(7 nodes) Positive regulation of fever generation network (Cricetulus griseus)

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Your Input:
	Tnfsf11	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (199 aa)
	I79_015458	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (337 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
	Ccl5	C-C motif chemokine. (91 aa)
	I79_000677	Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (415 aa)
	Ptgs2	Prostaglandin G/H synthase 2. (604 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ccl5	I79_015458	G3I8B1	G3HWU5	C-C motif chemokine.	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.993
Ccl5	IL1B	G3I8B1	G3I1B0	C-C motif chemokine.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.770
Ccl5	Ptgs2	G3I8B1	G3GWV6	C-C motif chemokine.	Prostaglandin G/H synthase 2.	0.500
Ccl5	Tnf	G3I8B1	G3HZG9	C-C motif chemokine.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.759
I79_015458	Ccl5	G3HWU5	G3I8B1	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.993
I79_015458	IL1B	G3HWU5	G3I1B0	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.438
I79_015458	Tnf	G3HWU5	G3HZG9	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.527
IL1B	Ccl5	G3I1B0	G3I8B1	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	C-C motif chemokine.	0.770
IL1B	I79_015458	G3I1B0	G3HWU5	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.438
IL1B	Ptgs2	G3I1B0	G3GWV6	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Prostaglandin G/H synthase 2.	0.829
IL1B	Tnf	G3I1B0	G3HZG9	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.914
IL1B	Tnfsf11	G3I1B0	G3HGS7	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.	0.555
Ptgs2	Ccl5	G3GWV6	G3I8B1	Prostaglandin G/H synthase 2.	C-C motif chemokine.	0.500
Ptgs2	IL1B	G3GWV6	G3I1B0	Prostaglandin G/H synthase 2.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.829
Ptgs2	Tnf	G3GWV6	G3HZG9	Prostaglandin G/H synthase 2.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.591
Tnf	Ccl5	G3HZG9	G3I8B1	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	C-C motif chemokine.	0.759
Tnf	I79_015458	G3HZG9	G3HWU5	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.527
Tnf	IL1B	G3HZG9	G3I1B0	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.914
Tnf	Ptgs2	G3HZG9	G3GWV6	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Prostaglandin G/H synthase 2.	0.591
Tnf	Tnfsf11	G3HZG9	G3HGS7	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.	0.585