STRINGSTRING
AARS-2 AARS-2 Aldh1a2 Aldh1a2 Wnt7a Wnt7a Nr2c2 Nr2c2 Usp9x Usp9x Gart Gart Sstr2 Sstr2 I79_001030 I79_001030 Abat Abat Foxp2 Foxp2 Ahi1 Ahi1 Gnpat Gnpat I79_002357 I79_002357 Ezh2 Ezh2 I79_002457 I79_002457 Pdss2 Pdss2 Myh10 Myh10 Atp1b2 Atp1b2 Arl13b Arl13b Mdk Mdk Prox1 Prox1 I79_000120 I79_000120 Smo Smo Pax6 Pax6 Dlc1 Dlc1 I79_003644 I79_003644 Rpgrip1l Rpgrip1l I79_003784 I79_003784 Gli2 Gli2 Nog Nog Sema4c Sema4c Atf2 Atf2 Kdm2b Kdm2b I79_004244 I79_004244 I79_004263 I79_004263 Dixdc1 Dixdc1 I79_004445 I79_004445 Plxna2 Plxna2 Ckb Ckb Kif14 Kif14 Grid2 Grid2 Atrn Atrn I79_005220 I79_005220 Herc1 Herc1 I79_005393 I79_005393 I79_005394 I79_005394 Ptf1a Ptf1a Znf423 Znf423 Cbln1 Cbln1 I79_005672 I79_005672 Hoxb2 Hoxb2 Hoxb1 Hoxb1 I79_005719 I79_005719 Ascl1 Ascl1 Smarca4 Smarca4 Neurog3 Neurog3 I79_006225 I79_006225 Ncstn Ncstn Pcnt Pcnt Ctnnb1 Ctnnb1 Lhx1 Lhx1 Smad1 Smad1 I79_007641 I79_007641 Lrp6 Lrp6 Cdk5 Cdk5 Bmp7 Bmp7 Gba Gba Nfib Nfib Ulk1 Ulk1 Ptprs Ptprs I79_008197 I79_008197 I79_008358 I79_008358 I79_008360 I79_008360 Ephb1 Ephb1 Hoxa1 Hoxa1 Hoxa2 Hoxa2 Neurod1 Neurod1 I79_008642 I79_008642 Nav2 Nav2 B4galt2 B4galt2 Crkl Crkl Smad9 Smad9 Gata2 Gata2 Ephb2 Ephb2 Znf365 Znf365 I79_010622 I79_010622 Lrrc1 Lrrc1 I79_010773 I79_010773 I79_010954 I79_010954 Cplane1 Cplane1 Igf1r Igf1r Cbs Cbs Hap1 Hap1 Kat2a Kat2a Naglu Naglu Nrxn1 Nrxn1 I79_012148 I79_012148 Psen1 Psen1 Coq8b Coq8b Dll1 Dll1 Atp7a Atp7a I79_012761 I79_012761 Lmx1a Lmx1a Ttc21b Ttc21b CLP1 CLP1 Otx2 Otx2 Mecp2 Mecp2 Sez6l Sez6l Crk Crk Mafb Mafb Lpar1 Lpar1 I79_014954 I79_014954 I79_015027 I79_015027 I79_015028 I79_015028 Abl2 Abl2 Gli1 Gli1 I79_015319 I79_015319 I79_015381 I79_015381 Wls Wls I79_015503 I79_015503 I79_015849 I79_015849 Foxa2 Foxa2 Ldb1 Ldb1 Zbtb18 Zbtb18 I79_016282 I79_016282 Itgb1 Itgb1 Psmg1 Psmg1 I79_016797 I79_016797 Cul5 Cul5 Klhl1 Klhl1 I79_017126 I79_017126 Tbr1 Tbr1 Kcnc1 Kcnc1 Atic Atic Psap Psap I79_017833 I79_017833 Cend1 Cend1 Sdf4 Sdf4 Sez6l2 Sez6l2 Sptbn2 Sptbn2 I79_018396 I79_018396 Agtr2 Agtr2 Pfdn1 Pfdn1 Arcn1 Arcn1 Hnf1b Hnf1b Wnt1 Wnt1 Lhx5 Lhx5 Slc25a46 Slc25a46 I79_019287 I79_019287 Atf5 Atf5 Hnrnpd Hnrnpd I79_019429 I79_019429 Sstr1 Sstr1 I79_019616 I79_019616 Rbfox2 Rbfox2 I79_019981 I79_019981 Rere Rere I79_020166 I79_020166 I79_020248 I79_020248 I79_020650 I79_020650 Agtpbp1 Agtpbp1 Flna Flna I79_021503 I79_021503 I79_021938 I79_021938 I79_022050 I79_022050 Fzd4 Fzd4 I79_022316 I79_022316 I79_022486 I79_022486 Gbx2 Gbx2 I79_022599 I79_022599 Rora Rora I79_022712 I79_022712 Abl1 Abl1 I79_023135 I79_023135 Ptbp2 Ptbp2 I79_024010 I79_024010 Hes3 Hes3 I79_024341 I79_024341 Sstr3 Sstr3 I79_024959 I79_024959 I79_025312 I79_025312 I79_025316 I79_025316 Serpine2 Serpine2 I79_025459 I79_025459 I79_025510 I79_025510 I79_025513 I79_025513 Map2k1 Map2k1 Egr2 Egr2 I79_025783 I79_025783 NADH4 NADH4 COX1 COX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AARS-2Alanyl-tRNA synthetase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
Aldh1a2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (460 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (282 aa)
Nr2c2Nuclear receptor subfamily 2 group C member 2. (596 aa)
