(32 nodes) NAD metabolic process network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	Pfkp	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (793 aa)
	I79_023874	Pyruvate kinase; Belongs to the pyruvate kinase family. (233 aa)
	Pfkm	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	I79_020755	Pyruvate kinase; Belongs to the pyruvate kinase family. (461 aa)
	I79_020424	Pyruvate kinase; Belongs to the pyruvate kinase family. (258 aa)
	I79_017480	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (382 aa)
	Nadk	NAD kinase. (445 aa)
	Nqo1	NAD(P)H dehydrogenase [quinone] 1. (274 aa)
	I79_016125	Pyruvate kinase isozymes M1/M2. (110 aa)
	Gpd1	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (443 aa)
	I79_014006	L-lactate dehydrogenase A chain. (84 aa)
	I79_014005	L-lactate dehydrogenase A chain. (119 aa)
	Nmrk2	Nicotinamide riboside kinase 2. (177 aa)
	I79_013031	L-lactate dehydrogenase A chain. (94 aa)
	I79_012728	L-lactate dehydrogenase A chain. (137 aa)
	Pgam2	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
	Aldob	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	Ranbp3l	UPF0465 protein C5orf33-like. (275 aa)
	Ldhb	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
	I79_009741	L-lactate dehydrogenase A chain. (112 aa)
	Mdh1	Malate dehydrogenase. (334 aa)
	Pck2	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (640 aa)
	I79_007738	Pyruvate kinase isozymes M1/M2. (120 aa)
	CgPICR_019784	Glycerol-3-phosphate dehydrogenase 1-like protein. (133 aa)
	Pfkl	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (745 aa)
	Hk1	Hexokinase-1. (917 aa)
	Pkm	Pyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
	I79_003584	L-lactate dehydrogenase A chain; Belongs to the LDH/MDH superfamily. (156 aa)
	Eno3	Beta-enolase. (270 aa)
	Foxk2	Forkhead box protein K2. (448 aa)
	Gpd1l	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (312 aa)
	Eno2	Gamma-enolase. (434 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aldob	Eno2	G3HJY5	G3GUQ0	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Gamma-enolase.	0.866
Aldob	Eno3	G3HJY5	G3GYC7	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Beta-enolase.	0.891
Aldob	Hk1	G3HJY5	G3H6T5	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Hexokinase-1.	0.831
Aldob	Ldhb	G3HJY5	G3HH14	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.847
Aldob	Pck2	G3HJY5	G3HDE8	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial.	0.527
Aldob	Pfkl	G3HJY5	G3H8W5	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.	0.971
Aldob	Pfkm	G3HJY5	G3IDJ8	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.957
Aldob	Pfkp	G3HJY5	G3GR86	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.957
Aldob	Pgam2	G3HJY5	G3HM99	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.875
Aldob	Pkm	G3HJY5	G3H3Q1	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.888
CgPICR_019784	Gpd1	G3HB59	G3HX67	Glycerol-3-phosphate dehydrogenase 1-like protein.	Glycerol-3-phosphate dehydrogenase [NAD(+)].	0.930
CgPICR_019784	Gpd1l	G3HB59	G3GV81	Glycerol-3-phosphate dehydrogenase 1-like protein.	Glycerol-3-phosphate dehydrogenase [NAD(+)].	0.901
CgPICR_019784	Mdh1	G3HB59	G3HDQ2	Glycerol-3-phosphate dehydrogenase 1-like protein.	Malate dehydrogenase.	0.406
CgPICR_019784	Nadk	G3HB59	G3I1X7	Glycerol-3-phosphate dehydrogenase 1-like protein.	NAD kinase.	0.771
Eno2	Aldob	G3GUQ0	G3HJY5	Gamma-enolase.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.866
Eno2	Eno3	G3GUQ0	G3GYC7	Gamma-enolase.	Beta-enolase.	0.844
Eno2	I79_007738	G3GUQ0	G3HBB3	Gamma-enolase.	Pyruvate kinase isozymes M1/M2.	0.519
Eno2	I79_016125	G3GUQ0	G3HYJ2	Gamma-enolase.	Pyruvate kinase isozymes M1/M2.	0.519
Eno2	I79_020424	G3GUQ0	G3IA08	Gamma-enolase.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.519
Eno2	I79_020755	G3GUQ0	G3IAX3	Gamma-enolase.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.519