STRINGSTRING
I79_006113 I79_006113 I79_014258 I79_014258 Pla2g5 Pla2g5 Gper1 Gper1 TARBP2 TARBP2 Pcbp2 Pcbp2 PPARG PPARG I79_015010 I79_015010 I79_015046 I79_015046 Atg5 Atg5 I79_015056 I79_015056 I79_015366 I79_015366 Mettl3 Mettl3 I79_015453 I79_015453 Ttll12 Ttll12 I79_015916 I79_015916 Adora2a Adora2a Adipoq Adipoq I79_016141 I79_016141 Gpatch3 Gpatch3 Fgl2 Fgl2 Nlrc3 Nlrc3 H671_7g18521 H671_7g18521 I79_016800 I79_016800 Clec12b Clec12b Traf3ip1 Traf3ip1 Banf1 Banf1 C1qtnf12 C1qtnf12 I79_018194 I79_018194 Isg15 Isg15 I79_018337 I79_018337 I79_018586 I79_018586 Adcyap1 Adcyap1 Nr1d1 Nr1d1 Npy5r Npy5r Gpr17 Gpr17 Apoa1 Apoa1 Mylk3 Mylk3 Socs5 Socs5 Nlrx1 Nlrx1 I79_020667 I79_020667 I79_020974 I79_020974 I79_021153 I79_021153 I79_021300 I79_021300 I79_021556 I79_021556 I79_021561 I79_021561 Tnfaip6 Tnfaip6 I79_022003 I79_022003 Oas3 Oas3 Alox5 Alox5 I79_022023 I79_022023 Lrfn5 Lrfn5 I79_022390 I79_022390 Ppara Ppara Rora Rora I79_023414 I79_023414 CgPICR_015544 CgPICR_015544 Tkfc Tkfc Rnf26 Rnf26 I79_023695 I79_023695 Ash1l Ash1l Adar Adar Il10 Il10 Itch Itch Otulin Otulin Otulinl Otulinl I79_007462 I79_007462 I79_007339 I79_007339 Mul1 Mul1 I79_007088 I79_007088 I79_006981 I79_006981 Cck Cck Smad3 Smad3 Gpx1 Gpx1 Serpinf1 Serpinf1 Ets1 Ets1 IL2 IL2 Ghsr Ghsr Acp5 Acp5 Gata3 Gata3 Dusp10 Dusp10 Foxf1 Foxf1 I79_000272 I79_000272 Parp14 Parp14 Nt5e Nt5e Tnfrsf1a Tnfrsf1a I79_001429 I79_001429 Mmp12 Mmp12 Ppm1b Ppm1b Tnfaip3 Tnfaip3 Il22ra2 Il22ra2 Lyar Lyar Pla2g10 Pla2g10 I79_002263 I79_002263 I79_002265 I79_002265 I79_002266 I79_002266 Ghrl Ghrl Nploc4 Nploc4 Samhd1 Samhd1 I79_002662 I79_002662 Gps2 Gps2 I79_002785 I79_002785 C1qbp C1qbp Mdk Mdk Nr1h3 Nr1h3 Cnot7 Cnot7 I79_003514 I79_003514 I79_003522 I79_003522 Mfhas1 Mfhas1 Tyro3 Tyro3 Nr1d2 Nr1d2 Arg2 Arg2 Ythdf2 Ythdf2 I79_004199 I79_004199 Isl1 Isl1 Trafd1 Trafd1 Drd2 Drd2 I79_004403 I79_004403 Npy Npy Tnfaip8l2 Tnfaip8l2 Psmb4 Psmb4 Socs3 Socs3 Sec14l1 Sec14l1 Adora1 Adora1 I79_024961 I79_024961 I79_024962 I79_024962 I79_025170 I79_025170 I79_025295 I79_025295 I79_025357 I79_025357 I79_025366 I79_025366 Igf1 Igf1 Cdh5 Cdh5 Tspan6 Tspan6 Nod2 Nod2 I79_005603 I79_005603 Uaca Uaca I79_007986 I79_007986 Dcst1 Dcst1 I79_008148 I79_008148 I79_025482 I79_025482 Nfkb1 Nfkb1 I79_025690 I79_025690 I79_025745 I79_025745 I79_026091 I79_026091 LDLR LDLR Nlrp6 Nlrp6 Trim21 Trim21 Usp18 Usp18 I79_012974 I79_012974 Macir Macir Ier3 Ier3 I79_013172 I79_013172 Tap1 Tap1 Rb1 Rb1 Git1 Git1 Serping1 Serping1 I79_013440 I79_013440 Stat2 Stat2 Ppard Ppard Ilrun Ilrun Dnaja3 Dnaja3 Psma1 Psma1 Cactin Cactin Nmi Nmi I79_024593 I79_024593 Tnfrsf1b Tnfrsf1b Riok3 Riok3 Ythdf3 Ythdf3 I79_012868 I79_012868 Hgf Hgf Apoe Apoe Pbk Pbk Foxp3 Foxp3 Bcr Bcr Dhx58 Dhx58 Ada Ada Grn Grn Trex1 Trex1 I79_011219 I79_011219 C1qtnf3 C1qtnf3 Gpr31 Gpr31 Zfp36 Zfp36 Sirt2 Sirt2 Cx3cl1 Cx3cl1 I79_010477 I79_010477 Mvk Mvk Acod1 Acod1 I79_010073 I79_010073 Syt11 Syt11 Ptgis Ptgis Cd276 Cd276 IL12B IL12B I79_008716 I79_008716 I79_008518 I79_008518 Crk Crk Abr Abr
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_006113Poly(RC)-binding protein 2. (306 aa)
I79_014258Cysteine dioxygenase. (99 aa)
Pla2g5Phospholipase A(2). (137 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
TARBP2RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (365 aa)
Pcbp2Poly(RC)-binding protein 2. (362 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
