STRINGSTRING
I79_005007 I79_005007 Syt2 Syt2 Akt1 Akt1 Kdm2b Kdm2b Dbn1 Dbn1 Extl3 Extl3 Edn1 Edn1 Zfyve27 Zfyve27 Cxcr4 Cxcr4 Bmpr2 Bmpr2 F2 F2 Derl2 Derl2 Ndel1 Ndel1 I79_002693 I79_002693 Ucn Ucn Itsn2 Itsn2 Uts2r Uts2r I79_002323 I79_002323 I79_025994 I79_025994 Ncoa3 Ncoa3 Avpr1a Avpr1a Mul1 Mul1 Sirt1 Sirt1 Gsk3b Gsk3b I79_007989 I79_007989 Hdgfl2 Hdgfl2 Trip10 Trip10 Adnp2 Adnp2 Sdcbp Sdcbp I79_008485 I79_008485 Cpne6 Cpne6 I79_008724 I79_008724 I79_008941 I79_008941 Sema7a Sema7a I79_009065 I79_009065 Adnp Adnp Dscam Dscam CgPICR_006951 CgPICR_006951 Eif2b2 Eif2b2 Plaa Plaa Sfrp1 Sfrp1 I79_010136 I79_010136 H671_3g8622 H671_3g8622 Cdc42 Cdc42 Map1b Map1b Ngf Ngf Atp5mc1 Atp5mc1 I79_011045 I79_011045 Cpne5 Cpne5 I79_011149 I79_011149 Map3k13 Map3k13 H671_2g6475 H671_2g6475 Igfbp1 Igfbp1 Limk1 Limk1 I79_011638 I79_011638 I79_011641 I79_011641 Rnd2 Rnd2 Dbnl Dbnl I79_012059 I79_012059 I79_012206 I79_012206 Mfsd2a Mfsd2a I79_012336 I79_012336 I79_012556 I79_012556 I79_012610 I79_012610 Apoe Apoe H1-5 H1-5 Myo5b Myo5b Smad7 Smad7 I79_013395 I79_013395 I79_013769 I79_013769 Mecp2 Mecp2 L1cam L1cam I79_014098 I79_014098 I79_014272 I79_014272 I79_014329 I79_014329 Sphk1 Sphk1 Tead1 Tead1 I79_014809 I79_014809 I79_014844 I79_014844 PAFAH1B1 PAFAH1B1 I79_014942 I79_014942 Rims1 Rims1 I79_015181 I79_015181 Lrp1 Lrp1 Usp47 Usp47 Picalm Picalm Smurf1 Smurf1 I79_016148 I79_016148 Slc9a1 Slc9a1 Sfn Sfn Srf Srf DNPH1 DNPH1 Syt1 Syt1 Nrp1 Nrp1 Ddx39b Ddx39b CgPICR_020524 CgPICR_020524 Tnfrsf12a Tnfrsf12a Tmem145 Tmem145 I79_016941 I79_016941 I79_017320 I79_017320 Fn1 Fn1 Eif4g1 Eif4g1 Rufy3 Rufy3 I79_018310 I79_018310 Syt3 Syt3 Nol12 Nol12 I79_018645 I79_018645 Exosc9 Exosc9 Syt4 Syt4 Cxcl12 Cxcl12 I79_019223 I79_019223 Ptk2 Ptk2 I79_019459 I79_019459 Sgk1 Sgk1 Krt17 Krt17 I79_019981 I79_019981 Slc25a4 Slc25a4 I79_020506 I79_020506 Akap6 Akap6 Lpar3 Lpar3 Gdi1 Gdi1 Psmd10 Psmd10 Ocm2 Ocm2 I79_021404 I79_021404 H671_xg20331 H671_xg20331 I79_021577 I79_021577 I79_021789 I79_021789 Cfl1 Cfl1 Efna5 Efna5 Exosc2 Exosc2 Mtor Mtor Anapc2 Anapc2 I79_023268 I79_023268 Cib1 Cib1 Ntrk3 Ntrk3 Syt17 Syt17 I79_023605 I79_023605 Cntf Cntf I79_023875 I79_023875 I79_024271 I79_024271 Fxn Fxn Fam122a Fam122a I79_024393 I79_024393 I79_024406 I79_024406 I79_024437 I79_024437 Pak1 Pak1 Commd5 Commd5 I79_025549 I79_025549 I79_025570 I79_025570 I79_025672 I79_025672 I79_025812 I79_025812 I79_025858 I79_025858 I79_026256 I79_026256 Rptor Rptor I79_002288 I79_002288 I79_002264 I79_002264 Cdh4 Cdh4 Trpv2 Trpv2 Brat1 Brat1 I79_001634 I79_001634 I79_001484 I79_001484 I79_001303 I79_001303 I79_000772 I79_000772 Cdkn2aip Cdkn2aip I79_000682 I79_000682 I79_000233 I79_000233 Adam10 Adam10 I79_000092 I79_000092 ilk ilk I79_006792 I79_006792 Skor1 Skor1 I79_006739 I79_006739 I79_006416 I79_006416 I79_006386 I79_006386 Sema5a Sema5a Tgfbr1 Tgfbr1 I79_006282 I79_006282 Supv3l1 Supv3l1 I79_005909 I79_005909 Igf1 Igf1 Erbb2 Erbb2 I79_005573 I79_005573 Unc13a Unc13a Ddx49 Ddx49
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_005007Solute carrier family 23 member 2. (933 aa)
Syt2Synaptotagmin-2. (419 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Kdm2bLysine-specific demethylase 2B. (1305 aa)
