STRINGSTRING
I79_013964 I79_013964 I79_014474 I79_014474 Gli3 Gli3 Stat6 Stat6 Agap2 Agap2 I79_015381 I79_015381 Ncor2 Ncor2 Sostdc1 Sostdc1 Hif1a Hif1a Chuk Chuk Gpsm3 Gpsm3 I79_016800 I79_016800 Slc29a2 Slc29a2 I79_017833 I79_017833 I79_017861 I79_017861 I79_018050 I79_018050 I79_018051 I79_018051 I79_018052 I79_018052 I79_018053 I79_018053 CgPICR_009833 CgPICR_009833 I79_018055 I79_018055 I79_018056 I79_018056 Xdh Xdh Btrc Btrc Lrp5 Lrp5 I79_026151 I79_026151 I79_026146 I79_026146 I79_025795 I79_025795 I79_025355 I79_025355 I79_025170 I79_025170 Capn1 Capn1 I79_024593 I79_024593 I79_024533 I79_024533 Tph1 Tph1 Irs2 Irs2 I79_024314 I79_024314 Fgfr2 Fgfr2 Ptch1 Ptch1 I79_024048 I79_024048 Csf1 Csf1 Ar Ar Bsx Bsx Hk2 Hk2 Arhgap35 Arhgap35 Jak2 Jak2 I79_022023 I79_022023 Vdr Vdr Irs1 Irs1 I79_021564 I79_021564 Arhgap5 Arhgap5 Wnt7b Wnt7b Tgfa Tgfa Areg Areg Tgfb1 Tgfb1 Epha2 Epha2 I79_019286 I79_019286 COX2 COX2 Gja1 Gja1 Ccnd1 Ccnd1 Foxb1 Foxb1 I79_000224 I79_000224 Foxf1 Foxf1 I79_000271 I79_000271 Umps Umps I79_000658 I79_000658 I79_000973 I79_000973 I79_001073 I79_001073 Tbx3 Tbx3 Rplp0 Rplp0 Phb2 Phb2 Wnt5a Wnt5a I79_001487 I79_001487 Tgfbr2 Tgfbr2 Lbh Lbh Msx1 Msx1 I79_002157 I79_002157 I79_002357 I79_002357 Fasn Fasn Src Src I79_002693 I79_002693 Smo Smo Csmd1 Csmd1 I79_003312 I79_003312 I79_003468 I79_003468 Gli2 Gli2 Msx2 Msx2 Znf703 Znf703 Orai1 Orai1 Irf6 Irf6 Kdm5b Kdm5b Lats1 Lats1 Igfbp5 Igfbp5 I79_005331 I79_005331 Med1 Med1 Igf1 Igf1 I79_006254 I79_006254 I79_006442 I79_006442 I79_006650 I79_006650 Mst1 Mst1 I79_006792 I79_006792 Ncoa3 Ncoa3 I79_006881 I79_006881 Tbx2 Tbx2 Cav1 Cav1 Wnt2 Wnt2 I79_007089 I79_007089 I79_007090 I79_007090 I79_007573 I79_007573 I79_007641 I79_007641 Lrp6 Lrp6 CgPICR_020542 CgPICR_020542 Tfap2c Tfap2c Zbtb7b Zbtb7b Pygo2 Pygo2 I79_008089 I79_008089 I79_008319 I79_008319 Hoxa9 Hoxa9 I79_008756 I79_008756 Pml Pml Nr3c1 Nr3c1 Tgfb3 Tgfb3 I79_009500 I79_009500 Iqgap3 Iqgap3 Nrg3 Nrg3 Tnfsf11 Tnfsf11 Gpat4 Gpat4 Atp7b Atp7b I79_010077 I79_010077 I79_010136 I79_010136 Robo1 Robo1 I79_010159 I79_010159 Wnt4 Wnt4 I79_010613 I79_010613 I79_010622 I79_010622 Lrrc1 Lrrc1 I79_010839 I79_010839 I79_010864 I79_010864 PRLR PRLR I79_011192 I79_011192 Igf1r Igf1r I79_011711 I79_011711 I79_011712 I79_011712 I79_011789 I79_011789 I79_011834 I79_011834 Brca2 Brca2 I79_011936 I79_011936 I79_011937 I79_011937 I79_012244 I79_012244 Atp7a Atp7a I79_013032 I79_013032 Ddr1 Ddr1 I79_013712 I79_013712
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_01396460S acidic ribosomal protein P0. (153 aa)
I79_014474Cyclic AMP-responsive element-binding protein 1. (325 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
Stat6Signal transducer and activator of transcription. (844 aa)
Agap2Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2. (829 aa)
I79_015381Protein scribble-like. (789 aa)
Ncor2Nuclear receptor corepressor 2. (2530 aa)
Sostdc1Sclerostin domain-containing protein 1. (193 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha. (647 aa)
Gpsm3Neurogenic locus notch-like protein 4. (1797 aa)
I79_016800Cytochrome P450 19A1; Belongs to the cytochrome P450 family. (436 aa)
Slc29a2Equilibrative nucleoside transporter 2. (458 aa)
I79_017833Lymphoid enhancer-binding factor 1. (276 aa)
I79_017861Solute carrier family 12 member 2. (706 aa)
I79_018050Prolactin-3D4. (172 aa)
I79_018051Prolactin. (225 aa)
