(67 nodes) SCF ubiquitin ligase complex network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Fbxl16	F-box/LRR-repeat protein 16. (488 aa)
	I79_008017	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (80 aa)
	Fbxo7	F-box only protein 7. (381 aa)
	Fbxo4	F-box only protein 4. (248 aa)
	Cks2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (57 aa)
	Fbxl4	F-box/LRR-repeat protein 4. (158 aa)
	I79_010631	F-box/LRR-repeat protein 21. (409 aa)
	H671_3g8974	F-box/WD repeat-containing protein 11. (122 aa)
	I79_010766	F-box only protein 17. (110 aa)
	I79_010767	F-box only protein 27. (156 aa)
	Nccrp1	Non-specific cytotoxic cell receptor protein 1-like. (196 aa)
	Skp2	S-phase kinase-associated protein 2. (424 aa)
	Amn1	Protein AMN1-like. (215 aa)
	I79_012914	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (80 aa)
	I79_013004	F-box/WD repeat-containing protein 7. (709 aa)
	I79_013734	F-box only protein 39. (443 aa)
	Cul2	Cullin-2; Belongs to the cullin family. (745 aa)
	Fbxo2	F-box only protein 2. (332 aa)
	CgPICR_017870	F-box only protein 44-like isoform 1. (255 aa)
	I79_014633	F-box only protein 6. (159 aa)
	I79_014634	F-box only protein 6. (197 aa)
	Usp47	Ubiquitin carboxyl-terminal hydrolase 47. (754 aa)
	Fbxl6	F-box/LRR-repeat protein 6. (334 aa)
	I79_015880	F-box only protein 37. (399 aa)
	Fbxl13	F-box/LRR-repeat protein 13. (245 aa)
	Fbxl7	F-box/LRR-repeat protein 7. (444 aa)
	Fbxl8	F-box/LRR-repeat protein 8. (374 aa)
	I79_026250	F-box only protein 33. (76 aa)
	Fbh1	F-box only protein 18. (580 aa)
	I79_000037	F-box/WD repeat-containing protein 11. (481 aa)
	I79_000250	F-box only protein 31. (436 aa)
	Gse1	Genetic suppressor element 1. (1195 aa)
	I79_000261	Uncharacterized protein. (382 aa)
	I79_000746	SPRY domain-containing SOCS box protein 4. (220 aa)
	Spsb4	SPRY domain-containing SOCS box protein 4. (63 aa)
	Spsb2	SPRY domain-containing SOCS box protein 2. (264 aa)
	Fbxl18	F-box/LRR-repeat protein 18. (715 aa)
	Cul1	Cullin-1; Belongs to the cullin family. (776 aa)
	Cacybp	Calcyclin-binding protein. (184 aa)
	Fbxo25	F-box only protein 25. (357 aa)
	Skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	Crtap	F-box/LRR-repeat protein 2. (539 aa)
	Tmem183a	Transmembrane protein 183. (376 aa)
	Fbxl22	F-box/LRR-repeat protein 22. (112 aa)
	I79_005417	F-box/LRR-repeat protein 17. (51 aa)
	Fbxo32	F-box only protein 32. (101 aa)
	Trim21	52 kDa Ro protein. (463 aa)
	I79_024364	WD repeat-containing protein 69. (106 aa)
	Fbxw5	F-box/WD repeat-containing protein 5. (569 aa)
	Fbxl5	F-box/LRR-repeat protein 5. (554 aa)
	I79_022404	WD repeat-containing protein 69. (253 aa)
	I79_021142	F-box only protein 15. (113 aa)
	Fbxo42	F-box only protein 42. (624 aa)
	Fbxo33	F-box only protein 33. (394 aa)
	Spsb1	SPRY domain-containing SOCS box protein 1. (273 aa)
	H671_3g9909	F-box/LRR-repeat protein 19. (593 aa)
	Pnkp	Bifunctional polynucleotide phosphatase/kinase. (522 aa)
	Fbxo9	F-box only protein 9. (366 aa)
	Fbxw4	F-box/WD repeat-containing protein 4. (292 aa)
	Btrc	F-box/WD repeat-containing protein 1A. (488 aa)
	Cul5	Cullin-5; Belongs to the cullin family. (780 aa)
	Lrrc29	Leucine-rich repeat-containing protein 29. (210 aa)
	Fbxl17	F-box/LRR-repeat protein 17. (165 aa)
	I79_005715	F-box/LRR-repeat protein 20. (308 aa)
	Fbxl12	F-box/LRR-repeat protein 12. (326 aa)
	Spsb3	SPRY domain-containing SOCS box protein 3. (354 aa)
	I79_008016	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (57 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Amn1	Cul1	G3HPG4	G3GXG0	Protein AMN1-like.	Cullin-1; Belongs to the cullin family.	0.491
Amn1	Skp1	G3HPG4	G3H2C9	Protein AMN1-like.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.707
Btrc	Cul1	G3I574	G3GXG0	F-box/WD repeat-containing protein 1A.	Cullin-1; Belongs to the cullin family.	0.999
Btrc	Fbxo2	G3I574	G3HUL8	F-box/WD repeat-containing protein 1A.	F-box only protein 2.	0.945
Btrc	Fbxo4	G3I574	G3HHE8	F-box/WD repeat-containing protein 1A.	F-box only protein 4.	0.915
Btrc	Fbxw4	G3I574	G3I579	F-box/WD repeat-containing protein 1A.	F-box/WD repeat-containing protein 4.	0.414
Btrc	H671_3g8974	G3I574	G3HJ61	F-box/WD repeat-containing protein 1A.	F-box/WD repeat-containing protein 11.	0.640
Btrc	I79_000037	G3I574	G3GR94	F-box/WD repeat-containing protein 1A.	F-box/WD repeat-containing protein 11.	0.639
Btrc	I79_013004	G3I574	G3HQA7	F-box/WD repeat-containing protein 1A.	F-box/WD repeat-containing protein 7.	0.559
Btrc	Skp1	G3I574	G3H2C9	F-box/WD repeat-containing protein 1A.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.999
Btrc	Skp2	G3I574	G3HJU6	F-box/WD repeat-containing protein 1A.	S-phase kinase-associated protein 2.	0.965
Btrc	Usp47	G3I574	G3HWE6	F-box/WD repeat-containing protein 1A.	Ubiquitin carboxyl-terminal hydrolase 47.	0.560
Cacybp	Skp1	G3GZL7	G3H2C9	Calcyclin-binding protein.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.989
CgPICR_017870	Cul1	G3HUL9	G3GXG0	F-box only protein 44-like isoform 1.	Cullin-1; Belongs to the cullin family.	0.686
CgPICR_017870	Skp1	G3HUL9	G3H2C9	F-box only protein 44-like isoform 1.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.790
Cks2	Cul1	G3HIB0	G3GXG0	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cullin-1; Belongs to the cullin family.	0.972
Cks2	I79_008016	G3HIB0	G3HC66	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.591
Cks2	I79_008017	G3HIB0	G3HC67	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.957
Cks2	I79_012914	G3HIB0	G3HQ25	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.957
Cks2	Skp1	G3HIB0	G3H2C9	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.980