(44 nodes) Lipid storage network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_023498	Seipin. (163 aa)
	I79_023496	Seipin. (71 aa)
	Tmem159	Promethin. (164 aa)
	Enpp1	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
	Apoa1	Apolipoprotein A-I. (264 aa)
	I79_018750	Phosphatidate cytidylyltransferase; Belongs to the CDS family. (367 aa)
	Pnpla2	Patatin-like phospholipase domain-containing protein 2. (486 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
	Fitm2	Fat storage-inducing transmembrane protein 2. (262 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	I79_015800	Beta-hexosaminidase. (527 aa)
	I79_015798	Beta-hexosaminidase subunit beta. (96 aa)
	Dgat1	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family. (327 aa)
	I79_015201	Beta-1,4 N-acetylgalactosaminyltransferase 1. (404 aa)
	I79_015159	O-acyltransferase. (578 aa)
	Dgat2	Diacylglycerol O-acyltransferase 2. (388 aa)
	CgPICR_017510	SMIM22. (90 aa)
	I79_013066	Dysferlin. (1296 aa)
	Apoe	Apolipoprotein E. (313 aa)
	Cry1	Cryptochrome-1. (428 aa)
	Zfyve1	Zinc finger FYVE domain-containing protein 1. (513 aa)
	I79_012286	Zinc finger FYVE domain-containing protein 1. (211 aa)
	Plin2	Perilipin; Belongs to the perilipin family. (432 aa)
	I79_025216	Beta-hexosaminidase subunit beta. (74 aa)
	Sqle	Squalene monooxygenase. (187 aa)
	I79_025852	Squalene monooxygenase. (91 aa)
	I79_025961	Squalene monooxygenase. (100 aa)
	I79_011940	Platelet glycoprotein 4; Belongs to the CD36 family. (348 aa)
	I79_011712	Signal transducer and activator of transcription. (793 aa)
	I79_011711	Signal transducer and activator of transcription 5B. (274 aa)
	I79_010194	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (387 aa)
	I79_008571	UPF0554 protein C2orf43-like. (354 aa)
	Fitm1	Fat storage-inducing transmembrane protein 1. (287 aa)
	Plin3	Perilipin; Belongs to the perilipin family. (440 aa)
	I79_008173	Perilipin; Belongs to the perilipin family. (419 aa)
	Gba	Glucosylceramidase. (515 aa)
	Cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
	Gm2a	Ganglioside GM2 activator. (191 aa)
	Nrip1	Nuclear receptor-interacting protein 1. (1172 aa)
	Cds2	Phosphatidate cytidylyltransferase; Belongs to the CDS family. (208 aa)
	Hexa	Beta-hexosaminidase. (528 aa)
	Cry2	Cryptochrome-2. (577 aa)
	Rnf213	Protein ALO17. (755 aa)
	Bscl2	Leucine-rich repeat neuronal protein 4. (224 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Apoa1	Apoe	G3I7Q1	G3HPC9	Apolipoprotein A-I.	Apolipoprotein E.	0.849
Apoa1	I79_011940	G3I7Q1	G3HMH7	Apolipoprotein A-I.	Platelet glycoprotein 4; Belongs to the CD36 family.	0.406
Apoe	Apoa1	G3HPC9	G3I7Q1	Apolipoprotein E.	Apolipoprotein A-I.	0.849
Apoe	I79_011940	G3HPC9	G3HMH7	Apolipoprotein E.	Platelet glycoprotein 4; Belongs to the CD36 family.	0.516
Apoe	IL1B	G3HPC9	G3I1B0	Apolipoprotein E.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.481
Apoe	Tnf	G3HPC9	G3HZG9	Apolipoprotein E.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.500
Cav1	I79_011940	G3H9I8	G3HMH7	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Platelet glycoprotein 4; Belongs to the CD36 family.	0.415
Cav1	Plin2	G3H9I8	G3IKA3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Perilipin; Belongs to the perilipin family.	0.462
Cav1	Plin3	G3H9I8	G3HCI0	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Perilipin; Belongs to the perilipin family.	0.453
Cry1	Cry2	G3HNX1	G3GYH7	Cryptochrome-1.	Cryptochrome-2.	0.993
Cry2	Cry1	G3GYH7	G3HNX1	Cryptochrome-2.	Cryptochrome-1.	0.993
Dgat1	Dgat2	G3HWM3	G3HUS2	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	Diacylglycerol O-acyltransferase 2.	0.995
Dgat1	I79_011940	G3HWM3	G3HMH7	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	Platelet glycoprotein 4; Belongs to the CD36 family.	0.486
Dgat1	Plin2	G3HWM3	G3IKA3	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	Perilipin; Belongs to the perilipin family.	0.474
Dgat1	Pnpla2	G3HWM3	G3I3H3	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	Patatin-like phospholipase domain-containing protein 2.	0.965
Dgat2	Dgat1	G3HUS2	G3HWM3	Diacylglycerol O-acyltransferase 2.	Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.	0.995
Dgat2	I79_015159	G3HUS2	G3HW11	Diacylglycerol O-acyltransferase 2.	O-acyltransferase.	0.542
Dgat2	I79_025852	G3HUS2	G3IPE5	Diacylglycerol O-acyltransferase 2.	Squalene monooxygenase.	0.408
Dgat2	I79_025961	G3HUS2	G3IPP2	Diacylglycerol O-acyltransferase 2.	Squalene monooxygenase.	0.408
Dgat2	Plin2	G3HUS2	G3IKA3	Diacylglycerol O-acyltransferase 2.	Perilipin; Belongs to the perilipin family.	0.421