STRINGSTRING
I79_005779 I79_005779 I79_005720 I79_005720 I79_005662 I79_005662 Glra1 Glra1 H671_3g8910 H671_3g8910 Hexa Hexa Clcn3 Clcn3 Crhbp Crhbp Npy Npy I79_004403 I79_004403 Drd2 Drd2 Oprd1 Oprd1 Pum1 Pum1 Hoxd4 Hoxd4 Drd1 Drd1 Chrnb4 Chrnb4 Chrna3 Chrna3 Chrna5 Chrna5 I79_003549 I79_003549 Cln8 Cln8 I79_003212 I79_003212 Gpr39 Gpr39 Lep Lep Slc1a2 Slc1a2 Dmbx1 Dmbx1 I79_002785 I79_002785 I79_002759 I79_002759 Chrnb1 Chrnb1 Mafg Mafg Ghrl Ghrl I79_002195 I79_002195 Kcnma1 Kcnma1 Abat Abat Pmp22 Pmp22 I79_001679 I79_001679 Ccnd2 Ccnd2 Atxn1 Atxn1 Nos1 Nos1 Oprm1 Oprm1 I79_000875 I79_000875 Fgf12 Fgf12 Grik1 Grik1 I79_000658 I79_000658 Trh Trh Dbh Dbh I79_025812 I79_025812 I79_025720 I79_025720 I79_025510 I79_025510 I79_025333 I79_025333 I79_025312 I79_025312 I79_025230 I79_025230 Uchl1 Uchl1 Cstb Cstb Fxn Fxn I79_024066 I79_024066 I79_023173 I79_023173 I79_023172 I79_023172 Arl5a Arl5a I79_022712 I79_022712 I79_025942 I79_025942 I79_022685 I79_022685 Ppara Ppara I79_022390 I79_022390 I79_022316 I79_022316 I79_022199 I79_022199 I79_021745 I79_021745 I79_021577 I79_021577 I79_021185 I79_021185 Atp6v1b1 Atp6v1b1 Lgi4 Lgi4 Slc10a4 Slc10a4 Grin2d Grin2d Inpp5f Inpp5f Agtpbp1 Agtpbp1 Enpp1 Enpp1 I79_020418 I79_020418 Gigyf2 Gigyf2 I79_019616 I79_019616 Htra2 Htra2 Nlgn3 Nlgn3 Cxcl12 Cxcl12 Nrxn2 Nrxn2 Arcn1 Arcn1 I79_018586 I79_018586 I79_018465 I79_018465 I79_018396 I79_018396 Sptbn2 Sptbn2 Sez6l2 Sez6l2 I79_018306 I79_018306 Htr2a Htr2a I79_018131 I79_018131 Tbce Tbce Cend1 Cend1 Drd4 Drd4 I79_017571 I79_017571 I79_017351 I79_017351 Ctns Ctns I79_016917 I79_016917 Klhl1 Klhl1 Htr2c Htr2c Homer1 Homer1 I79_016692 I79_016692 Oprk1 Oprk1 CgPICR_005625 CgPICR_005625 Ehmt2 Ehmt2 Slitrk1 Slitrk1 Foxa2 Foxa2 Gabrg2 Gabrg2 Slitrk5 Slitrk5 I79_015056 I79_015056 I79_014954 I79_014954 PAFAH1B1 PAFAH1B1 Parp1 Parp1 Unc79 Unc79 Sez6l Sez6l I79_014078 I79_014078 Nr4a2 Nr4a2 Mecp2 Mecp2 I79_013707 I79_013707 I79_013706 I79_013706 Slc1a1 Slc1a1 I79_013598 I79_013598 I79_013437 I79_013437 Scn1a Scn1a Fadd Fadd I79_012961 I79_012961 I79_012960 I79_012960 Chd7 Chd7 I79_012815 I79_012815 I79_012814 I79_012814 Shkbp1 Shkbp1 Ppt1 Ppt1 Pcdh15 Pcdh15 Nrxn1 Nrxn1 App App I79_011902 I79_011902 I79_011789 I79_011789 Btbd9 Btbd9 I79_011170 I79_011170 Fgf14 Fgf14 I79_010883 I79_010883 Ngf Ngf I79_010620 I79_010620 Chl1 Chl1 Cartpt Cartpt I79_010469 I79_010469 Hdac2 Hdac2 Chrna4 Chrna4 Ntsr1 Ntsr1 Slitrk6 Slitrk6 I79_009401 I79_009401 Tpgs1 Tpgs1 Septin5 Septin5 I79_009010 I79_009010 Oxr1 Oxr1 Bbs4 Bbs4 I79_008980 I79_008980 I79_008932 I79_008932 Ndufs4 Ndufs4 Zfhx2 Zfhx2 I79_008565 I79_008565 I79_008360 I79_008360 I79_008358 I79_008358 Zmpste24 Zmpste24 Chrnb2 Chrnb2 Cdk5 Cdk5 Gbx1 Gbx1 Cntn2 Cntn2 I79_007529 I79_007529 Asip Asip TSHR TSHR I79_007313 I79_007313 Eps8 Eps8 I79_007152 I79_007152 I79_007063 I79_007063 I79_006961 I79_006961 Pcdh17 Pcdh17 Grm2 Grm2 I79_006562 I79_006562 Kcnj10 Kcnj10 Atp1a2 Atp1a2 Ncstn Ncstn Glrb Glrb I79_006116 I79_006116 Ghsr Ghsr
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_005779Neurexin-3-alpha. (339 aa)
I79_005720Protein phosphatase 1 regulatory subunit 1B. (251 aa)
I79_005662Homeobox protein Hox-B8. (156 aa)
