STRINGSTRING
Dll1 Dll1 Mycl Mycl Zeb1 Zeb1 I79_011712 I79_011712 I79_011711 I79_011711 I79_011377 I79_011377 I79_011219 I79_011219 PRLR PRLR Sox2 Sox2 Gdnf Gdnf Btg1 Btg1 Zfp36 Zfp36 S1pr3 S1pr3 I79_010279 I79_010279 Spred1 Spred1 I79_010137 I79_010137 Nkx6-3 Nkx6-3 I79_010095 I79_010095 Cd109 Cd109 Akap11 Akap11 I79_009343 I79_009343 Apc Apc Cldn5 Cldn5 Id1 Id1 Fst Fst I79_008584 I79_008584 Osr1 Osr1 Srsf6 Srsf6 Bmp6 Bmp6 Hoxa7 Hoxa7 Zdhhc21 Zdhhc21 Bmp7 Bmp7 Apold1 Apold1 Cdkn1b Cdkn1b I79_007624 I79_007624 I79_007297 I79_007297 Serpine1 Serpine1 Cav1 Cav1 Lhx1 Lhx1 Ctnnb1 Ctnnb1 Mmp9 Mmp9 Ncoa3 Ncoa3 I79_006792 I79_006792 I79_006675 I79_006675 Spry1 Spry1 Foxj1 Foxj1 I79_014743 I79_014743 I79_015031 I79_015031 I79_015033 I79_015033 I79_015181 I79_015181 I79_015207 I79_015207 I79_015503 I79_015503 Cdkn1c Cdkn1c Wwtr1 Wwtr1 Kdf1 Kdf1 Sfn Sfn Prkch Prkch Dicer1 Dicer1 Gpsm3 Gpsm3 Tnf Tnf I79_016567 I79_016567 Sult2b1 Sult2b1 I79_016879 I79_016879 Foxp4 Foxp4 Lif Lif IL1B IL1B Gdf3 Gdf3 I79_017374 I79_017374 I79_017652 I79_017652 Fat4 Fat4 I79_017912 I79_017912 I79_018241 I79_018241 Xdh Xdh Foxj2 Foxj2 Rfx3 Rfx3 I79_018917 I79_018917 Wnt10b Wnt10b I79_019507 I79_019507 I79_019820 I79_019820 Hey2 Hey2 I79_020975 I79_020975 I79_021155 I79_021155 Acvrl1 Acvrl1 I79_021907 I79_021907 Vdr Vdr Pax8 Pax8 Errfi1 Errfi1 I79_022255 I79_022255 I79_023241 I79_023241 I79_023429 I79_023429 I79_023436 I79_023436 Krt84 Krt84 I79_023724 I79_023724 Ptch1 Ptch1 I79_024202 I79_024202 I79_024203 I79_024203 I79_024240 I79_024240 I79_024779 I79_024779 Commd5 Commd5 Dspp Dspp I79_025679 I79_025679 I79_025680 I79_025680 Wnt9b Wnt9b I79_025795 I79_025795 I79_026146 I79_026146 I79_026151 I79_026151 Tgfbr1 Tgfbr1 I79_006254 I79_006254 I79_006049 I79_006049 Nodal Nodal S1pr2 S1pr2 Keap1 Keap1 Ascl1 Ascl1 Cdh5 Cdh5 Med1 Med1 Sall1 Sall1 I79_005352 I79_005352 I79_004859 I79_004859 Zfp36l1 Zfp36l1 I79_003968 I79_003968 Tmem100 Tmem100 Msx2 Msx2 I79_003879 I79_003879 I79_003878 I79_003878 Spred2 Spred2 Pax6 Pax6 Pax4 Pax4 Smo Smo Ptch2 Ptch2 I79_002727 I79_002727 Ezh2 Ezh2 Mafg Mafg Vhl Vhl Vcl Vcl Ahi1 Ahi1 I79_001871 I79_001871 Trim16 Trim16 I79_001756 I79_001756 Sfrp4 Sfrp4 Six2 Six2 I79_001484 I79_001484 Tnfrsf1a Tnfrsf1a Tbx3 Tbx3 I79_000973 I79_000973 Tp63 Tp63 I79_000439 I79_000439 Jag1 Jag1 Foxp1 Foxp1 Gata3 Gata3 Ccnd1 Ccnd1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
MyclL-myc-1 proto-oncogene protein. (274 aa)
Zeb1Zinc finger E-box-binding homeobox 1. (1078 aa)
I79_011712Signal transducer and activator of transcription. (793 aa)
I79_011711Signal transducer and activator of transcription 5B. (274 aa)
I79_011377Grainyhead-like protein 2-like. (522 aa)
I79_011219Vitamin K-dependent protein C. (381 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (605 aa)
Sox2Transcription factor SOX-2. (273 aa)
GdnfGlial cell line-derived neurotrophic factor. (160 aa)
Btg1Protein BTG1. (97 aa)
Zfp36Tristetraproline. (315 aa)
S1pr3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa)
I79_010279Epithelial splicing regulatory protein 1. (677 aa)
Spred1Sprouty-related, EVH1 domain-containing protein 1. (370 aa)
I79_010137Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (262 aa)
Nkx6-3Homeobox protein Nkx-6.3. (262 aa)
I79_010095Inhibitor of nuclear factor kappa-B kinase subunit beta. (408 aa)
