STRINGSTRING
Areg Areg Ccnd1 Ccnd1 Phb2 Phb2 Wnt5a Wnt5a Med1 Med1 Tfap2c Tfap2c I79_009500 I79_009500 Iqgap3 Iqgap3 Tnfsf11 Tnfsf11 I79_010613 I79_010613 I79_011789 I79_011789 Stat6 Stat6 Agap2 Agap2 Chuk Chuk Btrc Btrc Epha2 Epha2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AregAmphiregulin. (230 aa)
Ccnd1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
Phb2Prohibitin-2. (396 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
Tfap2cTranscription factor AP-2 gamma. (463 aa)
I79_009500Mitogen-activated protein kinase 1. (68 aa)
Iqgap3Ras GTPase-activating-like protein IQGAP3. (1633 aa)
Tnfsf11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (199 aa)
I79_010613Transcription factor AP-2 gamma. (236 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
Stat6Signal transducer and activator of transcription. (844 aa)
Agap2Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2. (829 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha. (647 aa)
BtrcF-box/WD repeat-containing protein 1A. (488 aa)
Epha2Ephrin type-A receptor 2. (942 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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