I79_015010Putative E3 ubiquitin-protein ligase makorin-2. (377 aa)
I79_015046Low-density lipoprotein receptor. (160 aa)
Atg5Autophagy protein 5; Involved in autophagic vesicle formation. (147 aa)
I79_015056Neuronal acetylcholine receptor subunit alpha-7. (412 aa)
I79_015366Sharpin. (377 aa)
Mettl3N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa)
I79_015453C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
Ttll12Tubulin--tyrosine ligase-like protein 12. (655 aa)
I79_015916Insulin-like growth factor II. (155 aa)
Adora2aAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (408 aa)
AdipoqAdiponectin. (248 aa)
I79_016141Serine protease inhibitor Kazal-type 5. (832 aa)
Gpatch3G patch domain-containing protein 3. (336 aa)
Fgl2Fibroleukin. (613 aa)
Nlrc3Protein NLRC3. (975 aa)
H671_7g18521Pyrin-like protein. (685 aa)
I79_016800Cytochrome P450 19A1; Belongs to the cytochrome P450 family. (436 aa)
Clec12bC-type lectin domain family 12 member B. (177 aa)
Traf3ip1TRAF3-interacting protein 1. (88 aa)
Banf1Barrier-to-autointegration factor. (89 aa)
C1qtnf12Protein FAM132A. (61 aa)
I79_018194Protein FAM132A. (127 aa)
Isg15Ubiquitin-like protein ISG15-like protein. (156 aa)
I79_018337RING finger protein 26. (76 aa)
I79_018586Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
Adcyap1Pituitary adenylate cyclase-activating polypeptide-like protein. (176 aa)
Nr1d1Nuclear receptor subfamily 1 group D member 1. (508 aa)
Npy5rNeuropeptide Y receptor type 5-like protein. (466 aa)
Gpr17Uracil nucleotide/cysteinyl leukotriene receptor; Belongs to the G-protein coupled receptor 1 family. (339 aa)
Apoa1Apolipoprotein A-I. (264 aa)
Mylk3Vacuolar protein sorting-associated protein 35. (1427 aa)
Socs5Suppressor of cytokine signaling 5. (530 aa)
Nlrx1NLR family member X1. (2478 aa)
I79_020667Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (256 aa)
I79_020974Serine protease HTRA1. (268 aa)
I79_021153Putative ATP-dependent RNA helicase DHX58. (89 aa)
I79_021300Poly [ADP-ribose] polymerase. (324 aa)
I79_021556C-type lectin domain family 2 member D11. (210 aa)
I79_021561C-type lectin domain family 2 member D11. (262 aa)
Tnfaip6Tumor necrosis factor-inducible gene 6 protein. (275 aa)
I79_0220032'-5'-oligoadenylate synthetase 3. (365 aa)
Oas32'-5'-oligoadenylate synthetase 3. (685 aa)
Alox5Arachidonate 5-lipoxygenase. (674 aa)
I79_022023Arginase-1; Belongs to the arginase family. (281 aa)
Lrfn5Leucine-rich repeat and fibronectin type-III domain-containing protein 5. (770 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
RoraNuclear receptor ROR-alpha. (959 aa)
I79_023414Poly(RC)-binding protein 2. (176 aa)
CgPICR_015544Poly(RC)-binding protein 2. (73 aa)
TkfcBifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (Cyclizing). (578 aa)
Rnf26RING finger protein 26. (427 aa)
I79_023695Malignant fibrous histiocytoma-amplified sequence 1-like. (200 aa)
Ash1lPutative histone-lysine N-methyltransferase ASH1L. (1546 aa)
AdarDouble-stranded RNA-specific adenosine deaminase. (1174 aa)
Il10Interleukin-10. (178 aa)
ItchE3 ubiquitin-protein ligase. (851 aa)
OtulinProtein FAM105B. (298 aa)
OtulinlProtein FAM105A. (344 aa)
I79_007462Poly [ADP-ribose] polymerase 14. (125 aa)
I79_007339Protein NOV-like. (256 aa)
Mul1Mitochondrial ubiquitin ligase activator of NFKB 1. (321 aa)
I79_007088Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (870 aa)
I79_006981G-protein coupled receptor 120. (318 aa)
CckCholecystokinin. (115 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
