(81 nodes) Integral component of mitochondrial membrane network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_000147	Uncharacterized protein. (54 aa)
	Apool	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (265 aa)
	I79_022349	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (109 aa)
	Bnip3	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (151 aa)
	I79_024644	Mitochondrial inner membrane protein OXA1L. (63 aa)
	Tomm20l	TOMM20-like protein 1. (88 aa)
	Cpt1a	Carnitine O-palmitoyltransferase 1, liver isoform. (127 aa)
	Bak1	Bcl-2-likeous antagonist/killer. (209 aa)
	cytb	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (380 aa)
	Sfxn3	Sidoreflexin. (321 aa)
	Armcx3	Armadillo repeat-containing X-linked protein 3. (379 aa)
	CgPICR_018930	Mitochondrial inner membrane protein COX18. (331 aa)
	Coq2	Para-hydroxybenzoate--polyprenyltransferase, mitochondrial. (103 aa)
	Slc25a4	ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (272 aa)
	I79_019886	Uncharacterized protein. (117 aa)
	Sfxn2	Sidoreflexin. (322 aa)
	Slc8b1	Sodium/potassium/calcium exchanger 6; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (482 aa)
	I79_018654	Carnitine O-palmitoyltransferase 1, liver isoform. (467 aa)
	Dnajc11	DnaJ-like subfamily C member 11. (521 aa)
	I79_017762	Protein SCO2-like, mitochondrial. (259 aa)
	Slc25a3	Phosphate carrier protein, mitochondrial; Belongs to the mitochondrial carrier (TC 2.A.29) family. (231 aa)
	I79_017181	Zinc finger protein 639; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (787 aa)
	Smdt1	UPF0466 protein C22orf32-like, mitochondrial. (107 aa)
	CgPICR_009389	Putative UPF0723 protein C11orf83 like protein. (91 aa)
	Vpreb3	Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial. (222 aa)
	CgPICR_016495	PET100. (76 aa)
	Abcb6	ATP-binding cassette sub-family B member 6, mitochondrial. (228 aa)
	Fundc1	FUN14 domain-containing protein 1. (133 aa)
	Fundc2	FUN14 domain-containing protein 2. (151 aa)
	Micos10	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (76 aa)
	Ppox	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (477 aa)
	Oxa1l	Mitochondrial inner membrane protein OXA1L. (433 aa)
	Bid	BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (194 aa)
	Tomm40	Mitochondrial import receptor subunit TOM40-like. (72 aa)
	CgPICR_014126	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (172 aa)
	I79_012103	Protein spire-like 1. (524 aa)
	Afg3l2	AFG3-like protein 2; Belongs to the AAA ATPase family. (506 aa)
	Tomm70	Mitochondrial import receptor subunit TOM70. (384 aa)
	I79_011971	FUN14 domain-containing protein 2. (150 aa)
	I79_011732	Coiled-coil domain-containing protein 56. (108 aa)
	Ghitm	Growth hormone-inducible transmembrane protein; Belongs to the BI1 family. (345 aa)
	Ccdc51	Coiled-coil domain-containing protein 51. (242 aa)
	Pisd	Phosphatidylserine decarboxylase proenzyme. (235 aa)
	I79_011111	Phosphatidylserine decarboxylase proenzyme. (200 aa)
	Prr14l	Uncharacterized protein C22orf30. (1956 aa)
	I79_010854	MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (716 aa)
	Micu1	Calcium-binding atopy-related autoantigen 1. (477 aa)
	Mcu	Coiled-coil domain-containing protein 109A. (219 aa)
	Chchd3	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (227 aa)
	Agk	Acylglycerol kinase, mitochondrial. (421 aa)
	I79_008836	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (117 aa)
	Micos13	MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (119 aa)
	Rhot2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (620 aa)
	Mgarp	Uncharacterized protein C4orf49. (103 aa)
	Fis1	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
	Pink1	Serine/threonine-protein kinase PINK1, mitochondrial. (451 aa)
	Mul1	Mitochondrial ubiquitin ligase activator of NFKB 1. (321 aa)
	Tmem70	Transmembrane protein 70, mitochondrial. (111 aa)
