(14 nodes) Male sex determination network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_009795	Mitogen-activated protein kinase kinase kinase 4. (1824 aa)
	Sf1	Splicing factor 1. (522 aa)
	Nr0b1	Nuclear receptor subfamily 0 group B member 1. (470 aa)
	Insr	Insulin receptor. (114 aa)
	I79_009586	Tyrosine-protein kinase receptor. (1183 aa)
	Igf1r	Insulin-like growth factor 1 receptor. (191 aa)
	I79_000973	Transcription factor SOX-10. (360 aa)
	Nr5a1	Steroidogenic factor 1. (462 aa)
	I79_020666	Prostaglandin D2 receptor. (337 aa)
	I79_022007	Homeobox protein SIX4. (673 aa)
	Ar	Androgen receptor. (517 aa)
	Dmrt1	Doublesex-and mab-3-related transcription factor 1. (158 aa)
	I79_006679	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
	I79_019286	Androgen receptor. (295 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ar	Dmrt1	G3IGU9	G3IJW3	Androgen receptor.	Doublesex-and mab-3-related transcription factor 1.	0.411
Ar	I79_019286	G3IGU9	G3I705	Androgen receptor.	Androgen receptor.	0.915
Ar	Igf1r	G3IGU9	G3HKI5	Androgen receptor.	Insulin-like growth factor 1 receptor.	0.527
Dmrt1	Ar	G3IJW3	G3IGU9	Doublesex-and mab-3-related transcription factor 1.	Androgen receptor.	0.411
Dmrt1	I79_000973	G3IJW3	G3GTI9	Doublesex-and mab-3-related transcription factor 1.	Transcription factor SOX-10.	0.571
Dmrt1	I79_019286	G3IJW3	G3I705	Doublesex-and mab-3-related transcription factor 1.	Androgen receptor.	0.401
Dmrt1	Nr0b1	G3IJW3	G3HXG4	Doublesex-and mab-3-related transcription factor 1.	Nuclear receptor subfamily 0 group B member 1.	0.703
I79_000973	Dmrt1	G3GTI9	G3IJW3	Transcription factor SOX-10.	Doublesex-and mab-3-related transcription factor 1.	0.571
I79_000973	I79_006679	G3GTI9	G3H8H9	Transcription factor SOX-10.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.511
I79_000973	Nr5a1	G3GTI9	G3I9D5	Transcription factor SOX-10.	Steroidogenic factor 1.	0.702
I79_006679	I79_000973	G3H8H9	G3GTI9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transcription factor SOX-10.	0.511
I79_009586	Igf1r	G3HG67	G3HKI5	Tyrosine-protein kinase receptor.	Insulin-like growth factor 1 receptor.	0.649
I79_009586	Insr	G3HG67	G3HWV6	Tyrosine-protein kinase receptor.	Insulin receptor.	0.857
I79_019286	Ar	G3I705	G3IGU9	Androgen receptor.	Androgen receptor.	0.915
I79_019286	Dmrt1	G3I705	G3IJW3	Androgen receptor.	Doublesex-and mab-3-related transcription factor 1.	0.401
I79_019286	Igf1r	G3I705	G3HKI5	Androgen receptor.	Insulin-like growth factor 1 receptor.	0.432
I79_019286	Insr	G3I705	G3HWV6	Androgen receptor.	Insulin receptor.	0.405
Igf1r	Ar	G3HKI5	G3IGU9	Insulin-like growth factor 1 receptor.	Androgen receptor.	0.527
Igf1r	I79_009586	G3HKI5	G3HG67	Insulin-like growth factor 1 receptor.	Tyrosine-protein kinase receptor.	0.649
Igf1r	I79_019286	G3HKI5	G3I705	Insulin-like growth factor 1 receptor.	Androgen receptor.	0.432