Gpx1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
Serpinf1Pigment epithelium-derived factor; Belongs to the serpin family. (94 aa)
Ets1Protein C-ets-1. (257 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Acp5Tartrate-resistant acid phosphatase type 5. (330 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
Dusp10Dual specificity protein phosphatase 10. (482 aa)
Foxf1Forkhead box protein F1. (320 aa)
I79_000272WAP four-disulfide core domain protein 1. (275 aa)
Parp14Poly [ADP-ribose] polymerase. (1786 aa)
Nt5e5'-nucleotidase; Belongs to the 5'-nucleotidase family. (556 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (355 aa)
I79_001429Lysophospholipid acyltransferase 5; Belongs to the membrane-bound acyltransferase family. (500 aa)
Mmp12Macrophage metalloelastase. (464 aa)
Ppm1bProtein phosphatase 1B. (479 aa)
Tnfaip3Tumor necrosis factor, alpha-induced protein 3. (776 aa)
Il22ra2Interleukin-22 receptor subunit alpha-2. (239 aa)
LyarCell growth-regulating nucleolar protein. (382 aa)
Pla2g10Phospholipase A(2). (140 aa)
I79_002263Serpin B9; Belongs to the serpin family. (339 aa)
I79_002265Serpin B9; Belongs to the serpin family. (375 aa)
I79_002266Serpin B9; Belongs to the serpin family. (262 aa)
GhrlAppetite-regulating hormone. (100 aa)
Nploc4Nuclear protein localization protein 4-like. (217 aa)
Samhd1SAM domain and HD domain-containing protein 1. (670 aa)
I79_002662Interleukin-1 receptor-associated kinase 3. (537 aa)
Gps2G protein pathway suppressor 2. (327 aa)
I79_002785Beta-arrestin-2. (65 aa)
C1qbpComplement component 1 Q subcomponent-binding protein, mitochondrial. (209 aa)
MdkMidkine. (160 aa)
Nr1h3Oxysterols receptor LXR-alpha. (402 aa)
Cnot7CCR4-NOT transcription complex subunit 7-like isoform 1. (285 aa)
I79_003514T-cell surface protein tactile. (353 aa)
I79_003522OX-2 membrane glycoprotein. (268 aa)
Mfhas1Malignant fibrous histiocytoma-amplified sequence 1-like. (1025 aa)
Tyro3Tyrosine-protein kinase receptor TYRO3. (816 aa)
Nr1d2Nuclear receptor subfamily 1 group D member 2. (265 aa)
Arg2Arginase. (305 aa)
Ythdf2YTH domain family protein 2. (529 aa)
I79_004199Acid sphingomyelinase-like phosphodiesterase 3b. (392 aa)
Isl1Insulin gene enhancer protein ISL-1. (257 aa)
Trafd1TRAF-type zinc finger domain-containing protein 1. (570 aa)
Drd2D(2) dopamine receptor. (274 aa)
I79_004403D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
NpyNeuropeptide Y. (148 aa)
Tnfaip8l2Tumor necrosis factor, alpha-induced protein 8-like protein 2. (184 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Socs3Suppressor of cytokine signaling 3. (225 aa)
Sec14l1SEC14-like protein 1. (716 aa)
Adora1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
I79_024961Uncharacterized protein C19orf29-like. (328 aa)
I79_024962Uncharacterized protein C19orf29-like. (171 aa)
I79_025170Slit-like 2 protein. (345 aa)
I79_025295NACHT, LRR and PYD domains-containing protein 12. (91 aa)
I79_025357Hereditary hemochromatosis protein-like; Belongs to the MHC class I family. (326 aa)
I79_025366Hereditary hemochromatosis protein-like; Belongs to the MHC class I family. (282 aa)
Igf1Insulin-like growth factor I. (75 aa)
Cdh5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (763 aa)
Tspan6Tetraspanin. (245 aa)
Nod2Nucleotide-binding oligomerization domain-containing protein 2. (989 aa)
I79_005603Putative ubiquitin carboxyl-terminal hydrolase CYLD. (730 aa)
