STRINGSTRING
Phospho1 Phospho1 Asgr2 Asgr2 Lep Lep I79_003741 I79_003741 I79_004409 I79_004409 I79_005088 I79_005088 Igf1 Igf1 Axin2 Axin2 Ptn Ptn Ankh Ankh Cer1 Cer1 Zmpste24 Zmpste24 Sbno2 Sbno2 I79_009217 I79_009217 I79_009708 I79_009708 Alpl Alpl I79_010839 I79_010839 Fgfr3 Fgfr3 I79_011304 I79_011304 I79_011333 I79_011333 Gata1 Gata1 Clec3b Clec3b Ercc2 Ercc2 I79_012652 I79_012652 Wnt11 Wnt11 Gpnmb Gpnmb I79_015207 I79_015207 I79_015880 I79_015880 Hif1a Hif1a I79_016597 I79_016597 Pth Pth I79_018047 I79_018047 Klf10 Klf10 Dlk1 Dlk1 Lgr4 Lgr4 Fgr Fgr Pthlh Pthlh Enpp1 Enpp1 Ift80 Ift80 I79_020783 I79_020783 Icmt Icmt Ifitm5 Ifitm5 Sbds Sbds Atf4 Atf4 Tcf7l2 Tcf7l2 Ano6 Ano6 I79_024083 I79_024083 Fgfr2 Fgfr2 Spp1 Spp1 Ibsp Ibsp Mtss1 Mtss1 I79_025277 I79_025277 I79_025387 I79_025387 I79_025400 I79_025400 Smpd3 Smpd3 I79_025697 I79_025697 I79_025974 I79_025974 I79_000973 I79_000973 H671_2g5863 H671_2g5863 Phospho2 Phospho2 I79_001476 I79_001476 Pkdcc Pkdcc Slc24a3 Slc24a3 Ptgs2 Ptgs2 Col1a2 Col1a2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Phospho1Phosphoethanolamine/phosphocholine phosphatase. (248 aa)
Asgr2Asialoglycoprotein receptor 2. (303 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
I79_003741Dual oxidase 2. (1367 aa)
I79_004409Sorting nexin-10. (214 aa)
I79_005088Cartilage oligomeric matrix protein. (585 aa)
Igf1Insulin-like growth factor I. (75 aa)
Axin2Axin-2. (809 aa)
PtnPleiotrophin. (168 aa)
AnkhProgressive ankylosis protein. (485 aa)
Cer1Cerberus. (272 aa)
Zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
Sbno2Protein strawberry notch-like 2. (669 aa)
I79_009217Protein strawberry notch-like 2. (527 aa)
I79_009708Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (332 aa)
AlplAlkaline phosphatase. (524 aa)
I79_010839Eukaryotic translation initiation factor 2-alpha kinase 3. (783 aa)
Fgfr3Fibroblast growth factor receptor 3. (319 aa)
I79_011304Parathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (626 aa)
I79_011333Sphingomyelin phosphodiesterase 3. (410 aa)
Gata1Erythroid transcription factor-like protein. (330 aa)
Clec3bTetranectin-like protein. (202 aa)
Ercc2TFIIH basal transcription factor complex helicase subunit. (141 aa)
I79_012652TFIIH basal transcription factor complex helicase subunit. (108 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
GpnmbTransmembrane glycoprotein NMB. (610 aa)
I79_01520725-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (232 aa)
I79_015880F-box only protein 37. (399 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
I79_016597Krueppel-like factor 10. (439 aa)
PthParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)
I79_018047Krueppel-like factor 10. (94 aa)
Klf10Krueppel-like factor 10. (212 aa)
Dlk1Protein delta-like 1. (361 aa)
Lgr4Leucine-rich repeat-containing G-protein coupled receptor 4. (231 aa)
FgrTyrosine-protein kinase. (435 aa)
PthlhParathyroid hormone-related protein. (191 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
Ift80Intraflagellar transport protein 80-like. (366 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
IcmtProtein-S-isoprenylcysteine O-methyltransferase. (119 aa)
Ifitm5Interferon-induced transmembrane protein 5. (134 aa)
SbdsRibosome maturation protein SBDS. (181 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (348 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
Ano6Anoctamin. (319 aa)
I79_024083Protein-lysine 6-oxidase. (123 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
Spp1Osteopontin. (117 aa)
IbspBone sialoprotein 2. (315 aa)
Mtss1Metastasis suppressor protein 1. (526 aa)
I79_025277Anoctamin. (281 aa)
I79_025387Krueppel-like factor 10. (314 aa)
I79_025400Anoctamin. (273 aa)
Smpd3Sphingomyelin phosphodiesterase 3. (446 aa)
I79_025697Intraflagellar transport protein 80-like. (113 aa)
I79_025974Metastasis suppressor protein 1. (73 aa)
I79_000973Transcription factor SOX-10. (360 aa)
H671_2g5863Trimeric intracellular cation channel type B-like protein. (176 aa)
Phospho2Pyridoxal phosphate phosphatase PHOSPHO2. (241 aa)
I79_001476Collagenase 3. (300 aa)
PkdccProtein kinase-like protein SgK493. (252 aa)
Slc24a3Sodium/potassium/calcium exchanger 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (561 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
Col1a2Collagen alpha-2(I) chain. (621 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: medium (42%) [HD]