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Sp3 Sp3 I79_023145 I79_023145 Pde1b Pde1b Gpr68 Gpr68 PPARG PPARG Thoc5 Thoc5 I79_010700 I79_010700 I79_010234 I79_010234 Pir Pir I79_009953 I79_009953 Mef2c Mef2c I79_006254 I79_006254 Med1 Med1 Csf2 Csf2 Fasn Fasn
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sp3Transcription factor Sp3. (338 aa)
I79_023145Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1948 aa)
Pde1bPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (117 aa)
Gpr68Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Thoc5THO complex subunit 5-like. (683 aa)
I79_010700Transcription factor Sp3. (441 aa)
I79_010234Interleukin-31 receptor A. (530 aa)
PirPirin; Belongs to the pirin family. (178 aa)
I79_009953Transcription factor AP-1. (72 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (95 aa)
FasnFatty acid synthase. (2503 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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