Cd109CD109 antigen. (1443 aa)
Akap11A-kinase anchor protein 11. (1892 aa)
I79_009343N-myc proto-oncogene protein. (316 aa)
ApcAdenomatous polyposis coli protein. (2488 aa)
Cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (238 aa)
Id1DNA-binding protein inhibitor ID-1. (157 aa)
FstFollistatin. (316 aa)
I79_008584Krueppel-like factor 7. (301 aa)
Osr1Protein odd-skipped-related 1. (266 aa)
Srsf6Splicing factor, arginine/serine-rich 6. (210 aa)
Bmp6Bone morphogenetic protein 6. (296 aa)
Hoxa7Homeobox protein Hox-A7. (112 aa)
Zdhhc21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
Apold1Apolipoprotein L domain-containing protein 1. (88 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (198 aa)
I79_007624Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1071 aa)
I79_007297Plasminogen activator inhibitor 1; Belongs to the serpin family. (108 aa)
Serpine1Plasminogen activator inhibitor 1; Belongs to the serpin family. (270 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Lhx1LIM/homeobox protein Lhx1. (84 aa)
Ctnnb1Catenin beta-1. (781 aa)
Mmp9Matrix metalloproteinase-9. (710 aa)
Ncoa3Nuclear receptor coactivator 3. (1211 aa)
I79_006792DUF1518 domain-containing protein. (200 aa)
I79_006675Secreted frizzled-related protein 3. (286 aa)
Spry1Protein sprouty-like 1. (313 aa)
Foxj1Forkhead box protein J1. (421 aa)
I79_014743Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1071 aa)
I79_015031ATP-binding cassette sub-family A member 12. (892 aa)
I79_015033Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
I79_01518114-3-3 protein sigma; Belongs to the 14-3-3 family. (249 aa)
I79_01520725-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (232 aa)
I79_015503Transcription factor HES-1. (92 aa)
Cdkn1cCyclin-dependent kinase inhibitor 1C. (217 aa)
Wwtr1WW domain-containing transcription regulator protein 1. (395 aa)
Kdf1Uncharacterized protein C1orf172-like. (397 aa)
Sfn14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
PrkchProtein kinase C eta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (635 aa)
Dicer1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
Gpsm3Neurogenic locus notch-like protein 4. (1797 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
I79_016567Zinc finger E-box-binding homeobox 2. (1282 aa)
Sult2b1Sulfotransferase; Belongs to the sulfotransferase 1 family. (239 aa)
I79_016879Alpha-adducin. (735 aa)
Foxp4Forkhead box protein P4. (685 aa)
LifLeukemia inhibitory factor-like protein. (158 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Gdf3Growth/differentiation factor 3. (361 aa)
I79_017374ATP-binding cassette sub-family A member 12. (506 aa)
I79_017652Grainyhead-like protein 1-like. (447 aa)
Fat4Protocadherin Fat 4. (5152 aa)
I79_017912Nuclear mitotic apparatus protein 1; Belongs to the transient receptor (TC 1.A.4) family. (3026 aa)
I79_018241Serine/threonine-protein kinase PRKX. (388 aa)
XdhXanthine dehydrogenase/oxidase. (1332 aa)
Foxj2Forkhead box protein J2. (573 aa)
Rfx3Transcription factor RFX3. (298 aa)
I79_018917Transcription factor RFX3. (70 aa)
Wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
I79_019507Prominin-1. (565 aa)
I79_019820Keratin, type I cuticular Ha6; Belongs to the intermediate filament family. (467 aa)
Hey2Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
I79_020975Deleted in malignant brain tumors 1 protein. (964 aa)