I79_018052Prolactin-3D4. (185 aa)
I79_018053Prolactin-3B1. (114 aa)
CgPICR_009833Prolactin-3B1. (216 aa)
I79_018055Prolactin-6A1. (146 aa)
I79_018056Prolactin-3D4. (83 aa)
XdhXanthine dehydrogenase/oxidase. (1332 aa)
BtrcF-box/WD repeat-containing protein 1A. (488 aa)
Lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1608 aa)
I79_026151ETS translocation variant 4. (69 aa)
I79_026146ETS translocation variant 4. (95 aa)
I79_025795Vitamin D3 receptor. (86 aa)
I79_025355Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (325 aa)
I79_025170Slit-like 2 protein. (345 aa)
Capn1Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (740 aa)
I79_024593Uncharacterized protein. (194 aa)
I79_024533Tryptophan 5-hydroxylase 1. (131 aa)
Tph1Tryptophan 5-hydroxylase 1. (115 aa)
Irs2Insulin receptor substrate 2. (465 aa)
I79_024314Paired box protein Pax-3. (301 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
Ptch1Protein patched-like 1. (1114 aa)
I79_024048Paired box protein Pax-3. (324 aa)
Csf1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (552 aa)
ArAndrogen receptor. (517 aa)
BsxBrain-specific homeobox protein-like. (89 aa)
Hk2Hexokinase-2. (704 aa)
Arhgap35Glucocorticoid receptor DNA-binding factor 1. (1499 aa)
Jak2Tyrosine-protein kinase. (1122 aa)
I79_022023Arginase-1; Belongs to the arginase family. (281 aa)
VdrVitamin D3 receptor. (372 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
Arhgap5Rho GTPase-activating protein 5. (1502 aa)
Wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
TgfaProtransforming growth factor alpha. (211 aa)
AregAmphiregulin. (230 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Epha2Ephrin type-A receptor 2. (942 aa)
I79_019286Androgen receptor. (295 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa)
Gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
Ccnd1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
Foxb1Forkhead box protein B1. (325 aa)
I79_000224Adenine phosphoribosyltransferase. (192 aa)
Foxf1Forkhead box protein F1. (320 aa)
I79_000271Calcium-transporting ATPase type 2C member 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (875 aa)
UmpsUridine 5'-monophosphate synthase. (480 aa)
I79_000658Kalirin. (2681 aa)
I79_000973Transcription factor SOX-10. (360 aa)
I79_001073C-C motif chemokine. (72 aa)
Tbx3T-box transcription factor TBX3. (709 aa)
Rplp060S acidic ribosomal protein P0. (272 aa)
Phb2Prohibitin-2. (396 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
I79_001487Progesterone receptor. (741 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LbhProtein LBH. (88 aa)
Msx1Homeobox protein MSX-1. (261 aa)
I79_002157Phosphotransferase. (266 aa)
I79_002357Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1295 aa)
FasnFatty acid synthase. (2503 aa)
SrcTyrosine-protein kinase. (536 aa)
I79_002693Netrin-1. (252 aa)
SmoSmoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
Csmd1CUB and sushi domain-containing protein 1. (106 aa)
I79_003312CUB and sushi domain-containing protein 1. (3110 aa)
I79_003468Bcl-2-like protein 11. (141 aa)
Gli2Zinc finger protein GLI2. (1547 aa)
Msx2Homeobox protein MSX-2. (267 aa)
Znf703Zinc finger protein 703. (143 aa)
Orai1Calcium release-activated calcium channel protein 1. (237 aa)
Irf6Interferon regulatory factor 6. (467 aa)
Kdm5bLysine-specific demethylase 5B. (748 aa)
Lats1Serine/threonine-protein kinase LATS1. (1130 aa)