Glra1Glycine receptor subunit alpha-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (413 aa)
H671_3g8910Fibroblast growth factor-binding protein 3. (71 aa)
HexaBeta-hexosaminidase. (528 aa)
Clcn3Chloride channel protein. (866 aa)
CrhbpCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
NpyNeuropeptide Y. (148 aa)
I79_004403D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
Drd2D(2) dopamine receptor. (274 aa)
Oprd1Delta-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (323 aa)
Pum1Pumilio-like 1. (364 aa)
Hoxd4Homeobox protein Hox-D10. (371 aa)
Drd1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (448 aa)
Chrnb4Neuronal acetylcholine receptor subunit beta-4. (496 aa)
Chrna3Neuronal acetylcholine receptor subunit alpha-3. (500 aa)
Chrna5Neuronal acetylcholine receptor subunit alpha-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (234 aa)
I79_003549D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa)
Cln8Protein CLN8. (323 aa)
I79_003212G-protein coupled receptor 39. (151 aa)
Gpr39G-protein coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (289 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Slc1a2Amino acid transporter. (553 aa)
Dmbx1Diencephalon/mesencephalon homeobox protein 1. (378 aa)
I79_002785Beta-arrestin-2. (65 aa)
I79_002759Neuroligin-2. (635 aa)
Chrnb1Acetylcholine receptor subunit beta. (429 aa)
MafgTranscription factor MafG. (162 aa)
GhrlAppetite-regulating hormone. (100 aa)
I79_002195Calcium-activated potassium channel subunit alpha-1. (326 aa)
Kcnma1Uncharacterized protein. (462 aa)
Abat4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
Pmp22Peripheral myelin protein 22. (92 aa)
I79_001679Protein sidekick-1. (1802 aa)
Ccnd2G1/S-specific cyclin-D2; Belongs to the cyclin family. (288 aa)
Atxn1Ataxin-1. (790 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
Oprm1Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (394 aa)
I79_000875Zinc finger protein ZIC 1. (248 aa)
Fgf12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (165 aa)
Grik1Glutamate receptor, ionotropic kainate 1. (778 aa)
I79_000658Kalirin. (2681 aa)
TrhPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (247 aa)
DbhDopamine beta-hydroxylase. (117 aa)
I79_025812Microtubule-associated protein. (128 aa)
I79_025720Corticotropin-releasing factor receptor 1. (134 aa)
I79_025510Kelch-like protein 5. (59 aa)
I79_025333Alcohol dehydrogenase 1. (220 aa)
I79_025312Kelch-like protein 5. (193 aa)
I79_025230Alcohol dehydrogenase 1. (331 aa)
Uchl1Ubiquitin carboxyl-terminal hydrolase. (219 aa)
CstbCystatin-B; Belongs to the cystatin family. (98 aa)
FxnFrataxin, mitochondrial. (136 aa)
I79_024066Doublesex-and mab-3-related transcription factor 3. (415 aa)
I79_023173SH3 and multiple ankyrin repeat domains protein 3. (1107 aa)
I79_023172SH3 and multiple ankyrin repeat domains protein 3. (654 aa)
Arl5aVoltage-dependent L-type calcium channel subunit beta-4. (576 aa)
I79_022712Glutamate [NMDA] receptor subunit zeta-1. (998 aa)
I79_025942Cystinosin. (115 aa)
I79_022685Dopamine beta-hydroxylase. (534 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
I79_022316Kelch-like protein 5. (198 aa)
I79_022199Hamartin. (966 aa)
I79_021745Ubiquitin carboxyl-terminal hydrolase 46. (333 aa)
