STRINGSTRING
Hdac1 Hdac1 Nodal Nodal Smarca4 Smarca4 Igf1 Igf1 I79_005358 I79_005358 I79_005195 I79_005195 I79_004452 I79_004452 Cry2 Cry2 Vamp2 Vamp2 I79_002659 I79_002659 Lbh Lbh I79_001744 I79_001744 Ncor1 Ncor1 Foxp1 Foxp1 Phb2 Phb2 Tp63 Tp63 I79_000801 I79_000801 Vps11 Vps11 I79_019663 I79_019663 I79_017776 I79_017776 Cnot1 Cnot1 Nr0b1 Nr0b1 Ncor2 Ncor2 Foxh1 Foxh1 Cnot9 Cnot9 I79_014940 I79_014940 I79_013438 I79_013438 Cry1 Cry1 Heyl Heyl Brca1 Brca1 I79_024481 I79_024481 I79_023104 I79_023104 Vps18 Vps18 Tcf21 Tcf21 Phb Phb Znf366 Znf366 Sfrp1 Sfrp1 I79_009834 I79_009834 Calr Calr I79_007385 I79_007385 Pias2 Pias2 Sirt1 Sirt1 I79_007329 I79_007329 I79_007328 I79_007328 I79_006924 I79_006924 I79_006923 I79_006923
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
NodalNodal. (309 aa)
Smarca4Putative global transcription activator SNF2L4. (1614 aa)
Igf1Insulin-like growth factor I. (75 aa)
I79_005358Estrogen receptor beta. (58 aa)
I79_005195Striatin-3. (593 aa)
I79_004452Prohibitin. (131 aa)
Cry2Cryptochrome-2. (577 aa)
Vamp2Period circadian protein-like 1. (1281 aa)
I79_002659High mobility group protein HMGI-C. (103 aa)
LbhProtein LBH. (88 aa)
I79_001744Nuclear receptor corepressor 1. (680 aa)
Ncor1Nuclear receptor corepressor 1. (1591 aa)
Foxp1Forkhead box protein P1. (696 aa)
Phb2Prohibitin-2. (396 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (642 aa)
I79_000801Histone deacetylase 1. (92 aa)
Vps11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (965 aa)
I79_01966325-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (216 aa)
I79_017776CCR4-NOT transcription complex subunit 1. (660 aa)
Cnot1CCR4-NOT transcription complex subunit 1. (1520 aa)
Nr0b1Nuclear receptor subfamily 0 group B member 1. (470 aa)
Ncor2Nuclear receptor corepressor 2. (2530 aa)
Foxh1Forkhead box protein H1. (367 aa)
Cnot9Cell differentiation protein RCD1-like. (299 aa)
I79_014940Prohibitin. (85 aa)
I79_013438Prohibitin. (132 aa)
Cry1Cryptochrome-1. (428 aa)
HeylHairy/enhancer-of-split related with YRPW motif-like protein. (300 aa)
Brca1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1790 aa)
I79_024481Prohibitin. (274 aa)
I79_023104CCR4-NOT transcription complex subunit 2. (417 aa)
Vps18Vacuolar protein sorting-associated protein 18-like. (973 aa)
Tcf21Transcription factor 21. (179 aa)
PhbProhibitin. (272 aa)
Znf366Zinc finger protein 366. (726 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_009834Disabled-like 2. (705 aa)
CalrCalreticulin. (417 aa)
I79_007385E3 SUMO-protein ligase PIAS2. (116 aa)
Pias2E3 SUMO-protein ligase PIAS2. (157 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_007329Histone deacetylase 1. (250 aa)
I79_007328Histone deacetylase 2. (91 aa)
I79_006924Histone deacetylase 1. (188 aa)
I79_006923Histone deacetylase 1. (235 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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