STRINGSTRING
I79_025694 I79_025694 Map1lc3b Map1lc3b Usp9x Usp9x Dtx3l Dtx3l Tiam1 Tiam1 Vtn Vtn Wnt5a Wnt5a Plk2 Plk2 Fam220a Fam220a Lfng Lfng Usp33 Usp33 Rfng Rfng Krit1 Krit1 I79_002522 I79_002522 Mapre3 Mapre3 Actr3 Actr3 Nphp3 Nphp3 Blk Blk Aktip Aktip B2m B2m I79_004172 I79_004172 I79_004332 I79_004332 I79_004339 I79_004339 Ide Ide Epb41l5 Epb41l5 Tert Tert I79_025846 I79_025846 I79_005532 I79_005532 Ppp2cb Ppp2cb I79_005909 I79_005909 I79_005999 I79_005999 I79_006254 I79_006254 I79_006517 I79_006517 Mmp9 Mmp9 Cav1 Cav1 Gsk3b Gsk3b I79_007632 I79_007632 Cdk5 Cdk5 Pkd1 Pkd1 Ticam1 Ticam1 Hfe Hfe Mapre1 Mapre1 Cldn5 Cldn5 I79_010016 I79_010016 I79_010136 I79_010136 Sppl3 Sppl3 Amfr Amfr Ngf Ngf I79_010839 I79_010839 Stk3 Stk3 I79_011392 I79_011392 I79_011406 I79_011406 Stk4 Stk4 App App Rapgef2 Rapgef2 Rpl11 Rpl11 Psen1 Psen1 CgPICR_014495 CgPICR_014495 Ripk2 Ripk2 Apoe Apoe Caprin2 Caprin2 I79_012685 I79_012685 I79_012686 I79_012686 Flot1 Flot1 Spon1 Spon1 I79_013781 I79_013781 I79_013782 I79_013782 Bambi Bambi I79_014483 I79_014483 Sting1 Sting1 Plxnd1 Plxnd1 Abl2 Abl2 Lrp1 Lrp1 I79_015356 I79_015356 I79_015679 I79_015679 I79_015695 I79_015695 Ppp2ca Ppp2ca I79_016879 I79_016879 Nvl Nvl Arhgef7 Arhgef7 Ramp1 Ramp1 I79_017593 I79_017593 Agrn Agrn Ep300 Ep300 Add2 Add2 Men1 Men1 I79_019318 I79_019318 Trib3 Trib3 I79_020783 I79_020783 Hip1r Hip1r Tspan5 Tspan5 I79_021577 I79_021577 I79_021835 I79_021835 I79_021836 I79_021836 I79_021837 I79_021837 Anxa2 Anxa2 Abl1 Abl1 I79_022994 I79_022994 H671_2g5922 H671_2g5922 Tcf7l2 Tcf7l2 Arrb1 Arrb1 Mfng Mfng I79_024397 I79_024397 I79_024415 I79_024415 Trim21 Trim21 I79_025158 I79_025158 I79_025376 I79_025376 I79_025454 I79_025454 I79_025798 I79_025798 Csf3 Csf3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_025694Derlin-1. (87 aa)
Map1lc3bMicrotubule-associated proteins 1A/1B light chain 3B. (125 aa)
Usp9xPutative ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2558 aa)
Dtx3lProtein deltex-3-like. (763 aa)
Tiam1T-lymphoma invasion and metastasis-inducing protein 1. (1591 aa)
VtnVitronectin. (876 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Plk2Serine/threonine-protein kinase PLK. (682 aa)
Fam220aSTAT3-interacting protein as a repressor. (226 aa)
LfngBeta-1,3-N-acetylglucosaminyltransferase. (378 aa)
Usp33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (910 aa)
RfngBeta-1,3-N-acetylglucosaminyltransferase radical fringe. (229 aa)
Krit1Krev interaction trapped protein 1. (740 aa)
I79_002522GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (227 aa)
Mapre3Microtubule-associated protein RP/EB family member 3. (281 aa)
Actr3Actin-related protein 3; Belongs to the actin family. (418 aa)
Nphp3Nephrocystin-3. (542 aa)
BlkTyrosine-protein kinase. (500 aa)
AktipAKT-interacting protein. (213 aa)
B2mBeta-2-microglobulin. (54 aa)
I79_004172Protein 4.1. (773 aa)
I79_004332Heat shock 70 kDa protein 4. (559 aa)
I79_004339Serine/threonine-protein phosphatase. (244 aa)
IdeInsulin-degrading enzyme; Belongs to the peptidase M16 family. (978 aa)
Epb41l5Band 4.1-like protein 5. (717 aa)
TertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (138 aa)
I79_025846Derlin-1. (54 aa)
I79_005532Ras-related protein Ral-B. (227 aa)
Ppp2cbSerine/threonine-protein phosphatase. (356 aa)
I79_005909Peptidyl-prolyl cis-trans isomerase. (242 aa)
I79_005999Spectrin alpha chain, erythrocyte. (326 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006517Spectrin alpha chain, erythrocyte. (181 aa)
Mmp9Matrix metalloproteinase-9. (710 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Gsk3bGlycogen synthase kinase-3 beta. (328 aa)
I79_00763260S ribosomal protein L11. (93 aa)
Cdk5Cell division protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
Pkd1Polycystin-1. (3717 aa)
