 aa)
I79_017561Tyrosine-protein kinase Lyn. (101 aa)
LynTyrosine-protein kinase. (289 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
LifLeukemia inhibitory factor-like protein. (158 aa)
LtaLymphotoxin-alpha; Belongs to the tumor necrosis factor family. (202 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
Dicer1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
PrkchProtein kinase C eta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (635 aa)
TspoTranslocator protein. (169 aa)
I79_015503Transcription factor HES-1. (92 aa)
I79_015109Interleukin-6. (174 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
I79_014451Pro-neuregulin-1, membrane-bound isoform. (639 aa)
Prmt5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (577 aa)
Ptprz1Receptor-type tyrosine-protein phosphatase zeta. (2289 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
GfapGlial fibrillary acidic protein; Belongs to the intermediate filament family. (427 aa)
Bin1Myc box-dependent-interacting protein 1. (522 aa)
Rtn4Reticulon-4. (806 aa)
I79_010923Reticulon. (68 aa)
Znf365Protein ZNF365. (313 aa)
PrkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (560 aa)
Il6stInterleukin-6 receptor subunit beta. (914 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
Sox8Transcription factor SOX-8. (463 aa)
RhebGTP-binding protein Rheb. (179 aa)
E2f1Transcription factor E2F1. (367 aa)
Il34Interleukin-34. (201 aa)
I79_007340Ectonucleotide pyrophosphatase/phosphodiesterase family member 2. (592 aa)
I79_007329Histone deacetylase 1. (250 aa)
I79_007328Histone deacetylase 2. (91 aa)
PtnPleiotrophin. (168 aa)
I79_006924Histone deacetylase 1. (188 aa)
I79_006923Histone deacetylase 1. (235 aa)
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
Dag1Dystroglycan. (893 aa)
I79_006225Sonic hedgehog protein. (226 aa)
Igf1Insulin-like growth factor I. (75 aa)
PtpraReceptor-type tyrosine-protein phosphatase alpha. (1074 aa)
Hvcn1Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (511 aa)
NogNoggin. (117 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (290 aa)
I79_003225Serotransferrin. (1227 aa)
Actr3Actin-related protein 3; Belongs to the actin family. (418 aa)
MdkMidkine. (160 aa)
I79_002693Netrin-1. (252 aa)
I79_002099Vascular endothelial growth factor receptor 1. (115 aa)
I79_001731RING finger protein 112. (443 aa)
Ntf3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (258 aa)
Atxn1Ataxin-1. (790 aa)
I79_001239Low-density lipoprotein receptor-related protein 2. (4664 aa)
Synj1Synaptojanin-1. (600 aa)
I79_000801Histone deacetylase 1. (92 aa)
Slc7a5Large neutral amino acids transporter small subunit 1. (506 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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