(32 nodes) Cortical actin cytoskeleton organization network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_021852	Formin-like protein 2. (962 aa)
	I79_022091	Protein kinase C delta-binding protein. (268 aa)
	Fmnl3	Formin-like protein 3. (985 aa)
	Strip1	Protein FAM40A. (555 aa)
	Arf6	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	Fhod1	FH1/FH2 domain-containing protein 1. (1182 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	Racgap1	Rac GTPase-activating protein 1. (628 aa)
	Vil1	Villin-1. (827 aa)
	Ezr	Ezrin. (586 aa)
	I79_014743	Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1071 aa)
	I79_014068	Band 4.1-like protein 3. (912 aa)
	I79_012132	Talin-1; Belongs to the tropomyosin family. (1849 aa)
	I79_011620	Formin-like protein 1. (1012 aa)
	I79_010095	Inhibitor of nuclear factor kappa-B kinase subunit beta. (408 aa)
	Akap11	A-kinase anchor protein 11. (1892 aa)
	Plek	Pleckstrin. (327 aa)
	Calr	Calreticulin. (417 aa)
	Rab13	Ras-related protein Rab-13. (199 aa)
	Cdk5	Cell division protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	I79_007624	Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1071 aa)
	I79_007116	FH1/FH2 domain-containing protein 3. (995 aa)
	I79_006673	Nck-associated protein 1. (951 aa)
	Pdcd6ip	Programmed cell death 6-interacting protein. (867 aa)
	I79_004172	Protein 4.1. (773 aa)
	Llgl1	Lethal(2) giant larvae protein-like 1. (754 aa)
	Pls1	Plastin-1. (1002 aa)
	Anln	Actin-binding protein anillin. (1121 aa)
	Epb41l2	Band 4.1-like protein 2. (1032 aa)
	I79_019038	Nck-associated protein 1-like. (1065 aa)
	Rtkn	Rhotekin. (552 aa)
	Rhoq	Rho-related GTP-binding protein RhoQ. (126 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Akap11	I79_011620	G3HGS9	G3HLN0	A-kinase anchor protein 11.	Formin-like protein 1.	0.673
Anln	I79_007624	G3I0R8	G3HB11	Actin-binding protein anillin.	Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.539
Anln	I79_014743	G3I0R8	G3HUX3	Actin-binding protein anillin.	Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.539
Anln	Racgap1	G3I0R8	G3HX62	Actin-binding protein anillin.	Rac GTPase-activating protein 1.	0.903
Anln	Rhoq	G3I0R8	G3I8N3	Actin-binding protein anillin.	Rho-related GTP-binding protein RhoQ.	0.484
Anln	Rtkn	G3I0R8	G3I7V9	Actin-binding protein anillin.	Rhotekin.	0.513
Arf6	Plek	G3IMU0	G3HEF8	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Pleckstrin.	0.502
Epb41l2	I79_004172	G3I2D8	G3H1Y0	Band 4.1-like protein 2.	Protein 4.1.	0.406
Epb41l2	I79_014068	G3I2D8	G3HT50	Band 4.1-like protein 2.	Band 4.1-like protein 3.	0.607
Ezr	I79_004172	G3HWC3	G3H1Y0	Ezrin.	Protein 4.1.	0.813
Ezr	I79_012132	G3HWC3	G3HN02	Ezrin.	Talin-1; Belongs to the tropomyosin family.	0.468
Ezr	Plek	G3HWC3	G3HEF8	Ezrin.	Pleckstrin.	0.447
Ezr	Pls1	G3HWC3	G3GSZ0	Ezrin.	Plastin-1.	0.643
Fhod1	I79_004172	G3HZL3	G3H1Y0	FH1/FH2 domain-containing protein 1.	Protein 4.1.	0.638
Fmnl3	Rhoq	G3IFG5	G3I8N3	Formin-like protein 3.	Rho-related GTP-binding protein RhoQ.	0.515
I79_004172	Epb41l2	G3H1Y0	G3I2D8	Protein 4.1.	Band 4.1-like protein 2.	0.406
I79_004172	Ezr	G3H1Y0	G3HWC3	Protein 4.1.	Ezrin.	0.813
I79_004172	Fhod1	G3H1Y0	G3HZL3	Protein 4.1.	FH1/FH2 domain-containing protein 1.	0.638
I79_004172	I79_014068	G3H1Y0	G3HT50	Protein 4.1.	Band 4.1-like protein 3.	0.476
I79_006673	I79_019038	G3H8H3	G3I6C2	Nck-associated protein 1.	Nck-associated protein 1-like.	0.709