STRINGSTRING
I79_022080 I79_022080 I79_017864 I79_017864 Sgms2 Sgms2 I79_017379 I79_017379 Bmp2k Bmp2k Pth Pth Trpm4 Trpm4 I79_016411 I79_016411 Hif1a Hif1a H671_4g12667 H671_4g12667 Acvr2a Acvr2a Rflna Rflna I79_015454 I79_015454 I79_015453 I79_015453 I79_015207 I79_015207 Fam20c Fam20c I79_014629 I79_014629 I79_013535 I79_013535 Acvr2b Acvr2b Ddr2 Ddr2 Omd Omd I79_012336 I79_012336 Suv39h1 Suv39h1 Gata1 Gata1 Kl Kl I79_011453 I79_011453 Adgrv1 Adgrv1 I79_011367 I79_011367 Atp2b1 Atp2b1 Fgfr3 Fgfr3 Wnt4 Wnt4 Tmem119 Tmem119 Acvr1 Acvr1 Bglap Bglap Tgfb3 Tgfb3 I79_009364 I79_009364 Cd276 Cd276 Osr1 Osr1 Bmp6 Bmp6 Zmpste24 Zmpste24 Bmp7 Bmp7 Mef2c Mef2c Ankh Ankh Ptn Ptn Fzd9 Fzd9 Smad3 Smad3 I79_006254 I79_006254 Tent5a Tent5a Mgp Mgp I79_005088 I79_005088 Ecm1 Ecm1 I79_004285 I79_004285 Matn1 Matn1 Bmpr2 Bmpr2 Asxl2 Asxl2 I79_002412 I79_002412 Notum Notum Pkdcc Pkdcc Fgf23 Fgf23 Phospho2 Phospho2 I79_000973 I79_000973 Ostn Ostn Bcor Bcor Gja1 Gja1 I79_025400 I79_025400 I79_025277 I79_025277 Mepe Mepe Ano6 Ano6 I79_023010 I79_023010 S1pr1 S1pr1 Nfe2 Nfe2 Adrb2 Adrb2 Alox5 Alox5 Grem1 Grem1 Enpp1 Enpp1 Tgfb1 Tgfb1 Wnt10b Wnt10b Actn3 Actn3 Isg15 Isg15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_022080Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (402 aa)
I79_017864Fibrillin-2. (2601 aa)
Sgms2Phosphatidylcholine:ceramide cholinephosphotransferase 2. (365 aa)
I79_017379Gamma-taxilin. (401 aa)
Bmp2kBMP-2-inducible protein kinase. (1009 aa)
PthParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)
Trpm4Transient receptor potential cation channel subfamily M member 4. (315 aa)
I79_016411G-protein coupled receptor 98. (86 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
H671_4g12667Alpha-2-HS-glycoprotein. (333 aa)
Acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
RflnaProtein FAM101A. (210 aa)
I79_015454C-C chemokine receptor 1-like protein 1; Belongs to the G-protein coupled receptor 1 family. (329 aa)
I79_015453C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
I79_01520725-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (232 aa)
Fam20cDentin matrix protein 4. (776 aa)
I79_014629Sodium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (369 aa)
I79_013535Fibrillin-3. (1889 aa)
Acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (559 aa)
Ddr2Discoidin domain-containing receptor 2. (854 aa)
OmdOsteomodulin. (419 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
Suv39h1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
Gata1Erythroid transcription factor-like protein. (330 aa)
KlKlotho. (900 aa)
I79_011453G-protein coupled receptor 98. (5280 aa)
Adgrv1G-protein coupled receptor 98. (128 aa)
I79_011367Plasma membrane calcium-transporting ATPase 1. (327 aa)
Atp2b1Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (384 aa)
Fgfr3Fibroblast growth factor receptor 3. (319 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
Tmem119Transmembrane protein 119. (277 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
BglapOsteocalcin; Binds strongly to apatite and calcium. (99 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
I79_009364Transcription factor AP-2 alpha. (411 aa)
Cd276CD276 antigen. (316 aa)
Osr1Protein odd-skipped-related 1. (266 aa)
Bmp6Bone morphogenetic protein 6. (296 aa)
Zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
AnkhProgressive ankylosis protein. (485 aa)
PtnPleiotrophin. (168 aa)
Fzd9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (439 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
Tent5aProtein FAM46A. (428 aa)
MgpMatrix Gla protein; Associates with the organic matrix of bone and cartilage. (94 aa)
I79_005088Cartilage oligomeric matrix protein. (585 aa)
Ecm1Extracellular matrix protein 1. (563 aa)
I79_004285p2X purinoceptor 7. (805 aa)
Matn1Cartilage matrix protein. (461 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
Asxl2Putative Polycomb group protein ASXL2. (1421 aa)
I79_002412Protein notum-like. (444 aa)
NotumProtein notum-like. (354 aa)
PkdccProtein kinase-like protein SgK493. (252 aa)
Fgf23Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
Phospho2Pyridoxal phosphate phosphatase PHOSPHO2. (241 aa)
I79_000973Transcription factor SOX-10. (360 aa)
OstnOsteocrin. (105 aa)
BcorBCL-6 corepressor. (1839 aa)
Gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
I79_025400Anoctamin. (273 aa)
I79_025277Anoctamin. (281 aa)
MepeMatrix extracellular phosphoglycoprotein. (448 aa)
Ano6Anoctamin. (319 aa)
I79_023010Latent-transforming growth factor beta-binding protein 3. (624 aa)
S1pr1Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
Nfe2Transcription factor NF-E2 45 kDa subunit. (374 aa)
Adrb2Beta-2 adrenergic receptor. (337 aa)
Alox5Arachidonate 5-lipoxygenase. (674 aa)
Grem1Gremlin-1. (117 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
Actn3Alpha-actinin-3. (900 aa)
Isg15Ubiquitin-like protein ISG15-like protein. (156 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.