Dbn1Drebrin. (597 aa)
Extl3Exostosin-like 3; Belongs to the glycosyltransferase 47 family. (919 aa)
Edn1Endothelin-1. (202 aa)
Zfyve27Zinc finger FYVE domain-containing protein 27. (404 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (290 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
Derl2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (113 aa)
Ndel1Nuclear distribution protein nudE-like 1. (345 aa)
I79_002693Netrin-1. (252 aa)
UcnUrocortin. (122 aa)
Itsn2Intersectin-2. (1652 aa)
Uts2rUrotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (387 aa)
I79_002323Copine-9. (581 aa)
I79_025994WNT1-inducible-signaling pathway protein 1. (136 aa)
Ncoa3Nuclear receptor coactivator 3. (1211 aa)
Avpr1aVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa)
Mul1Mitochondrial ubiquitin ligase activator of NFKB 1. (321 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
Gsk3bGlycogen synthase kinase-3 beta. (328 aa)
I79_007989Farnesyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. (375 aa)
Hdgfl2Hepatoma-derived growth factor-related protein 2. (668 aa)
Trip10Cdc42-interacting protein 4. (610 aa)
Adnp2ADNP homeobox protein 2. (1165 aa)
SdcbpSyntenin-1. (298 aa)
I79_008485Cofilin-1; Belongs to the actin-binding proteins ADF family. (111 aa)
Cpne6Copine-6. (563 aa)
I79_00872460S ribosomal protein L4. (198 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
Sema7aSemaphorin-7A; Belongs to the semaphorin family. (560 aa)
I79_009065Kelch-like protein 22. (399 aa)
AdnpActivity-dependent neuroprotector homeobox protein. (1102 aa)
DscamDown syndrome cell adhesion molecule. (1231 aa)
CgPICR_00695160S ribosomal protein L4. (204 aa)
Eif2b2Translation initiation factor eIF-2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (257 aa)
PlaaPhospholipase A-2-activating protein. (795 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_010136Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (230 aa)
H671_3g8622Semaphorin-4D; Belongs to the semaphorin family. (833 aa)
Cdc42Cell division control protein 42-like. (191 aa)
Map1bMicrotubule-associated protein 1B. (2371 aa)
NgfBeta-nerve growth factor; Belongs to the NGF-beta family. (112 aa)
Atp5mc1ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (136 aa)
I79_011045Afadin. (1605 aa)
Cpne5Copine-5. (314 aa)
I79_011149Copine-5. (243 aa)
Map3k13Mitogen-activated protein kinase kinase kinase 13. (431 aa)
H671_2g6475ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. (136 aa)
Igfbp1Insulin-like growth factor-binding protein 1. (272 aa)
Limk1LIM domain kinase 1. (283 aa)
I79_01163860S ribosomal protein L4. (143 aa)
I79_011641Lithostathine-2. (214 aa)
Rnd2Next to BRCA1 gene 1 protein. (864 aa)
DbnlDrebrin-like protein. (433 aa)
I79_012059Tripartite motif-containing protein 32. (556 aa)
I79_012206Microtubule-actin cross-linking factor 1, isoform 4. (7148 aa)
Mfsd2aMajor facilitator superfamily domain-containing protein 2. (527 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
I79_012556Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1227 aa)
I79_012610Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (865 aa)
ApoeApolipoprotein E. (313 aa)
