(6 nodes) Insulin-like growth factor II binding network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Igfbp2	Insulin-like growth factor-binding protein 2. (177 aa)
	Igfbp5	Insulin-like growth factor-binding protein 5. (271 aa)
	Igf2r	Cation-independent mannose-6-phosphate receptor. (1700 aa)
	Igfbp1	Insulin-like growth factor-binding protein 1. (272 aa)
	Insr	Insulin receptor. (114 aa)
	Igfbp4	Insulin-like growth factor-binding protein 4. (254 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Igf2r	Igfbp1	G3HGQ1	G3HL64	Cation-independent mannose-6-phosphate receptor.	Insulin-like growth factor-binding protein 1.	0.486
Igf2r	Igfbp2	G3HGQ1	G3H3Z6	Cation-independent mannose-6-phosphate receptor.	Insulin-like growth factor-binding protein 2.	0.472
Igf2r	Insr	G3HGQ1	G3HWV6	Cation-independent mannose-6-phosphate receptor.	Insulin receptor.	0.430
Igfbp1	Igf2r	G3HL64	G3HGQ1	Insulin-like growth factor-binding protein 1.	Cation-independent mannose-6-phosphate receptor.	0.486
Igfbp1	Igfbp4	G3HL64	G3I5N6	Insulin-like growth factor-binding protein 1.	Insulin-like growth factor-binding protein 4.	0.890
Igfbp2	Igf2r	G3H3Z6	G3HGQ1	Insulin-like growth factor-binding protein 2.	Cation-independent mannose-6-phosphate receptor.	0.472
Igfbp2	Igfbp4	G3H3Z6	G3I5N6	Insulin-like growth factor-binding protein 2.	Insulin-like growth factor-binding protein 4.	0.542
Igfbp4	Igfbp1	G3I5N6	G3HL64	Insulin-like growth factor-binding protein 4.	Insulin-like growth factor-binding protein 1.	0.890
Igfbp4	Igfbp2	G3I5N6	G3H3Z6	Insulin-like growth factor-binding protein 4.	Insulin-like growth factor-binding protein 2.	0.542
Igfbp4	Igfbp5	G3I5N6	G3H3Z7	Insulin-like growth factor-binding protein 4.	Insulin-like growth factor-binding protein 5.	0.513
Igfbp5	Igfbp4	G3H3Z7	G3I5N6	Insulin-like growth factor-binding protein 5.	Insulin-like growth factor-binding protein 4.	0.513
Insr	Igf2r	G3HWV6	G3HGQ1	Insulin receptor.	Cation-independent mannose-6-phosphate receptor.	0.430