UacaUveal autoantigen with coiled-coil domains and ankyrin repeats. (1396 aa)
I79_007986Putative histone-lysine N-methyltransferase ASH1L. (455 aa)
Dcst1DC-STAMP domain-containing protein 1. (642 aa)
I79_008148Glutathione peroxidase 2. (151 aa)
I79_025482Nuclear factor NF-kappa-B p105 subunit. (144 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (509 aa)
I79_025690Malignant fibrous histiocytoma-amplified sequence 1. (391 aa)
I79_025745Nuclear receptor subfamily 1 group D member 1. (226 aa)
I79_026091Pigment epithelium-derived factor; Belongs to the serpin family. (58 aa)
LDLRLow-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family. (862 aa)
Nlrp6NACHT, LRR and PYD domains-containing protein 6. (995 aa)
Trim2152 kDa Ro protein. (463 aa)
Usp18Ubl carboxyl-terminal hydrolase 18. (60 aa)
I79_012974Putative ubiquitin carboxyl-terminal hydrolase 41. (87 aa)
MacirUPF0684 protein C5orf30-like. (207 aa)
Ier3Radiation-inducible immediate-early gene IEX-1. (160 aa)
I79_013172H-2 class I histocompatibility antigen, L-D alpha chain; Belongs to the MHC class I family. (209 aa)
Tap1Antigen peptide transporter 1. (725 aa)
Rb1Retinoblastoma-associated protein. (302 aa)
Git1ARF GTPase-activating protein GIT1. (809 aa)
Serping1Plasma protease C1 inhibitor; Belongs to the serpin family. (177 aa)
I79_013440Calcitonin gene-related peptide type 1 receptor. (426 aa)
Stat2Signal transducer and activator of transcription. (806 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
IlrunUncharacterized protein C6orf106. (217 aa)
Dnaja3DnaJ-like subfamily A member 3, mitochondrial. (453 aa)
Psma1Proteasome subunit alpha type. (263 aa)
CactinUncharacterized protein C19orf29-like. (425 aa)
NmiN-myc-interactor. (303 aa)
I79_024593Uncharacterized protein. (194 aa)
Tnfrsf1bTumor necrosis factor receptor superfamily member 1B. (477 aa)
Riok3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa)
Ythdf3YTH domain family protein 3. (588 aa)
I79_012868Acyloxyacyl hydrolase. (185 aa)
HgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
ApoeApolipoprotein E. (313 aa)
PbkLymphokine-activated killer T-cell-originated protein kinase. (323 aa)
Foxp3Forkhead box protein P3. (428 aa)
BcrBreakpoint cluster region protein. (1193 aa)
Dhx58Putative ATP-dependent RNA helicase DHX58. (56 aa)
AdaAdenosine deaminase. (363 aa)
GrnGranulins. (592 aa)
Trex1Three prime repair exonuclease 1. (320 aa)
I79_011219Vitamin K-dependent protein C. (381 aa)
C1qtnf3Complement C1q tumor necrosis factor-related protein 3. (319 aa)
Gpr31Putative G-protein coupled receptor 31; Belongs to the G-protein coupled receptor 1 family. (319 aa)
Zfp36Tristetraproline. (315 aa)
Sirt2NAD-dependent deacetylase sirtuin-2. (83 aa)
Cx3cl1Fractalkine. (335 aa)
I79_010477Protein NLRC5. (1513 aa)
MvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (389 aa)
Acod1Immune-responsive gene 1 protein. (290 aa)
I79_010073Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (511 aa)
Syt11Synaptotagmin-11. (111 aa)
PtgisProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (501 aa)
Cd276CD276 antigen. (316 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
I79_008716Tripartite motif-containing protein 38. (304 aa)
I79_008518Poly(RC)-binding protein 2. (176 aa)
CrkProto-oncogene C-crk. (327 aa)
AbrActive breakpoint cluster region-related protein. (769 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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