I79_021577Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (248 aa)
I79_021185Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1931 aa)
Atp6v1b1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (476 aa)
Lgi4Leucine-rich repeat LGI family member 4. (97 aa)
Slc10a4Sodium/bile acid cotransporter 4. (437 aa)
Grin2dGlutamate [NMDA] receptor subunit epsilon-4. (237 aa)
Inpp5fPhosphatidylinositide phosphatase SAC2. (842 aa)
Agtpbp1Cytosolic carboxypeptidase 1. (1087 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
I79_020418Homer protein-like 2. (319 aa)
Gigyf2PERQ amino acid-rich with GYF domain-containing protein 2. (1298 aa)
I79_019616Seizure protein 6. (1017 aa)
Htra2Serine protease HTRA2, mitochondrial. (448 aa)
Nlgn3Neuroligin-3. (828 aa)
Cxcl12Stromal cell-derived factor 1. (89 aa)
Nrxn2Neurexin-2-alpha. (56 aa)
Arcn1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (511 aa)
I79_018586Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
I79_018465SH3 and multiple ankyrin repeat domains protein 1. (1330 aa)
I79_018396Spectrin beta chain, brain 2. (81 aa)
Sptbn2Spectrin beta chain, brain 2. (56 aa)
Sez6l2Seizure 6-like protein 2. (401 aa)
I79_018306Ephrin type-A receptor 4. (932 aa)
Htr2a5-hydroxytryptamine receptor 2A. (264 aa)
I79_0181315-hydroxytryptamine receptor 2A; Belongs to the G-protein coupled receptor 1 family. (237 aa)
TbceTubulin-specific chaperone E. (389 aa)
Cend1Cell cycle exit and neuronal differentiation protein 1. (149 aa)
Drd4D(4) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (387 aa)
I79_017571Pre-B-cell leukemia transcription factor 3. (389 aa)
I79_017351Otogelin. (2309 aa)
CtnsCystinosin. (116 aa)
I79_016917Sodium/potassium-transporting ATPase subunit alpha-3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (632 aa)
Klhl1Kelch-like protein 1. (180 aa)
Htr2c5-hydroxytryptamine receptor 2C. (317 aa)
Homer1Homer protein-like 1. (366 aa)
I79_016692CREB-binding protein. (1054 aa)
Oprk1Kappa-type opioid receptor. (176 aa)
CgPICR_005625Agouti-related protein. (131 aa)
Ehmt2Histone-lysine N-methyltransferase, H3 lysine-9 specific 3. (661 aa)
Slitrk1SLIT and NTRK-like protein 1. (694 aa)
Foxa2Hepatocyte nuclear factor 3-beta. (430 aa)
Gabrg2Gamma-aminobutyric acid receptor subunit gamma-2. (229 aa)
Slitrk5SLIT and NTRK-like protein 5. (781 aa)
I79_015056Neuronal acetylcholine receptor subunit alpha-7. (412 aa)
I79_014954Autophagy-related protein 7. (439 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (971 aa)
Unc79Protein unc-79-like. (223 aa)
Sez6lSeizure 6-like protein. (975 aa)
I79_014078Niemann-Pick C1 protein. (1137 aa)
Nr4a2Nuclear receptor subfamily 4 group A member 2. (598 aa)
Mecp2Methyl-CpG-binding protein 2. (203 aa)
I79_013707CREB-binding protein. (202 aa)
I79_013706CREB-binding protein. (759 aa)
Slc1a1Amino acid transporter. (492 aa)
I79_013598Disintegrin and metalloproteinase domain-containing protein 22. (744 aa)
I79_013437Nuclear receptor subfamily 4 group A member 3. (598 aa)
Scn1aSodium channel protein type 1 subunit alpha. (178 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
I79_012961SH3 and multiple ankyrin repeat domains protein 2. (1121 aa)
I79_012960SH3 and multiple ankyrin repeat domains protein 2. (436 aa)