Ticam1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (699 aa)
HfeHereditary hemochromatosis protein-like; Belongs to the MHC class I family. (306 aa)
Mapre1Microtubule-associated protein RP/EB family member 1-like protein. (268 aa)
Cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (238 aa)
I79_01001660S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (365 aa)
I79_010136Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (230 aa)
Sppl3Signal peptide peptidase-like 3. (347 aa)
AmfrAutocrine motility factor receptor. (464 aa)
NgfBeta-nerve growth factor; Belongs to the NGF-beta family. (112 aa)
I79_010839Eukaryotic translation initiation factor 2-alpha kinase 3. (783 aa)
Stk3Serine/threonine-protein kinase 3. (260 aa)
I79_011392Phosphoinositide phospholipase C. (867 aa)
I79_011406Ephrin type-B receptor 6. (983 aa)
Stk4Serine/threonine-protein kinase 4. (487 aa)
AppAmyloid beta A4 protein. (433 aa)
Rapgef2Uncharacterized protein. (524 aa)
Rpl1160S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (178 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
CgPICR_014495GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
Ripk2Receptor-interacting serine/threonine-protein kinase 2. (402 aa)
ApoeApolipoprotein E. (313 aa)
Caprin2Caprin-2. (364 aa)
I79_012685Caprin-2. (215 aa)
I79_012686Caprin-2. (132 aa)
Flot1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (418 aa)
Spon1Spondin-1. (51 aa)
I79_013781Spondin-1. (61 aa)
I79_013782Spondin-1. (178 aa)
BambiBMP and activin membrane-bound inhibitor-like. (218 aa)
I79_014483Serine/threonine-protein kinase 3. (118 aa)
Sting1Transmembrane protein 173. (315 aa)
Plxnd1Plexin-D1. (612 aa)
Abl2Tyrosine-protein kinase. (1167 aa)
Lrp1Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
I79_015356Heat shock factor protein 1. (524 aa)
I79_01567960S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (198 aa)
I79_015695Microtubule-associated proteins 1A/1B light chain 3B. (257 aa)
Ppp2caSerine/threonine-protein phosphatase. (303 aa)
I79_016879Alpha-adducin. (735 aa)
NvlNuclear valosin-containing protein-like; Belongs to the AAA ATPase family. (311 aa)
Arhgef7Rho guanine nucleotide exchange factor 7. (646 aa)
Ramp1Receptor activity-modifying protein 1. (126 aa)
I79_017593Phosphofurin acidic cluster sorting protein 1. (703 aa)
AgrnAgrin. (2036 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
Add2Beta-adducin. (725 aa)
Men1Menin. (610 aa)
I79_019318Microtubule-associated proteins 1A/1B light chain 3B. (71 aa)
Trib3Tribbles-like 3. (353 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
Hip1rHuntingtin-interacting protein 1-related protein. (505 aa)
Tspan5Tetraspanin. (872 aa)
I79_021577Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (248 aa)
I79_021835Leucine-rich repeat serine/threonine-protein kinase 2. (354 aa)
I79_021836Leucine-rich repeat serine/threonine-protein kinase 2. (1184 aa)
I79_021837Leucine-rich repeat serine/threonine-protein kinase 2. (441 aa)
Anxa2Annexin. (244 aa)
Abl1Tyrosine-protein kinase transforming protein Abl. (322 aa)
I79_022994Dapper-like 1. (530 aa)
H671_2g5922GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
Arrb1Beta-arrestin-1. (422 aa)
MfngBeta-1,3-N-acetylglucosaminyltransferase manic fringe. (324 aa)
I79_024397GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (128 aa)
I79_024415Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (755 aa)
Trim2152 kDa Ro protein. (463 aa)
I79_025158Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform. (65 aa)
I79_02537660S ribosomal protein L11. (97 aa)
I79_025454Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (182 aa)
I79_025798Vitronectin. (230 aa)
Csf3Granulocyte colony-stimulating factor. (208 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (12%) [HD]