Usp9xPutative ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2558 aa)
GartTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
Sstr2Somatostatin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
I79_001030Myosin-XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1503 aa)
Abat4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
Foxp2Forkhead box protein P2. (492 aa)
Ahi1Jouberin. (988 aa)
GnpatDihydroxyacetone phosphate acyltransferase. (669 aa)
I79_002357Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1295 aa)
Ezh2Histone-lysine N-methyltransferase EZH2. (746 aa)
I79_002457Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (134 aa)
Pdss2Decaprenyl-diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (401 aa)
Myh10Myosin-10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1976 aa)
Atp1b2Sodium/potassium-transporting ATPase subunit beta-2. (436 aa)
Arl13bADP-ribosylation factor-like protein 13B. (422 aa)
MdkMidkine. (160 aa)
Prox1Prospero homeobox protein 1. (738 aa)
I79_000120Bone morphogenetic protein 5. (260 aa)
SmoSmoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
Pax6Paired box protein Pax-6. (544 aa)
Dlc1Rho GTPase-activating protein 7. (1082 aa)
I79_003644Rho GTPase-activating protein 7. (409 aa)
Rpgrip1lProtein fantom. (1265 aa)
I79_003784Tau-tubulin kinase 2. (1175 aa)
Gli2Zinc finger protein GLI2. (1547 aa)
NogNoggin. (117 aa)
Sema4cSemaphorin-4C; Belongs to the semaphorin family. (834 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2. (487 aa)
Kdm2bLysine-specific demethylase 2B. (1305 aa)
I79_004244Tyrosine-protein phosphatase non-receptor type 11. (583 aa)
I79_004263Ataxin-2. (904 aa)
Dixdc1Dixin. (689 aa)
I79_004445Plexin-A2. (467 aa)
Plxna2Plexin-A2. (1359 aa)
CkbCreatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. (203 aa)
Kif14Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1633 aa)
Grid2Glutamate receptor delta-2 subunit. (211 aa)
AtrnAttractin. (1062 aa)
I79_005220Serine/threonine-protein kinase Nek10. (1120 aa)
Herc1Putative E3 ubiquitin-protein ligase HERC1. (1016 aa)
I79_005393Putative E3 ubiquitin-protein ligase HERC1. (501 aa)
I79_005394Putative E3 ubiquitin-protein ligase HERC1. (328 aa)
Ptf1aPancreas transcription factor 1 subunit alpha. (152 aa)
Znf423Zinc finger protein 423. (1224 aa)
Cbln1Cerebellin-1. (172 aa)
I79_005672Homeobox protein Hox-B3. (174 aa)
Hoxb2Homeobox protein Hox-B2. (407 aa)
Hoxb1Homeobox protein Hox-B1. (297 aa)
I79_005719Neurogenic differentiation factor 2. (352 aa)
Ascl1Achaete-scute-like 1. (140 aa)
Smarca4Putative global transcription activator SNF2L4. (1614 aa)
Neurog3Neurogenin-3. (214 aa)
I79_006225Sonic hedgehog protein. (226 aa)
NcstnNicastrin. (615 aa)
PcntPericentrin. (3034 aa)
Ctnnb1Catenin beta-1. (781 aa)
Lhx1LIM/homeobox protein Lhx1. (84 aa)
Smad1Mothers against decapentaplegic-like 1. (232 aa)
I79_007641Low-density lipoprotein receptor-related protein 6. (543 aa)
Lrp6Low-density lipoprotein receptor-related protein 6. (565 aa)
Cdk5Cell division protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
GbaGlucosylceramidase. (515 aa)
NfibNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (561 aa)
Ulk1Serine/threonine-protein kinase ULK1. (999 aa)