Chd7Chromodomain-helicase-DNA-binding protein 7. (615 aa)
I79_012815Chromodomain-helicase-DNA-binding protein 7. (150 aa)
I79_012814Chromodomain-helicase-DNA-binding protein 7. (100 aa)
Shkbp1SH3KBP1-binding protein 1. (1696 aa)
Ppt1Palmitoyl-protein thioesterase 1. (306 aa)
Pcdh15Protocadherin-15. (1827 aa)
Nrxn1Neurexin-1-alpha. (849 aa)
AppAmyloid beta A4 protein. (433 aa)
I79_011902Paired box protein Pax-5. (386 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
Btbd9BTB/POZ domain-containing protein 9. (385 aa)
I79_011170BTB/POZ domain-containing protein 9. (247 aa)
Fgf14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
I79_010883Gastric inhibitory polypeptide. (205 aa)
NgfBeta-nerve growth factor; Belongs to the NGF-beta family. (112 aa)
I79_010620Alpha-synuclein; Belongs to the synuclein family. (166 aa)
Chl1Neural cell adhesion molecule L1-like protein. (54 aa)
CartptCocaine-and amphetamine-regulated transcript protein. (112 aa)
I79_010469Bardet-Biedl syndrome 2 protein-like. (594 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
Chrna4Neuronal acetylcholine receptor subunit alpha-4. (627 aa)
Ntsr1Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
Slitrk6SLIT and NTRK-like protein 6. (817 aa)
I79_009401Uncharacterized protein. (228 aa)
Tpgs1Tubulin polyglutamylase complex subunit 1. (291 aa)
Septin5Septin-5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (409 aa)
I79_009010Oxidation resistance protein 1. (54 aa)
Oxr1Oxidation resistance protein 1. (638 aa)
Bbs4Bardet-Biedl syndrome 4 protein-like. (125 aa)
I79_008980Bardet-Biedl syndrome 4 protein-like. (104 aa)
I79_008932Alpha-L-iduronidase. (625 aa)
Ndufs4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (171 aa)
Zfhx2Zinc finger homeobox protein 2. (497 aa)
I79_008565Zinc finger protein 409. (1891 aa)
I79_008360Voltage-dependent P/Q-type calcium channel subunit alpha-1A. (79 aa)
I79_008358Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (1774 aa)
Zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
Chrnb2Neuronal acetylcholine receptor subunit beta-2. (495 aa)
Cdk5Cell division protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
Gbx1Homeobox protein GBX-1. (202 aa)
Cntn2Contactin-2. (1008 aa)
I79_007529Cystine/glutamate transporter. (437 aa)
AsipAgouti-signaling protein. (131 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (533 aa)
I79_007313Neurexin-3-beta. (511 aa)
Eps8Epidermal growth factor receptor kinase substrate 8. (821 aa)
I79_007152tRNA (guanine(26)-N(2))-dimethyltransferase. (665 aa)
I79_007063Hepatocyte growth factor receptor. (1222 aa)
I79_006961Serine/threonine-protein kinase ULK4. (1552 aa)
Pcdh17Protocadherin-17. (1159 aa)
Grm2Metabotropic glutamate receptor 2. (916 aa)
I79_006562Voltage-dependent L-type calcium channel subunit alpha-1C. (1112 aa)
Kcnj10ATP-sensitive inward rectifier potassium channel 10. (379 aa)
Atp1a2Sodium/potassium-transporting ATPase subunit alpha-2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1194 aa)
NcstnNicastrin. (615 aa)
GlrbGlycine receptor subunit beta. (255 aa)
I79_006116Monoacylglycerol lipase ABHD12. (300 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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