(14 nodes) Positive regulation of intracellular estrogen receptor signaling pathway network (Cricetulus griseus)

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second shell of interactors

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Known Interactions

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Your Input:
	Ar	Androgen receptor. (517 aa)
	Foxa1	Hepatocyte nuclear factor 3-alpha. (434 aa)
	I79_019286	Androgen receptor. (295 aa)
	I79_019113	Histone-lysine N-methyltransferase MLL2. (1475 aa)
	Kmt2d	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (4002 aa)
	Pagr1	PAXIP1-associated protein 1. (251 aa)
	Parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (971 aa)
	Wbp2	WW domain-binding protein 2. (261 aa)
	Skp2	S-phase kinase-associated protein 2. (424 aa)
	Ncoa3	Nuclear receptor coactivator 3. (1211 aa)
	Med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
	I79_001484	65 kDa Yes-associated protein. (257 aa)
	I79_006792	DUF1518 domain-containing protein. (200 aa)
	Pak1	Serine/threonine-protein kinase PAK 1. (325 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ar	Foxa1	G3IGU9	G3I810	Androgen receptor.	Hepatocyte nuclear factor 3-alpha.	0.745
Ar	I79_006792	G3IGU9	G3H8T1	Androgen receptor.	DUF1518 domain-containing protein.	0.790
Ar	I79_019286	G3IGU9	G3I705	Androgen receptor.	Androgen receptor.	0.915
Ar	Med1	G3IGU9	G3H5X2	Androgen receptor.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.485
Ar	Ncoa3	G3IGU9	G3H8T2	Androgen receptor.	Nuclear receptor coactivator 3.	0.790
Foxa1	Ar	G3I810	G3IGU9	Hepatocyte nuclear factor 3-alpha.	Androgen receptor.	0.745
Foxa1	I79_006792	G3I810	G3H8T1	Hepatocyte nuclear factor 3-alpha.	DUF1518 domain-containing protein.	0.460
Foxa1	I79_019286	G3I810	G3I705	Hepatocyte nuclear factor 3-alpha.	Androgen receptor.	0.745
Foxa1	Ncoa3	G3I810	G3H8T2	Hepatocyte nuclear factor 3-alpha.	Nuclear receptor coactivator 3.	0.551
I79_001484	Wbp2	G3GUW0	G3HTV2	65 kDa Yes-associated protein.	WW domain-binding protein 2.	0.645
I79_006792	Ar	G3H8T1	G3IGU9	DUF1518 domain-containing protein.	Androgen receptor.	0.790
I79_006792	Foxa1	G3H8T1	G3I810	DUF1518 domain-containing protein.	Hepatocyte nuclear factor 3-alpha.	0.460
I79_006792	I79_019286	G3H8T1	G3I705	DUF1518 domain-containing protein.	Androgen receptor.	0.790
I79_006792	Med1	G3H8T1	G3H5X2	DUF1518 domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.606
I79_006792	Ncoa3	G3H8T1	G3H8T2	DUF1518 domain-containing protein.	Nuclear receptor coactivator 3.	0.941
I79_019113	Kmt2d	G3I6I9	G3I6I8	Histone-lysine N-methyltransferase MLL2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.920
I79_019113	Pagr1	G3I6I9	G3I4J0	Histone-lysine N-methyltransferase MLL2.	PAXIP1-associated protein 1.	0.603
I79_019286	Ar	G3I705	G3IGU9	Androgen receptor.	Androgen receptor.	0.915
I79_019286	Foxa1	G3I705	G3I810	Androgen receptor.	Hepatocyte nuclear factor 3-alpha.	0.745
I79_019286	I79_006792	G3I705	G3H8T1	Androgen receptor.	DUF1518 domain-containing protein.	0.790