STRINGSTRING
I79_013214 I79_013214 Fbxo32 Fbxo32 I79_022161 I79_022161 Actn3 Actn3 Trim63 Trim63 Pik3ca Pik3ca Dmd Dmd Hdac4 Hdac4 Sgca Sgca Il10 Il10 Dag1 Dag1 Myog Myog I79_004403 I79_004403 Drd2 Drd2 Cat Cat
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_013214Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1929 aa)
Fbxo32F-box only protein 32. (101 aa)
I79_022161Dystrophin. (655 aa)
Actn3Alpha-actinin-3. (900 aa)
Trim63E3 ubiquitin-protein ligase TRIM63. (355 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (86 aa)
DmdDystrophin. (617 aa)
Hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (966 aa)
SgcaAlpha-sarcoglycan. (127 aa)
Il10Interleukin-10. (178 aa)
Dag1Dystroglycan. (893 aa)
MyogMyogenin. (224 aa)
I79_004403D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
Drd2D(2) dopamine receptor. (274 aa)
CatCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (555 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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