PtprsReceptor-type tyrosine-protein phosphatase S. (889 aa)
I79_008197Receptor-type tyrosine-protein phosphatase S. (515 aa)
I79_008358Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (1774 aa)
I79_008360Voltage-dependent P/Q-type calcium channel subunit alpha-1A. (79 aa)
Ephb1Ephrin type-B receptor 1. (737 aa)
Hoxa1Homeobox protein Hox-A1. (334 aa)
Hoxa2Homeobox protein Hox-A2. (76 aa)
Neurod1Neurogenic differentiation factor. (355 aa)
I79_008642Homeobox protein OTX1. (339 aa)
Nav2Neuron navigator 2. (2028 aa)
B4galt2Beta-1,4-galactosyltransferase 2. (369 aa)
CrklCrk-like protein. (303 aa)
Smad9Mothers against decapentaplegic homolog. (465 aa)
Gata2Endothelial transcription factor GATA-2. (480 aa)
Ephb2Ephrin type-B receptor 2. (1018 aa)
Znf365Protein ZNF365. (313 aa)
I79_010622Leucine-rich repeat-containing protein 1. (119 aa)
Lrrc1Leucine-rich repeat-containing protein 1. (167 aa)
I79_010773Protein Smaug-like 2. (717 aa)
I79_010954Uncharacterized protein C5orf42. (531 aa)
Cplane1Uncharacterized protein C5orf42. (563 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
CbsCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (561 aa)
Hap1Huntingtin-associated protein 1. (602 aa)
Kat2aHistone acetyltransferase KAT2A. (663 aa)
NagluAlpha-N-acetylglucosaminidase. (740 aa)
Nrxn1Neurexin-1-alpha. (849 aa)
I79_012148Transmembrane protein C9orf144B-like. (1407 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
Coq8bUncharacterized aarF domain-containing protein kinase 4. (693 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
Atp7aCopper-transporting ATPase 1. (1457 aa)
I79_012761LIM homeobox transcription factor 1-alpha. (88 aa)
Lmx1aLIM homeobox transcription factor 1-alpha. (333 aa)
Ttc21bTetratricopeptide repeat protein 21B. (1315 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
Otx2Homeobox protein OTX2. (289 aa)
Mecp2Methyl-CpG-binding protein 2. (203 aa)
Sez6lSeizure 6-like protein. (975 aa)
CrkProto-oncogene C-crk. (327 aa)
MafbTranscription factor MafB. (317 aa)
Lpar1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
I79_014954Autophagy-related protein 7. (439 aa)
I79_015027Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. (93 aa)
I79_015028Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. (95 aa)
Abl2Tyrosine-protein kinase. (1167 aa)
Gli1Zinc finger protein GLI1. (1104 aa)
I79_015319Cyclin-dependent kinase 5 activator 2. (97 aa)
I79_015381Protein scribble-like. (789 aa)
WlsIntegral membrane protein GPR177. (166 aa)
I79_015503Transcription factor HES-1. (92 aa)
I79_015849Putative tubulin polyglutamylase TTLL1. (345 aa)
Foxa2Hepatocyte nuclear factor 3-beta. (430 aa)
Ldb1LIM domain-binding protein 1. (375 aa)
Zbtb18Zinc finger protein 238. (522 aa)
I79_016282DNA repair protein XRCC1. (460 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
Psmg1Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2. (289 aa)
I79_016797Dual specificity mitogen-activated protein kinase kinase 1. (129 aa)
Cul5Cullin-5; Belongs to the cullin family. (780 aa)
Klhl1Kelch-like protein 1. (180 aa)
I79_017126T-box brain protein 1. (74 aa)
Tbr1T-box brain protein 1. (231 aa)
Kcnc1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (386 aa)
