(91 nodes) Positive regulation of lipid transport network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
	CgPICR_014663	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase-like protein; Belongs to the cytochrome P450 family. (501 aa)
	Pltp	Phospholipid transfer protein. (493 aa)
	I79_006708	Secretory phospholipase A2 receptor. (593 aa)
	I79_006547	Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (311 aa)
	Lrat	Lecithin retinol acyltransferase-like protein. (227 aa)
	Dbi	Acyl-CoA-binding protein. (119 aa)
	I79_004757	Complement C1q tumor necrosis factor-related protein 1. (314 aa)
	I79_004285	p2X purinoceptor 7. (805 aa)
	Fabp3	Fatty acid-binding protein, heart; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (121 aa)
	Prelid1	PRELI domain-containing protein 1, mitochondrial. (156 aa)
	Edn1	Endothelin-1. (202 aa)
	H671_5g14837	Tumor necrosis factor ligand superfamily member 6-like isoform 1; Belongs to the tumor necrosis factor family. (192 aa)
	Nr1h3	Oxysterols receptor LXR-alpha. (402 aa)
	Gps2	G protein pathway suppressor 2. (327 aa)
	Bmp6	Bone morphogenetic protein 6. (296 aa)
	Pla2g4a	Phospholipase A2. (749 aa)
	Pla2g10	Phospholipase A(2). (140 aa)
	Scp2	Non-specific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
	Scp2d1	Uncharacterized protein C20orf79-like. (156 aa)
	Prkcd	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (437 aa)
	I79_001429	Lysophospholipid acyltransferase 5; Belongs to the membrane-bound acyltransferase family. (500 aa)
	Abca1	ATP-binding cassette sub-family A member 1. (2261 aa)
	Tmf1	TATA element modulatory factor. (1094 aa)
	C1qtnf6	Complement C1q tumor necrosis factor-related protein 6. (266 aa)
	P2ry2	p2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (151 aa)
	I79_024789	Putative phospholipid-transporting ATPase IA. (163 aa)
	H671_2g7682	PRELI domain-containing protein 1, mitochondrial. (93 aa)
	Spp1	Osteopontin. (117 aa)
	Pla2g6	85 kDa calcium-independent phospholipase A2. (77 aa)
	Ptch1	Protein patched-like 1. (1114 aa)
	Mfn2	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
	Ptges	Prostaglandin E synthase. (150 aa)
	Anxa2	Annexin. (244 aa)
	Atp8a1	Putative phospholipid-transporting ATPase IA. (121 aa)
	I79_022367	Nucleobindin-2. (420 aa)
	Prap1	Proline-rich acidic protein 1. (148 aa)
	I79_020438	ATP-binding cassette sub-family A member 13. (1347 aa)
	I79_020156	ATP-binding cassette sub-family A member 13. (589 aa)
	I79_020155	ATP-binding cassette sub-family A member 13. (655 aa)
	Acsl1	Long-chain-fatty-acid--CoA ligase 1. (724 aa)
	I79_019630	Liver carboxylesterase 1; Belongs to the type-B carboxylesterase/lipase family. (765 aa)
	I79_019629	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (564 aa)
	I79_019626	Liver carboxylesterase 4. (105 aa)
	I79_019625	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (514 aa)
	Apoa1	Apolipoprotein A-I. (264 aa)
	Nr1h2	Oxysterols receptor LXR-beta. (445 aa)
	Triap1	TP53-regulated inhibitor of apoptosis 1. (79 aa)
	Galr1	Galanin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (351 aa)
	I79_018763	Liver carboxylesterase 4. (393 aa)
	I79_018762	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (370 aa)
	I79_018761	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (448 aa)
	I79_018655	Galanin. (198 aa)
	Nfkbia	NF-kappa-B inhibitor alpha. (224 aa)
	Sstr4	Somatostatin receptor type 4; Belongs to the G-protein coupled receptor 1 family. (384 aa)
	Abca3	ATP-binding cassette sub-family A member 3. (1704 aa)
	Erfe	Protein FAM132B. (344 aa)
	Pla2g3	Group 3 secretory phospholipase A2. (398 aa)
	I79_017374	ATP-binding cassette sub-family A member 12. (506 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
	I79_016800	Cytochrome P450 19A1; Belongs to the cytochrome P450 family. (436 aa)
	Washc1	WAS protein family-like 1. (497 aa)
	Adipoq	Adiponectin. (248 aa)
	I79_015806	Acyl-CoA-binding protein. (87 aa)