	I79_006971	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (66 aa)
	I79_006440	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (380 aa)
	Adck1	Uncharacterized aarF domain-containing protein kinase 1. (523 aa)
	Tmem177	Transmembrane protein 177. (240 aa)
	Timm17a	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (171 aa)
	I79_004214	FUN14 domain-containing protein 1. (136 aa)
	I79_004042	Cytochrome c oxidase assembly protein COX16-like, mitochondrial. (163 aa)
	Synj2bp	Synaptojanin-2-binding protein. (215 aa)
	I79_003945	Cytochrome c oxidase assembly protein COX11, mitochondrial. (142 aa)
	Sfxn1	Sidoreflexin. (340 aa)
	I79_003611	Coiled-coil domain-containing protein 90A, mitochondrial. (211 aa)
	I79_003092	Protein SCO1-like, mitochondrial. (190 aa)
	Ptpmt1	Protein-tyrosine phosphatase mitochondrial 1. (126 aa)
	Abcb10	ATP-binding cassette sub-family B member 10, mitochondrial. (283 aa)
	Tomm20	Mitochondrial import receptor subunit TOM20-like. (145 aa)
	Tmem11	Transmembrane protein 11. (176 aa)
	Tmem199	Transmembrane protein 199. (208 aa)
	Slc25a19	Mitochondrial thiamine pyrophosphate carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
	I79_000677	Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (415 aa)
	Mpc1l	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (92 aa)
	Chchd6	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (272 aa)
	Spg7	Paraplegin. (781 aa)
	H671_3g8729	AFG3-like protein 1. (789 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abcb10	Abcb6	G3GX20	G3HWF4	ATP-binding cassette sub-family B member 10, mitochondrial.	ATP-binding cassette sub-family B member 6, mitochondrial.	0.475
Abcb10	Ccdc51	G3GX20	G3HKQ1	ATP-binding cassette sub-family B member 10, mitochondrial.	Coiled-coil domain-containing protein 51.	0.410
Abcb10	Ppox	G3GX20	G3HU16	ATP-binding cassette sub-family B member 10, mitochondrial.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.621
Abcb10	Spg7	G3GX20	G3GRR9	ATP-binding cassette sub-family B member 10, mitochondrial.	Paraplegin.	0.653
Abcb6	Abcb10	G3HWF4	G3GX20	ATP-binding cassette sub-family B member 6, mitochondrial.	ATP-binding cassette sub-family B member 10, mitochondrial.	0.475
Abcb6	Ppox	G3HWF4	G3HU16	ATP-binding cassette sub-family B member 6, mitochondrial.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.829
Afg3l2	H671_3g8729	G3HMW9	G3GRP9	AFG3-like protein 2; Belongs to the AAA ATPase family.	AFG3-like protein 1.	0.927
Afg3l2	Mcu	G3HMW9	G3HJ27	AFG3-like protein 2; Belongs to the AAA ATPase family.	Coiled-coil domain-containing protein 109A.	0.607
Afg3l2	Micu1	G3HMW9	G3HJ28	AFG3-like protein 2; Belongs to the AAA ATPase family.	Calcium-binding atopy-related autoantigen 1.	0.640
Afg3l2	Smdt1	G3HMW9	G3I0F5	AFG3-like protein 2; Belongs to the AAA ATPase family.	UPF0466 protein C22orf32-like, mitochondrial.	0.748
Afg3l2	Spg7	G3HMW9	G3GRR9	AFG3-like protein 2; Belongs to the AAA ATPase family.	Paraplegin.	0.774
Apool	Chchd3	G3IDU3	G3HH22	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.909
Apool	Chchd6	G3IDU3	G3GRZ5	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.901
Apool	Dnajc11	G3IDU3	G3I4U4	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	DnaJ-like subfamily C member 11.	0.626
Apool	I79_010854	G3IDU3	G3HJK8	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.865
Apool	Micos10	G3IDU3	G3HU30	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.858
Apool	Micos13	G3IDU3	G3HCJ0	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.873
Apool	Tmem11	G3IDU3	G3GVI5	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	Transmembrane protein 11.	0.615
Bak1	Bid	A1E3K4	G3HQ86	Bcl-2-likeous antagonist/killer.	BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.	0.998
Bid	Bak1	G3HQ86	A1E3K4	BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.	Bcl-2-likeous antagonist/killer.	0.998