AticBifunctional purine biosynthesis protein PURH. (592 aa)
PsapSulfated glycoprotein 1. (249 aa)
I79_017833Lymphoid enhancer-binding factor 1. (276 aa)
Cend1Cell cycle exit and neuronal differentiation protein 1. (149 aa)
Sdf445 kDa calcium-binding protein. (355 aa)
Sez6l2Seizure 6-like protein 2. (401 aa)
Sptbn2Spectrin beta chain, brain 2. (56 aa)
I79_018396Spectrin beta chain, brain 2. (81 aa)
Agtr2Type-2 angiotensin II receptor-like protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
Pfdn1Prefoldin subunit 1. (71 aa)
Arcn1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (511 aa)
Hnf1bHepatocyte nuclear factor 1-beta. (593 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
Lhx5LIM/homeobox protein Lhx5. (402 aa)
Slc25a46Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (289 aa)
I79_019287Oligophrenin-1. (371 aa)
Atf5Cyclic AMP-dependent transcription factor ATF-5. (279 aa)
HnrnpdHeterogeneous nuclear ribonucleoprotein D0. (257 aa)
I79_019429Contactin-1. (461 aa)
Sstr1Somatostatin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
I79_019616Seizure protein 6. (1017 aa)
Rbfox2RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (377 aa)
I79_019981Lysine-specific demethylase 2B. (484 aa)
RereArginine-glutamic acid dipeptide repeats protein. (173 aa)
I79_020166Arginine-glutamic acid dipeptide repeats protein. (1473 aa)
I79_020248Gamma-aminobutyric acid receptor subunit beta-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (231 aa)
I79_020650Protein very KIND. (1485 aa)
Agtpbp1Cytosolic carboxypeptidase 1. (1087 aa)
FlnaFilamin-A. (2488 aa)
I79_021503Paired mesoderm homeobox protein 2A. (139 aa)
I79_021938Mothers against decapentaplegic-like 1. (122 aa)
I79_022050Oligophrenin-1. (93 aa)
Fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
I79_022316Kelch-like protein 5. (198 aa)
I79_022486GS homeobox 2. (100 aa)
Gbx2Homeobox protein GBX-2. (222 aa)
I79_022599Fas apoptotic inhibitory molecule 2. (360 aa)
RoraNuclear receptor ROR-alpha. (959 aa)
I79_022712Glutamate [NMDA] receptor subunit zeta-1. (998 aa)
Abl1Tyrosine-protein kinase transforming protein Abl. (322 aa)
I79_023135Polypyrimidine tract-binding protein 2. (141 aa)
Ptbp2Polypyrimidine tract-binding protein 2. (212 aa)
I79_024010Oligophrenin-1. (243 aa)
Hes3Transcription factor HES-3. (201 aa)
I79_024341Paired mesoderm homeobox protein 2B. (182 aa)
Sstr3Somatostatin receptor type 3; Belongs to the G-protein coupled receptor 1 family. (425 aa)
I79_024959Mothers against decapentaplegic-like 1. (161 aa)
I79_025312Kelch-like protein 5. (193 aa)
I79_025316Mothers against decapentaplegic-like 1. (104 aa)
Serpine2Glia-derived nexin; Belongs to the serpin family. (189 aa)
I79_025459Mothers against decapentaplegic-like 1. (117 aa)
I79_025510Kelch-like protein 5. (59 aa)
I79_025513Mothers against decapentaplegic-like 1. (151 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (101 aa)
Egr2Early growth response protein 2. (410 aa)
I79_025783Mothers against decapentaplegic-like 1. (97 aa)
NADH4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (514 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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