	Lrp1	Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
	I79_015031	ATP-binding cassette sub-family A member 12. (892 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
	CgPICR_002342	Acyl-CoA-binding protein. (87 aa)
	Eepd1	Endonuclease/exonuclease/phosphatase family domain-containing protein 1. (569 aa)
	Enpp7	Ectonucleotide pyrophosphatase/phosphodiesterase family member 7. (809 aa)
	Pon1	Serum paraoxonase/arylesterase 1. (355 aa)
	I79_013606	Multidrug resistance protein 3. (1022 aa)
	Lipg	Endothelial lipase. (543 aa)
	I79_012679	DENN domain-containing protein 5B. (1069 aa)
	Apoe	Apolipoprotein E. (313 aa)
	Mapk9	Mitogen-activated protein kinase 9. (303 aa)
	Runx1	Runt-related transcription factor 1. (462 aa)
	I79_012422	Long-chain-fatty-acid--CoA ligase 5. (171 aa)
	Abcg1	ATP-binding cassette sub-family G member 1. (647 aa)
	I79_010458	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (451 aa)
	Tmem30a	Cell cycle control protein; Belongs to the CDC50/LEM3 family. (363 aa)
	Ntsr1	Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
	I79_009834	Disabled-like 2. (705 aa)
	Tnfsf11	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (199 aa)
	Abca7	ATP-binding cassette sub-family A member 7. (408 aa)
	Zdhhc8	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (742 aa)
	Commd1	COMM domain-containing protein 1. (188 aa)
	I79_008640	NF-kappa-B inhibitor alpha. (90 aa)
	I79_008639	NF-kappa-B inhibitor alpha. (52 aa)
	Ghrl	Appetite-regulating hormone. (100 aa)
	Sirt1	NAD-dependent deacetylase sirtuin-1. (554 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abca1	Abcg1	G3GTZ6	G3HLD6	ATP-binding cassette sub-family A member 1.	ATP-binding cassette sub-family G member 1.	0.500
Abca1	Apoa1	G3GTZ6	G3I7Q1	ATP-binding cassette sub-family A member 1.	Apolipoprotein A-I.	0.945
Abca1	Apoe	G3GTZ6	G3HPC9	ATP-binding cassette sub-family A member 1.	Apolipoprotein E.	0.882
Abca1	Cav1	G3GTZ6	G3H9I8	ATP-binding cassette sub-family A member 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.649
Abca1	CgPICR_014663	G3GTZ6	G3H978	ATP-binding cassette sub-family A member 1.	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase-like protein; Belongs to the cytochrome P450 family.	0.456
Abca1	Lipg	G3GTZ6	G3HQJ0	ATP-binding cassette sub-family A member 1.	Endothelial lipase.	0.468
Abca1	Nr1h2	G3GTZ6	G3I731	ATP-binding cassette sub-family A member 1.	Oxysterols receptor LXR-beta.	0.863
Abca1	Nr1h3	G3GTZ6	G3GYK3	ATP-binding cassette sub-family A member 1.	Oxysterols receptor LXR-alpha.	0.891
Abca1	PPARG	G3GTZ6	G3HVG0	ATP-binding cassette sub-family A member 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.693
Abca1	Pltp	G3GTZ6	G3H8V4	ATP-binding cassette sub-family A member 1.	Phospholipid transfer protein.	0.722
Abca1	Pon1	G3GTZ6	G3HT85	ATP-binding cassette sub-family A member 1.	Serum paraoxonase/arylesterase 1.	0.429
Abca1	Zdhhc8	G3GTZ6	G3HEQ5	ATP-binding cassette sub-family A member 1.	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	0.498
Abca7	Apoe	G3HF57	G3HPC9	ATP-binding cassette sub-family A member 7.	Apolipoprotein E.	0.414
Abca7	I79_017374	G3HF57	G3I1V5	ATP-binding cassette sub-family A member 7.	ATP-binding cassette sub-family A member 12.	0.692
Abcg1	Abca1	G3HLD6	G3GTZ6	ATP-binding cassette sub-family G member 1.	ATP-binding cassette sub-family A member 1.	0.500
Abcg1	Apoe	G3HLD6	G3HPC9	ATP-binding cassette sub-family G member 1.	Apolipoprotein E.	0.816
Abcg1	Lipg	G3HLD6	G3HQJ0	ATP-binding cassette sub-family G member 1.	Endothelial lipase.	0.421
Abcg1	Nr1h2	G3HLD6	G3I731	ATP-binding cassette sub-family G member 1.	Oxysterols receptor LXR-beta.	0.632
Abcg1	Nr1h3	G3HLD6	G3GYK3	ATP-binding cassette sub-family G member 1.	Oxysterols receptor LXR-alpha.	0.702
Abcg1	PPARG	G3HLD6	G3HVG0	ATP-binding cassette sub-family G member 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.574