STRINGSTRING
Ppard Ppard Pitx2 Pitx2 Tyms Tyms I79_022023 I79_022023 Epo Epo I79_018785 I79_018785 Serpina7 Serpina7 I79_015041 I79_015041 PPARG PPARG I79_013067 I79_013067 I79_012903 I79_012903 Tshb Tshb Map1b Map1b I79_006978 I79_006978 Lrat Lrat Slc34a1 Slc34a1 Cat Cat Aldh1a2 Aldh1a2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
Pitx2Homeobox protein. (322 aa)
TymsThymidylate synthase-like protein. (307 aa)
I79_022023Arginase-1; Belongs to the arginase family. (281 aa)
EpoErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
I79_018785Retinoic acid receptor alpha. (484 aa)
Serpina7Thyroxine-binding globulin; Belongs to the serpin family. (418 aa)
I79_015041Thymidylate synthase. (192 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
I79_013067Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (443 aa)
I79_012903Pulmonary surfactant-associated protein A. (238 aa)
TshbThyrotropin subunit beta-like protein. (138 aa)
Map1bMicrotubule-associated protein 1B. (2371 aa)
I79_006978Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (379 aa)
LratLecithin retinol acyltransferase-like protein. (227 aa)
Slc34a1Sodium-dependent phosphate transport protein 2A. (629 aa)
CatCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (555 aa)
Aldh1a2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (460 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.