STRINGSTRING
I79_023844 I79_023844 Mfng Mfng Dock10 Dock10 I79_024868 I79_024868 Kit Kit Hhex Hhex I79_025546 I79_025546 I79_001990 I79_001990 I79_002104 I79_002104 Irf2bp2 Irf2bp2 Ezh2 Ezh2 Ifnb1 Ifnb1 I79_002594 I79_002594 I79_002595 I79_002595 I79_002596 I79_002596 I79_002597 I79_002597 Gps2 Gps2 Ptprj Ptprj Rag2 Rag2 I79_012691 I79_012691 Notch2 Notch2 Dll1 Dll1 I79_012384 I79_012384 I79_012336 I79_012336 Traf3ip2 Traf3ip2 Polm Polm I79_011711 I79_011711 Ada Ada I79_010700 I79_010700 Ifnk Ifnk Syk Syk Gpr183 Gpr183 Ikzf1 Ikzf1 I79_009632 I79_009632 I79_009585 I79_009585 I79_009416 I79_009416 Tcf3 Tcf3 I79_008982 I79_008982 I79_008354 I79_008354 I79_008311 I79_008311 Nfatc1 Nfatc1 I79_007981 I79_007981 I79_007700 I79_007700 Atp11c Atp11c DNAJB9 DNAJB9 Pou2af1 Pou2af1 I79_005129 I79_005129 Jak3 Jak3 Bcl11a Bcl11a Pik3r1 Pik3r1 Zbtb1 Zbtb1 Fnip1 Fnip1 Msh2 Msh2 Ikzf3 Ikzf3 I79_005968 I79_005968 Slc25a43 Slc25a43 Dock11 Dock11 Dcaf1 Dcaf1 Fzd9 Fzd9 TSHR TSHR Ep300 Ep300 Lgals1 Lgals1 Clcf1 Clcf1 Tcirg1 Tcirg1 Adgrg3 Adgrg3 I79_017613 I79_017613 I79_016921 I79_016921 I79_016914 I79_016914 Ifne Ifne I79_016869 I79_016869 I79_016868 I79_016868 I79_016867 I79_016867 CgPICR_010786 CgPICR_010786 I79_016863 I79_016863 I79_016862 I79_016862 I79_016859 I79_016859 Nfam1 Nfam1 I79_016810 I79_016810 I79_016618 I79_016618 Cdh17 Cdh17 Lgals8 Lgals8 Itm2a Itm2a I79_015223 I79_015223 I79_015109 I79_015109 Tpd52 Tpd52 Il21 Il21 I79_013189 I79_013189 Spib Spib I79_020066 I79_020066 I79_020464 I79_020464 Enpp1 Enpp1 Rbpj Rbpj Lfng Lfng I79_001680 I79_001680 Itfg2 Itfg2 Sp3 Sp3 I79_001029 I79_001029 Bcl6 Bcl6 Foxp1 Foxp1 Irf8 Irf8 Plcg2 Plcg2 I79_000137 I79_000137 Bak1 Bak1 I79_021676 I79_021676 I79_021679 I79_021679 Hdac7 Hdac7 Lrrc8a Lrrc8a I79_023268 I79_023268 I79_023305 I79_023305
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_023844E3 ubiquitin-protein ligase synoviolin. (661 aa)
MfngBeta-1,3-N-acetylglucosaminyltransferase manic fringe. (324 aa)
Dock10Dedicator of cytokinesis protein 10; Belongs to the DOCK family. (189 aa)
I79_024868Membrane-spanning 4-domains subfamily A member 12. (263 aa)
KitMast/stem cell growth factor receptor. (452 aa)
HhexHematopoietically-expressed homeobox protein Hhex. (98 aa)
I79_025546CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransferase; Belongs to the glycosyltransferase 29 family. (340 aa)
I79_001990Myb proto-oncogene protein. (650 aa)
I79_002104FL cytokine receptor. (890 aa)
Irf2bp2Interferon regulatory factor 2-binding protein 2. (347 aa)
Ezh2Histone-lysine N-methyltransferase EZH2. (746 aa)
Ifnb1Interferon beta. (182 aa)
I79_002594Interferon alpha-12. (186 aa)
I79_002595Interferon alpha-12. (190 aa)
I79_002596Interferon alpha-9. (212 aa)
I79_002597Interferon alpha-12. (186 aa)
Gps2G protein pathway suppressor 2. (327 aa)
PtprjReceptor-type tyrosine-protein phosphatase eta. (1077 aa)
Rag2V(D)J recombination-activating protein 2. (527 aa)
I79_012691CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransferase; Belongs to the glycosyltransferase 29 family. (208 aa)
Notch2Neurogenic locus notch-like protein 2. (1521 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
I79_012384Leukocyte common antigen. (962 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
Traf3ip2Adapter protein CIKS. (560 aa)
PolmDNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (491 aa)
I79_011711Signal transducer and activator of transcription 5B. (274 aa)
AdaAdenosine deaminase. (363 aa)
I79_010700Transcription factor Sp3. (441 aa)
IfnkInterferon kappa. (244 aa)
SykTyrosine-protein kinase. (611 aa)
Gpr183G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (357 aa)
Ikzf1DNA-binding protein Ikaros. (489 aa)
I79_009632GON-4-like protein. (1267 aa)
I79_009585Tyrosine-protein kinase receptor. (727 aa)
I79_009416Serine-protein kinase ATM. (1640 aa)
Tcf3Transcription factor E2-alpha. (643 aa)
I79_008982ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (269 aa)
I79_008354Protein lyl-1. (174 aa)
