(18 nodes) Lipoprotein particle receptor activity network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Scarb1	Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
	LDLR	Low-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family. (862 aa)
	I79_025297	Very low-density lipoprotein receptor. (558 aa)
	I79_024722	Low-density lipoprotein receptor-related protein 1B. (148 aa)
	Apobr	Apolipoprotein B-100 receptor. (968 aa)
	I79_022918	Low-density lipoprotein receptor-related protein 1B. (274 aa)
	I79_021718	Low-density lipoprotein receptor-related protein 10. (264 aa)
	I79_020923	Low-density lipoprotein receptor-related protein 1B. (254 aa)
	I79_020064	Low-density lipoprotein receptor-related protein 3. (767 aa)
	I79_015046	Low-density lipoprotein receptor. (160 aa)
	I79_014945	Low-density lipoprotein receptor-related protein 12. (85 aa)
	Atp5f1b	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (534 aa)
	Lrp10	Low-density lipoprotein receptor-related protein 10. (716 aa)
	I79_013136	Stabilin-2. (1803 aa)
	I79_011940	Platelet glycoprotein 4; Belongs to the CD36 family. (348 aa)
	Lrp6	Low-density lipoprotein receptor-related protein 6. (565 aa)
	I79_007641	Low-density lipoprotein receptor-related protein 6. (543 aa)
	I79_001015	Low-density lipoprotein receptor-related protein 8. (764 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I79_001015	I79_025297	G3GTN0	G3IMZ0	Low-density lipoprotein receptor-related protein 8.	Very low-density lipoprotein receptor.	0.610
I79_007641	I79_022918	G3HB26	G3IGK1	Low-density lipoprotein receptor-related protein 6.	Low-density lipoprotein receptor-related protein 1B.	0.418
I79_011940	I79_025297	G3HMH7	G3IMZ0	Platelet glycoprotein 4; Belongs to the CD36 family.	Very low-density lipoprotein receptor.	0.425
I79_020923	I79_022918	G3IBA3	G3IGK1	Low-density lipoprotein receptor-related protein 1B.	Low-density lipoprotein receptor-related protein 1B.	0.533
I79_020923	I79_024722	G3IBA3	G3ILF7	Low-density lipoprotein receptor-related protein 1B.	Low-density lipoprotein receptor-related protein 1B.	0.630
I79_022918	I79_007641	G3IGK1	G3HB26	Low-density lipoprotein receptor-related protein 1B.	Low-density lipoprotein receptor-related protein 6.	0.418
I79_022918	I79_020923	G3IGK1	G3IBA3	Low-density lipoprotein receptor-related protein 1B.	Low-density lipoprotein receptor-related protein 1B.	0.533
I79_022918	I79_024722	G3IGK1	G3ILF7	Low-density lipoprotein receptor-related protein 1B.	Low-density lipoprotein receptor-related protein 1B.	0.924
I79_024722	I79_020923	G3ILF7	G3IBA3	Low-density lipoprotein receptor-related protein 1B.	Low-density lipoprotein receptor-related protein 1B.	0.630
I79_024722	I79_022918	G3ILF7	G3IGK1	Low-density lipoprotein receptor-related protein 1B.	Low-density lipoprotein receptor-related protein 1B.	0.924
I79_025297	I79_001015	G3IMZ0	G3GTN0	Very low-density lipoprotein receptor.	Low-density lipoprotein receptor-related protein 8.	0.610
I79_025297	I79_011940	G3IMZ0	G3HMH7	Very low-density lipoprotein receptor.	Platelet glycoprotein 4; Belongs to the CD36 family.	0.425
I79_025297	LDLR	G3IMZ0	P35950	Very low-density lipoprotein receptor.	Low-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family.	0.586
I79_025297	Scarb1	G3IMZ0	G3HX53	Very low-density lipoprotein receptor.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.435
LDLR	I79_025297	P35950	G3IMZ0	Low-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family.	Very low-density lipoprotein receptor.	0.586
LDLR	Scarb1	P35950	G3HX53	Low-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.465
Scarb1	I79_025297	G3HX53	G3IMZ0	Scavenger receptor class B member 1; Belongs to the CD36 family.	Very low-density lipoprotein receptor.	0.435
Scarb1	LDLR	G3HX53	P35950	Scavenger receptor class B member 1; Belongs to the CD36 family.	Low-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family.	0.465