Igfbp5Insulin-like growth factor-binding protein 5. (271 aa)
I79_005331Receptor tyrosine-protein kinase erbB-4. (480 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
Igf1Insulin-like growth factor I. (75 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006442Relaxin receptor 1. (770 aa)
I79_006650Hepatocyte growth factor-like protein. (93 aa)
Mst1Hepatocyte growth factor-like protein. (88 aa)
I79_006792DUF1518 domain-containing protein. (200 aa)
Ncoa3Nuclear receptor coactivator 3. (1211 aa)
I79_006881CUB and sushi domain-containing protein 2. (3527 aa)
Tbx2T-box transcription factor TBX2. (234 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
I79_007089Receptor tyrosine-protein kinase erbB-4. (225 aa)
I79_007090Receptor tyrosine-protein kinase erbB-4. (182 aa)
I79_00757360S acidic ribosomal protein P0. (220 aa)
I79_007641Low-density lipoprotein receptor-related protein 6. (543 aa)
Lrp6Low-density lipoprotein receptor-related protein 6. (565 aa)
CgPICR_020542Nucleoside diphosphate kinase. (152 aa)
Tfap2cTranscription factor AP-2 gamma. (463 aa)
Zbtb7bZinc finger and BTB domain-containing protein 7B. (543 aa)
Pygo2Pygopus-like 2. (405 aa)
I79_008089Equilibrative nucleoside transporter 1. (184 aa)
I79_008319Zinc finger protein 157. (381 aa)
Hoxa9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (271 aa)
I79_00875660S acidic ribosomal protein P0. (274 aa)
PmlPutative transcription factor PML. (540 aa)
Nr3c1Glucocorticoid receptor. (748 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
I79_009500Mitogen-activated protein kinase 1. (68 aa)
Iqgap3Ras GTPase-activating-like protein IQGAP3. (1633 aa)
Nrg3Pro-neuregulin-3, membrane-bound isoform. (153 aa)
Tnfsf11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (199 aa)
Gpat4Glycerol-3-phosphate acyltransferase 4. (456 aa)
Atp7bCopper-transporting ATPase 2. (796 aa)
I79_010077Copper-transporting ATPase 2. (660 aa)
I79_010136Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (230 aa)
Robo1Roundabout-like 1. (129 aa)
I79_010159Roundabout-like 1. (1362 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
I79_010613Transcription factor AP-2 gamma. (236 aa)
I79_010622Leucine-rich repeat-containing protein 1. (119 aa)
Lrrc1Leucine-rich repeat-containing protein 1. (167 aa)
I79_010839Eukaryotic translation initiation factor 2-alpha kinase 3. (783 aa)
I79_010864Growth hormone-releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (372 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (605 aa)
I79_01119260S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (280 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
I79_011711Signal transducer and activator of transcription 5B. (274 aa)
I79_011712Signal transducer and activator of transcription. (793 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
I79_011834Breast cancer type 2 susceptibility protein-like. (143 aa)
Brca2Breast cancer type 2 susceptibility protein-like. (3008 aa)
I79_011936Prolactin-7A2. (148 aa)
I79_011937Prolactin-5A1. (252 aa)
I79_01224460S acidic ribosomal protein P0. (189 aa)
Atp7aCopper-transporting ATPase 1. (1457 aa)
I79_013032Peptidyl-glycine alpha-amidating monooxygenase B. (851 aa)
Ddr1Epithelial discoidin domain-containing receptor 1 isoform 1. (910 aa)
I79_013712Suppressor of cytokine signaling 2. (198 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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