H1-5Histone H1.5. (222 aa)
Myo5bMyosin-Vb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2009 aa)
Smad7Mothers against decapentaplegic-like 7. (256 aa)
I79_013395Matrix metalloproteinase-14. (539 aa)
I79_013769E3 ubiquitin-protein ligase NEDD4-like. (182 aa)
Mecp2Methyl-CpG-binding protein 2. (203 aa)
L1camNeural cell adhesion molecule L1. (1287 aa)
I79_014098Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
I79_01427260S ribosomal protein L4. (175 aa)
I79_014329Histone H3.3. (102 aa)
Sphk1Sphingosine kinase 1. (383 aa)
Tead1Transcriptional enhancer factor TEF-1. (432 aa)
I79_014809Histone H3.3 type 1. (89 aa)
I79_014844Histone H3.3. (140 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
I79_014942Regulating synaptic membrane exocytosis protein 2. (694 aa)
Rims1Regulating synaptic membrane exocytosis protein 1. (215 aa)
I79_01518114-3-3 protein sigma; Belongs to the 14-3-3 family. (249 aa)
Lrp1Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
Usp47Ubiquitin carboxyl-terminal hydrolase 47. (754 aa)
PicalmPhosphatidylinositol-binding clathrin assembly protein. (604 aa)
Smurf1E3 ubiquitin-protein ligase SMURF1. (303 aa)
I79_016148Eukaryotic translation initiation factor 4 gamma 2. (783 aa)
Slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (821 aa)
Sfn14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
SrfSerum response factor. (361 aa)
DNPH12'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. (163 aa)
Syt1Synaptotagmin-1. (422 aa)
Nrp1Neuropilin; Belongs to the neuropilin family. (923 aa)
Ddx39bSpliceosome RNA helicase BAT1. (288 aa)
CgPICR_020524ARMC12. (344 aa)
Tnfrsf12aTumor necrosis factor receptor superfamily member 12A. (124 aa)
Tmem145Multiple epidermal growth factor-like domains 8. (2639 aa)
I79_016941Histone H3.3. (114 aa)
I79_017320Poly [ADP-ribose] polymerase. (513 aa)
Fn1Fibronectin. (2486 aa)
Eif4g1Eukaryotic translation initiation factor 4 gamma 1. (1590 aa)
Rufy3Protein RUFY3. (542 aa)
I79_018310FGFR1 oncogene partner. (281 aa)
Syt3Synaptotagmin-3. (570 aa)
Nol12Nucleolar protein 12. (215 aa)
I79_018645Exosome complex exonuclease RRP45. (76 aa)
Exosc9Exosome complex exonuclease RRP45. (386 aa)
Syt4Synaptotagmin-4. (243 aa)
Cxcl12Stromal cell-derived factor 1. (89 aa)
I79_019223RasGAP-activating-like protein 1. (761 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1027 aa)
I79_019459Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (232 aa)
Sgk1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
Krt17Keratin, type I cytoskeletal 17; Belongs to the intermediate filament family. (432 aa)
I79_019981Lysine-specific demethylase 2B. (484 aa)
Slc25a4ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (272 aa)
I79_020506POU domain, class 4, transcription factor 2. (207 aa)
Akap6A-kinase anchor protein 6. (1368 aa)
Lpar3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (352 aa)
Gdi1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (425 aa)
Psmd1026S proteasome non-ATPase regulatory subunit 10. (218 aa)
Ocm2Oncomodulin; Belongs to the parvalbumin family. (128 aa)
I79_021404Putative DNA helicase INO80 complex-like 1. (1058 aa)
H671_xg20331Eukaryotic translation initiation factor 4 gamma 1 isoform 1. (309 aa)