I79_021155Paired box protein Pax-2. (503 aa)
Acvrl1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (776 aa)
I79_021907Transcription factor MafF. (154 aa)
VdrVitamin D3 receptor. (372 aa)
Pax8Paired box protein Pax-8. (452 aa)
Errfi1ERBB receptor feedback inhibitor 1. (460 aa)
I79_022255Adherens junction-associated protein 1. (281 aa)
I79_023241Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (558 aa)
I79_023429Forkhead box protein P4. (631 aa)
I79_023436Forkhead box protein P4. (104 aa)
Krt84Keratin, type II cuticular Hb4; Belongs to the intermediate filament family. (602 aa)
I79_023724Adherens junction-associated protein 1. (134 aa)
Ptch1Protein patched-like 1. (1114 aa)
I79_024202Sal-like protein 1. (825 aa)
I79_024203Sal-like protein 1. (121 aa)
I79_024240Forkhead box protein N1. (293 aa)
I79_024779Homeobox protein Nkx-6.1. (99 aa)
Commd5COMM domain-containing protein 5. (224 aa)
DsppDentin sialophosphoprotein. (859 aa)
I79_025679Forkhead box protein P4. (346 aa)
I79_025680Forkhead box protein P4. (206 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
I79_025795Vitamin D3 receptor. (86 aa)
I79_026146ETS translocation variant 4. (95 aa)
I79_026151ETS translocation variant 4. (69 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006049Core histone macro-H2A.2. (393 aa)
NodalNodal. (309 aa)
S1pr2Sphingosine 1-phosphate receptor 2. (352 aa)
Keap1Kelch-like ECH-associated protein 1. (624 aa)
Ascl1Achaete-scute-like 1. (140 aa)
Cdh5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (763 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
Sall1Sal-like protein 1. (1294 aa)
I79_005352Sphingosine-1-phosphate phosphatase 1. (241 aa)
I79_004859Protein atonal-like 1. (293 aa)
Zfp36l1Butyrate response factor 1. (338 aa)
I79_003968Vascular endothelial zinc finger 1. (361 aa)
Tmem100Transmembrane protein 100. (134 aa)
Msx2Homeobox protein MSX-2. (267 aa)
I79_003879Core histone macro-H2A.1. (155 aa)
I79_003878Histone H2A; Belongs to the histone H2A family. (242 aa)
Spred2Sprouty-related, EVH1 domain-containing protein 2. (415 aa)
Pax6Paired box protein Pax-6. (544 aa)
Pax4Paired box protein Pax-4. (231 aa)
SmoSmoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
Ptch2Protein patched-like 2. (1176 aa)
I79_002727Arachidonate 15-lipoxygenase type II. (407 aa)
Ezh2Histone-lysine N-methyltransferase EZH2. (746 aa)
MafgTranscription factor MafG. (162 aa)
VhlVon Hippel-Lindau disease tumor suppressor. (134 aa)
VclVinculin. (1143 aa)
Ahi1Jouberin. (988 aa)
I79_001871Transcription factor Ovo-like 2. (213 aa)
Trim16Tripartite motif-containing protein 16. (274 aa)
I79_001756Tripartite motif-containing protein 16. (197 aa)
Sfrp4Secreted frizzled-related protein 4. (348 aa)
Six2Homeobox protein SIX2. (299 aa)
I79_00148465 kDa Yes-associated protein. (257 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (355 aa)
Tbx3T-box transcription factor TBX3. (709 aa)
I79_000973Transcription factor SOX-10. (360 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (642 aa)
I79_000439Phosphoinositide phospholipase C. (949 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
Foxp1Forkhead box protein P1. (696 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
Ccnd1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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