(21 nodes) Apolipoprotein binding network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Lipc	Hepatic triacylglycerol lipase. (470 aa)
	I79_025812	Microtubule-associated protein. (128 aa)
	I79_025297	Very low-density lipoprotein receptor. (558 aa)
	I79_024407	60 kDa heat shock protein, mitochondrial. (214 aa)
	I79_022300	60 kDa heat shock protein, mitochondrial. (252 aa)
	I79_019042	60 kDa heat shock protein, mitochondrial. (169 aa)
	H671_3g9603	60 kDa heat shock protein, mitochondrial. (141 aa)
	Scarb1	Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
	Lrp1	Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
	Canx	Calnexin. (591 aa)
	App	Amyloid beta A4 protein. (433 aa)
	Hspd1	60 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (526 aa)
	Lcat	Phosphatidylcholine-sterol acyltransferase. (183 aa)
	I79_009796	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily. (697 aa)
	Lrp6	Low-density lipoprotein receptor-related protein 6. (565 aa)
	I79_007641	Low-density lipoprotein receptor-related protein 6. (543 aa)
	Lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (450 aa)
	I79_003972	60 kDa heat shock protein, mitochondrial; Belongs to the TCP-1 chaperonin family. (104 aa)
	Abca1	ATP-binding cassette sub-family A member 1. (2261 aa)
	I79_001015	Low-density lipoprotein receptor-related protein 8. (764 aa)
	Pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (691 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abca1	Lcat	G3GTZ6	G3HKW5	ATP-binding cassette sub-family A member 1.	Phosphatidylcholine-sterol acyltransferase.	0.776
Abca1	Lipc	G3GTZ6	G3GRM1	ATP-binding cassette sub-family A member 1.	Hepatic triacylglycerol lipase.	0.509
Abca1	Lpl	G3GTZ6	G3H6V7	ATP-binding cassette sub-family A member 1.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.480
Abca1	Pcsk9	G3GTZ6	G3GTK5	ATP-binding cassette sub-family A member 1.	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	0.773
Abca1	Scarb1	G3GTZ6	G3HX53	ATP-binding cassette sub-family A member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.696
App	I79_001015	G3HMG4	G3GTN0	Amyloid beta A4 protein.	Low-density lipoprotein receptor-related protein 8.	0.562
App	I79_007641	G3HMG4	G3HB26	Amyloid beta A4 protein.	Low-density lipoprotein receptor-related protein 6.	0.452
App	I79_009796	G3HMG4	G3HGQ6	Amyloid beta A4 protein.	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.505
App	I79_025297	G3HMG4	G3IMZ0	Amyloid beta A4 protein.	Very low-density lipoprotein receptor.	0.473
App	I79_025812	G3HMG4	G3IPA6	Amyloid beta A4 protein.	Microtubule-associated protein.	0.788
App	Lrp1	G3HMG4	G3HW34	Amyloid beta A4 protein.	Prolow-density lipoprotein receptor-related protein 1.	0.648
App	Lrp6	G3HMG4	G3HB27	Amyloid beta A4 protein.	Low-density lipoprotein receptor-related protein 6.	0.452
App	Scarb1	G3HMG4	G3HX53	Amyloid beta A4 protein.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.484
H671_3g9603	I79_003972	G3I1J0	G3H1E7	60 kDa heat shock protein, mitochondrial.	60 kDa heat shock protein, mitochondrial; Belongs to the TCP-1 chaperonin family.	0.950
I79_001015	App	G3GTN0	G3HMG4	Low-density lipoprotein receptor-related protein 8.	Amyloid beta A4 protein.	0.562
I79_001015	I79_025297	G3GTN0	G3IMZ0	Low-density lipoprotein receptor-related protein 8.	Very low-density lipoprotein receptor.	0.610
I79_001015	Lipc	G3GTN0	G3GRM1	Low-density lipoprotein receptor-related protein 8.	Hepatic triacylglycerol lipase.	0.418
I79_001015	Pcsk9	G3GTN0	G3GTK5	Low-density lipoprotein receptor-related protein 8.	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	0.768
I79_003972	H671_3g9603	G3H1E7	G3I1J0	60 kDa heat shock protein, mitochondrial; Belongs to the TCP-1 chaperonin family.	60 kDa heat shock protein, mitochondrial.	0.950
I79_003972	I79_019042	G3H1E7	G3I6C6	60 kDa heat shock protein, mitochondrial; Belongs to the TCP-1 chaperonin family.	60 kDa heat shock protein, mitochondrial.	0.951