(17 nodes) Regulation of skeletal muscle cell proliferation network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Sirt1	NAD-dependent deacetylase sirtuin-1. (554 aa)
	Paxbp1	GC-rich sequence DNA-binding factor-like. (178 aa)
	Cav2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	I79_006225	Sonic hedgehog protein. (226 aa)
	Myog	Myogenin. (224 aa)
	Mstn	Growth/differentiation factor 8. (295 aa)
	Jak2	Tyrosine-protein kinase. (1122 aa)
	Six1	Homeobox protein SIX1. (284 aa)
	I79_021283	Angiopoietin-1. (298 aa)
	Selenon	Selenoprotein N. (343 aa)
	Cflar	CASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (484 aa)
	Ppard	Peroxisome proliferator-activated receptor delta. (440 aa)
	Stat3	Signal transducer and activator of transcription. (770 aa)
	Ephb1	Ephrin type-B receptor 1. (737 aa)
	I79_007548	Angiopoietin-1. (112 aa)
	I79_000818	GC-rich sequence DNA-binding factor-like. (63 aa)
	I79_000817	GC-rich sequence DNA-binding factor-like. (83 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I79_000817	Paxbp1	G3GT43	G3GT42	GC-rich sequence DNA-binding factor-like.	GC-rich sequence DNA-binding factor-like.	0.940
Jak2	Stat3	G3IEQ4	G3HLW9	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.999
Mstn	Myog	G3IJ34	G3H3L0	Growth/differentiation factor 8.	Myogenin.	0.591
Myog	Mstn	G3H3L0	G3IJ34	Myogenin.	Growth/differentiation factor 8.	0.591
Myog	Six1	G3H3L0	G3IE65	Myogenin.	Homeobox protein SIX1.	0.524
Paxbp1	I79_000817	G3GT42	G3GT43	GC-rich sequence DNA-binding factor-like.	GC-rich sequence DNA-binding factor-like.	0.940
Sirt1	Stat3	G3HAB1	G3HLW9	NAD-dependent deacetylase sirtuin-1.	Signal transducer and activator of transcription.	0.575
Six1	Myog	G3IE65	G3H3L0	Homeobox protein SIX1.	Myogenin.	0.524
Stat3	Jak2	G3HLW9	G3IEQ4	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.999
Stat3	Sirt1	G3HLW9	G3HAB1	Signal transducer and activator of transcription.	NAD-dependent deacetylase sirtuin-1.	0.575