STRINGSTRING
Krt17 Krt17 I79_006225 I79_006225 Ctnnb1 Ctnnb1 Ext1 Ext1 Fst Fst Snai1 Snai1 Tmem79 Tmem79 Ngfr Ngfr Dlx3 Dlx3 Intu Intu Runx3 Runx3 Runx1 Runx1 Atp7a Atp7a Gorab Gorab I79_015320 I79_015320 Sostdc1 Sostdc1 Dicer1 Dicer1 Fgf7 Fgf7 Testin-2 Testin-2 Fgfr2 Fgfr2 I79_025440 I79_025440 I79_025833 I79_025833 I79_025901 I79_025901 I79_000092 I79_000092 Tp63 Tp63 Pla2g10 Pla2g10 Smo Smo Gli2 Gli2 Igfbp5 Igfbp5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Krt17Keratin, type I cytoskeletal 17; Belongs to the intermediate filament family. (432 aa)
I79_006225Sonic hedgehog protein. (226 aa)
Ctnnb1Catenin beta-1. (781 aa)
Ext1Exostosin-1. (388 aa)
FstFollistatin. (316 aa)
Snai1Zinc finger protein SNAI1-like protein. (264 aa)
Tmem79Transmembrane protein 79. (395 aa)
NgfrTumor necrosis factor receptor superfamily member 16. (429 aa)
Dlx3Homeobox protein DLX-3. (287 aa)
IntuPDZ domain-containing protein 6. (938 aa)
Runx3Runt-related transcription factor 3. (299 aa)
Runx1Runt-related transcription factor 1. (462 aa)
Atp7aCopper-transporting ATPase 1. (1457 aa)
GorabRAB6-interacting golgin. (367 aa)
I79_015320Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (477 aa)
Sostdc1Sclerostin domain-containing protein 1. (193 aa)
Dicer1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Testin-2Testin-2; Belongs to the peptidase C1 family. (401 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
I79_025440Cathepsin L1; Belongs to the peptidase C1 family. (333 aa)
I79_025833Keratin, type I cytoskeletal 28; Belongs to the intermediate filament family. (268 aa)
I79_025901Keratin, type I cytoskeletal 27; Belongs to the intermediate filament family. (227 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (642 aa)
Pla2g10Phospholipase A(2). (140 aa)
SmoSmoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
Gli2Zinc finger protein GLI2. (1547 aa)
Igfbp5Insulin-like growth factor-binding protein 5. (271 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (16%) [HD]