(15 nodes) High-density lipoprotein particle remodeling network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Apoc3	Apolipoprotein C-III. (76 aa)
	CgPICR_005982	Apolipoprotein A-IV. (230 aa)
	Lcat	Phosphatidylcholine-sterol acyltransferase. (183 aa)
	Scarb1	Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
	CETP	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (492 aa)
	Pltp	Phospholipid transfer protein. (493 aa)
	Lipc	Hepatic triacylglycerol lipase. (470 aa)
	Apoa2	Apolipoprotein A-II-like protein. (101 aa)
	Abcg1	ATP-binding cassette sub-family G member 1. (647 aa)
	Lipg	Endothelial lipase. (543 aa)
	Apoe	Apolipoprotein E. (313 aa)
	I79_016465	Apolipoprotein M. (56 aa)
	Apom	Apolipoprotein M. (90 aa)
	Pla2g3	Group 3 secretory phospholipase A2. (398 aa)
	Apoa1	Apolipoprotein A-I. (264 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abcg1	Apoa2	G3HLD6	G3HTY7	ATP-binding cassette sub-family G member 1.	Apolipoprotein A-II-like protein.	0.499
Abcg1	Apoe	G3HLD6	G3HPC9	ATP-binding cassette sub-family G member 1.	Apolipoprotein E.	0.816
Abcg1	CETP	G3HLD6	G3HIK4	ATP-binding cassette sub-family G member 1.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.748
Abcg1	Lcat	G3HLD6	G3HKW5	ATP-binding cassette sub-family G member 1.	Phosphatidylcholine-sterol acyltransferase.	0.535
Abcg1	Lipg	G3HLD6	G3HQJ0	ATP-binding cassette sub-family G member 1.	Endothelial lipase.	0.421
Abcg1	Pltp	G3HLD6	G3H8V4	ATP-binding cassette sub-family G member 1.	Phospholipid transfer protein.	0.732
Abcg1	Scarb1	G3HLD6	G3HX53	ATP-binding cassette sub-family G member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.624
Apoa1	Apoa2	G3I7Q1	G3HTY7	Apolipoprotein A-I.	Apolipoprotein A-II-like protein.	0.834
Apoa1	Apoc3	G3I7Q1	G3I7Q2	Apolipoprotein A-I.	Apolipoprotein C-III.	0.660
Apoa1	Apoe	G3I7Q1	G3HPC9	Apolipoprotein A-I.	Apolipoprotein E.	0.849
Apoa1	CETP	G3I7Q1	G3HIK4	Apolipoprotein A-I.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.746
Apoa1	CgPICR_005982	G3I7Q1	G3I7Q3	Apolipoprotein A-I.	Apolipoprotein A-IV.	0.745
Apoa1	Lcat	G3I7Q1	G3HKW5	Apolipoprotein A-I.	Phosphatidylcholine-sterol acyltransferase.	0.964
Apoa1	Pltp	G3I7Q1	G3H8V4	Apolipoprotein A-I.	Phospholipid transfer protein.	0.774
Apoa1	Scarb1	G3I7Q1	G3HX53	Apolipoprotein A-I.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.406
Apoa2	Abcg1	G3HTY7	G3HLD6	Apolipoprotein A-II-like protein.	ATP-binding cassette sub-family G member 1.	0.499
Apoa2	Apoa1	G3HTY7	G3I7Q1	Apolipoprotein A-II-like protein.	Apolipoprotein A-I.	0.834
Apoa2	Apoc3	G3HTY7	G3I7Q2	Apolipoprotein A-II-like protein.	Apolipoprotein C-III.	0.978
Apoa2	Apoe	G3HTY7	G3HPC9	Apolipoprotein A-II-like protein.	Apolipoprotein E.	0.957
Apoa2	Apom	G3HTY7	G3HZG5	Apolipoprotein A-II-like protein.	Apolipoprotein M.	0.794