I79_008311B-cell antigen receptor complex-associated protein beta chain. (211 aa)
Nfatc1Nuclear factor of activated T-cells, cytoplasmic 1. (203 aa)
I79_007981GON-4-like protein. (745 aa)
I79_007700GTPase IMAP family member 1. (160 aa)
Atp11cPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (758 aa)
DNAJB9DnaJ homolog subfamily B member 9; Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins. In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1. Also involved in endoplasmic reticulum-ass [...] (222 aa)
Pou2af1POU domain class 2-associating factor 1. (299 aa)
I79_005129Tyrosine-protein kinase JAK3. (330 aa)
Jak3Tyrosine-protein kinase JAK3. (222 aa)
Bcl11aB-cell lymphoma/leukemia 11A. (749 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
Zbtb1Zinc finger and BTB domain-containing protein 1. (713 aa)
Fnip1Folliculin-interacting protein 1. (1435 aa)
Msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (852 aa)
Ikzf3Zinc finger protein Aiolos. (457 aa)
I79_005968CD40 ligand; Belongs to the tumor necrosis factor family. (219 aa)
Slc25a43ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (419 aa)
Dock11Dedicator of cytokinesis protein 11; Belongs to the DOCK family. (601 aa)
Dcaf1Protein VPRBP. (1529 aa)
Fzd9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (439 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (533 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
Lgals1Galectin. (135 aa)
Clcf1Cardiotrophin-like cytokine factor 1. (225 aa)
Tcirg1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (835 aa)
Adgrg3Putative G-protein coupled receptor 97; Belongs to the G-protein coupled receptor 2 family. (550 aa)
I79_017613DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3486 aa)
I79_016921B-cell antigen receptor complex-associated protein alpha chain. (181 aa)
I79_016914POU domain, class 2, transcription factor 2. (116 aa)
IfneInterferon epsilon. (192 aa)
I79_016869Interferon alpha-12. (190 aa)
I79_016868Interferon alpha-12. (180 aa)
I79_016867Interferon alpha-6. (193 aa)
CgPICR_010786Interferon alpha-12. (189 aa)
I79_016863Interferon alpha-12. (190 aa)
I79_016862Interferon alpha-12. (190 aa)
I79_016859Interferon alpha-12. (183 aa)
Nfam1NFAT activation molecule 1. (175 aa)
I79_016810Serine-protein kinase ATM. (473 aa)
I79_016618Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (470 aa)
Cdh17Cadherin-17. (782 aa)
Lgals8Galectin. (316 aa)
Itm2aIntegral membrane protein 2A-like isoform 1. (367 aa)
I79_015223Neurogenic locus notch-like protein 2. (248 aa)
I79_015109Interleukin-6. (174 aa)
Tpd52Tumor protein D52. (245 aa)
Il21Interleukin-21. (67 aa)
I79_013189RT1 class II histocompatibility antigen, B-1 beta chain. (165 aa)
SpibTranscription factor Spi-B. (269 aa)
I79_020066CCAAT/enhancer-binding protein gamma. (93 aa)
I79_020464Interleukin-9 receptor. (320 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
RbpjRecombining binding protein suppressor of hairless-like protein. (486 aa)
LfngBeta-1,3-N-acetylglucosaminyltransferase. (378 aa)
I79_001680Caspase recruitment domain-containing protein 11. (1089 aa)
Itfg2Integrin-alpha FG-GAP repeat-containing protein 2. (443 aa)
Sp3Transcription factor Sp3. (338 aa)
I79_001029Tumor necrosis factor ligand superfamily member 13B; Belongs to the tumor necrosis factor family. (277 aa)
Bcl6B-cell lymphoma 6 protein-like. (707 aa)
Foxp1Forkhead box protein P1. (696 aa)
Irf8Interferon regulatory factor 8. (424 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1199 aa)
I79_000137One cut domain family member. (431 aa)
Bak1Bcl-2-likeous antagonist/killer. (209 aa)
I79_021676Complement receptor type 2. (1038 aa)
I79_021679POU domain protein. (218 aa)
Hdac7Histone deacetylase 7. (424 aa)
Lrrc8aLeucine-rich repeat-containing protein 8A. (810 aa)
I79_023268Disintegrin and metalloproteinase domain-containing protein 17. (527 aa)
I79_023305Dedicator of cytokinesis protein 10; Belongs to the DOCK family. (1362 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (16%) [HD]