I79_021577Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (248 aa)
I79_021789NT-3 growth factor receptor. (389 aa)
Cfl1Cofilin-1; Belongs to the actin-binding proteins ADF family. (166 aa)
Efna5Ephrin-A5; Belongs to the ephrin family. (172 aa)
Exosc2Exosome complex exonuclease RRP4. (291 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
Anapc2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (269 aa)
I79_023268Disintegrin and metalloproteinase domain-containing protein 17. (527 aa)
Cib1Calcium and integrin-binding protein 1. (191 aa)
Ntrk3Tyrosine-protein kinase receptor. (226 aa)
Syt17Synaptotagmin-17. (299 aa)
I79_023605Histone H3.3. (136 aa)
CntfCiliary neurotrophic factor. (59 aa)
I79_023875Tripartite motif-containing protein 32. (265 aa)
I79_024271NT-3 growth factor receptor. (114 aa)
FxnFrataxin, mitochondrial. (136 aa)
Fam122aProtein FAM122A. (286 aa)
I79_024393Cofilin-1. (85 aa)
I79_024406A-kinase anchor protein 6. (211 aa)
I79_024437Enterin neuropeptides. (161 aa)
Pak1Serine/threonine-protein kinase PAK 1. (325 aa)
Commd5COMM domain-containing protein 5. (224 aa)
I79_025549WNT1-inducible-signaling pathway protein 1. (274 aa)
I79_025570Spliceosome RNA helicase Bat1. (229 aa)
I79_025672Spliceosome RNA helicase BAT1. (155 aa)
I79_025812Microtubule-associated protein. (128 aa)
I79_025858Spliceosome RNA helicase BAT1. (66 aa)
I79_026256Spliceosome RNA helicase Bat1. (103 aa)
RptorRegulatory-associated protein of mTOR. (1331 aa)
I79_002288Disrupted in schizophrenia 1-like. (648 aa)
I79_002264Histone H3.3 type 1. (138 aa)
Cdh4Cadherin-4; Cadherins are calcium-dependent cell adhesion proteins. (890 aa)
Trpv2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (756 aa)
Brat1HEAT repeat-containing protein C7orf27. (822 aa)
I79_001634Golgin subfamily A member 4. (1951 aa)
I79_00148465 kDa Yes-associated protein. (257 aa)
I79_001303Regulating synaptic membrane exocytosis protein 1. (167 aa)
I79_000772N(6)-adenine-specific DNA methyltransferase 1. (188 aa)
Cdkn2aipCDKN2A-interacting protein. (330 aa)
I79_000682Histone H3.3. (136 aa)
I79_000233Cytochrome b-245 light chain. (206 aa)
Adam10Disintegrin and metalloproteinase domain-containing protein 10. (675 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
ilkIntegrin-linked protein kinase. (452 aa)
I79_006792DUF1518 domain-containing protein. (200 aa)
Skor1Dual specificity mitogen-activated protein kinase kinase 5. (719 aa)
I79_00673960S ribosomal protein L4. (286 aa)
I79_006416Histone H3.3. (117 aa)
I79_006386Shootin-1. (287 aa)
Sema5aSemaphorin-5A. (1046 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
I79_006282Nuclear cap-binding protein subunit 1. (581 aa)
Supv3l1ATP-dependent RNA helicase SUPV3L1, mitochondrial. (779 aa)
I79_005909Peptidyl-prolyl cis-trans isomerase. (242 aa)
Igf1Insulin-like growth factor I. (75 aa)
Erbb2Receptor protein-tyrosine kinase. (1256 aa)
I79_005573Secreted frizzled-related protein 2. (268 aa)
Unc13aProtein unc-13-like A. (1871 aa)
Ddx49Putative ATP-dependent RNA helicase DDX49; Belongs to the DEAD box helicase family. (480 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (28%) [HD]