STRINGSTRING
Ncoa3 Ncoa3 I79_006792 I79_006792 Nodal Nodal I79_005864 I79_005864 Smarca4 Smarca4 Igf1 Igf1 Med1 Med1 I79_005358 I79_005358 I79_005195 I79_005195 I79_005032 I79_005032 Lats1 Lats1 I79_004452 I79_004452 H671_3g8832 H671_3g8832 I79_003898 I79_003898 Uba5 Uba5 Cry2 Cry2 Vamp2 Vamp2 I79_002659 I79_002659 Src Src Rnf6 Rnf6 Lbh Lbh I79_001744 I79_001744 Ncor1 Ncor1 I79_001484 I79_001484 Phb2 Phb2 Tp63 Tp63 I79_000801 I79_000801 Foxp1 Foxp1 Pak1 Pak1 Ar Ar I79_023104 I79_023104 I79_024164 I79_024164 I79_024481 I79_024481 I79_021577 I79_021577 Vps18 Vps18 Tcf21 Tcf21 Vps11 Vps11 I79_019839 I79_019839 I79_019797 I79_019797 Ntrk2 Ntrk2 Foxa1 Foxa1 I79_019663 I79_019663 I79_019286 I79_019286 I79_019113 I79_019113 Kmt2d Kmt2d Hif3a Hif3a Ep300 Ep300 Pagr1 Pagr1 Ufsp2 Ufsp2 I79_017776 I79_017776 Cnot1 Cnot1 Rnf14 Rnf14 Nr0b1 Nr0b1 Ncor2 Ncor2 Foxh1 Foxh1 Cnot9 Cnot9 I79_014940 I79_014940 Parp1 Parp1 Wbp2 Wbp2 I79_013438 I79_013438 Cry1 Cry1 Heyl Heyl Brca1 Brca1 Skp2 Skp2 Phb Phb I79_010864 I79_010864 Znf366 Znf366 Sfrp1 Sfrp1 I79_009834 I79_009834 Hand1 Hand1 Calr Calr Ddx5 Ddx5 Safb2 Safb2 I79_007385 I79_007385 Pias2 Pias2 Sirt1 Sirt1 I79_007329 I79_007329 I79_007328 I79_007328 Lmo3 Lmo3 I79_006924 I79_006924 I79_006923 I79_006923 Hdac1 Hdac1 Prmt2 Prmt2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ncoa3Nuclear receptor coactivator 3. (1211 aa)
I79_006792DUF1518 domain-containing protein. (200 aa)
NodalNodal. (309 aa)
I79_005864Histone-arginine methyltransferase CARM1. (94 aa)
Smarca4Putative global transcription activator SNF2L4. (1614 aa)
Igf1Insulin-like growth factor I. (75 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
I79_005358Estrogen receptor beta. (58 aa)
I79_005195Striatin-3. (593 aa)
I79_005032DDRGK domain-containing protein 1. (345 aa)
Lats1Serine/threonine-protein kinase LATS1. (1130 aa)
I79_004452Prohibitin. (131 aa)
H671_3g8832E3 ubiquitin-protein ligase. (169 aa)
I79_003898RING finger protein 6. (477 aa)
Uba5Ubiquitin-like modifier-activating enzyme 5. (359 aa)
Cry2Cryptochrome-2. (577 aa)
Vamp2Period circadian protein-like 1. (1281 aa)
I79_002659High mobility group protein HMGI-C. (103 aa)
SrcTyrosine-protein kinase. (536 aa)
Rnf6E3 ubiquitin-protein ligase. (666 aa)
LbhProtein LBH. (88 aa)
I79_001744Nuclear receptor corepressor 1. (680 aa)
Ncor1Nuclear receptor corepressor 1. (1591 aa)
I79_00148465 kDa Yes-associated protein. (257 aa)
Phb2Prohibitin-2. (396 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (642 aa)
I79_000801Histone deacetylase 1. (92 aa)
Foxp1Forkhead box protein P1. (696 aa)
Pak1Serine/threonine-protein kinase PAK 1. (325 aa)
ArAndrogen receptor. (517 aa)
I79_023104CCR4-NOT transcription complex subunit 2. (417 aa)
I79_024164Tripartite motif-containing protein 68. (455 aa)
I79_024481Prohibitin. (274 aa)
I79_021577Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (248 aa)
Vps18Vacuolar protein sorting-associated protein 18-like. (973 aa)
Tcf21Transcription factor 21. (179 aa)
Vps11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (965 aa)
I79_019839Nuclear receptor coactivator. (1413 aa)
I79_019797BDNF/NT-3 growth factors receptor. (192 aa)
Ntrk2Tyrosine-protein kinase receptor. (383 aa)
Foxa1Hepatocyte nuclear factor 3-alpha. (434 aa)
I79_01966325-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (216 aa)
I79_019286Androgen receptor. (295 aa)
I79_019113Histone-lysine N-methyltransferase MLL2. (1475 aa)
Kmt2dHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (4002 aa)
Hif3aSerine/threonine-protein phosphatase 5. (607 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
Pagr1PAXIP1-associated protein 1. (251 aa)
Ufsp2Ufm1-specific protease 2. (461 aa)
I79_017776CCR4-NOT transcription complex subunit 1. (660 aa)
Cnot1CCR4-NOT transcription complex subunit 1. (1520 aa)
Rnf14RBR-type E3 ubiquitin transferase. (420 aa)
Nr0b1Nuclear receptor subfamily 0 group B member 1. (470 aa)
Ncor2Nuclear receptor corepressor 2. (2530 aa)
Foxh1Forkhead box protein H1. (367 aa)
Cnot9Cell differentiation protein RCD1-like. (299 aa)
I79_014940Prohibitin. (85 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (971 aa)
Wbp2WW domain-binding protein 2. (261 aa)
I79_013438Prohibitin. (132 aa)
Cry1Cryptochrome-1. (428 aa)
HeylHairy/enhancer-of-split related with YRPW motif-like protein. (300 aa)
Brca1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1790 aa)
Skp2S-phase kinase-associated protein 2. (424 aa)
PhbProhibitin. (272 aa)
I79_010864Growth hormone-releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (372 aa)
Znf366Zinc finger protein 366. (726 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_009834Disabled-like 2. (705 aa)
Hand1Heart-and neural crest derivatives-expressed protein 1. (94 aa)
CalrCalreticulin. (417 aa)
Ddx5Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (615 aa)
Safb2Scaffold attachment factor B2. (1198 aa)
I79_007385E3 SUMO-protein ligase PIAS2. (116 aa)
Pias2E3 SUMO-protein ligase PIAS2. (157 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_007329Histone deacetylase 1. (250 aa)
I79_007328Histone deacetylase 2. (91 aa)
Lmo3LIM domain only protein 3. (149 aa)
I79_006924Histone deacetylase 1. (188 aa)
I79_006923Histone deacetylase 1. (235 aa)
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
Prmt2Protein arginine N-methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (445 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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