(39 nodes) Protein localization to cell surface network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Emp2	Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (174 aa)
	I79_022455	Receptor-type tyrosine-protein phosphatase kappa. (375 aa)
	Ank2	Ankyrin-2. (3299 aa)
	I79_021870	CD177 antigen. (106 aa)
	I79_021283	Angiopoietin-1. (298 aa)
	Flna	Filamin-A. (2488 aa)
	Fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	I79_020548	Receptor-type tyrosine-protein phosphatase kappa. (858 aa)
	Mesd	LDLR chaperone MESD. (226 aa)
	Stx4	Syntaxin-4; Belongs to the syntaxin family. (298 aa)
	I79_018947	Protein RIC-3. (251 aa)
	I79_018733	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1. (247 aa)
	Gga1	ADP-ribosylation factor-binding protein GGA1. (430 aa)
	I79_017280	Astrotactin-2. (267 aa)
	Rab11a	Ras-related protein Rab-11A. (216 aa)
	Washc1	WAS protein family-like 1. (497 aa)
	Smurf1	E3 ubiquitin-protein ligase SMURF1. (303 aa)
	Wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	I79_012057	Astrotactin-2. (984 aa)
	Slc28a2	Sodium/nucleoside cotransporter 2. (625 aa)
	Tsc2	Tuberin. (1546 aa)
	I79_007548	Angiopoietin-1. (112 aa)
	Pigu	Phosphatidylinositol glycan anchor biosynthesis class U protein. (435 aa)
	Ctnnb1	Catenin beta-1. (781 aa)
	Usp4	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (940 aa)
	Ap3b1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1091 aa)
	Ptpru	Receptor-type tyrosine-protein phosphatase U. (144 aa)
	Unc50	Protein unc-50-like. (144 aa)
	I79_002759	Neuroligin-2. (635 aa)
	Vcl	Vinculin. (1143 aa)
	I79_022876	ADP-ribosylation factor-binding protein GGA2. (93 aa)
	PIGK	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (317 aa)
	Jam3	Junctional adhesion molecule C. (286 aa)
	Gga3	ADP-ribosylation factor-binding protein GGA3. (685 aa)
	Arf6	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	I79_025018	Ankyrin-2. (85 aa)
	I79_024443	CD177 antigen. (158 aa)
	I79_024153	Ficolin-2. (290 aa)
	I79_023780	ADP-ribosylation factor-binding protein GGA2. (437 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arf6	Gga1	G3IMU0	G3I4Z5	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor-binding protein GGA1.	0.615
Arf6	Gga3	G3IMU0	G3GTE9	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor-binding protein GGA3.	0.940
Arf6	I79_022876	G3IMU0	G3IGG3	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor-binding protein GGA2.	0.426
Arf6	I79_023780	G3IMU0	G3IIV2	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor-binding protein GGA2.	0.426
Arf6	Rab11a	G3IMU0	G3I0B0	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Ras-related protein Rab-11A.	0.558
Ctnnb1	Ptpru	G3H996	G3H1X6	Catenin beta-1.	Receptor-type tyrosine-protein phosphatase U.	0.459
Ctnnb1	Rab11a	G3H996	G3I0B0	Catenin beta-1.	Ras-related protein Rab-11A.	0.410
Ctnnb1	Smurf1	G3H996	G3HY97	Catenin beta-1.	E3 ubiquitin-protein ligase SMURF1.	0.412
Ctnnb1	Vcl	G3H996	G3GWQ1	Catenin beta-1.	Vinculin.	0.817
Ctnnb1	Wnt11	G3H996	G3HUR9	Catenin beta-1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.608
Fgf7	I79_007548	G3IAS3	G3HAT9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Angiopoietin-1.	0.538
Fgf7	I79_021283	G3IAS3	G3IC93	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Angiopoietin-1.	0.538
Flna	Vcl	G3IBK2	G3GWQ1	Filamin-A.	Vinculin.	0.910
Gga1	Arf6	G3I4Z5	G3IMU0	ADP-ribosylation factor-binding protein GGA1.	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.615
Gga1	Gga3	G3I4Z5	G3GTE9	ADP-ribosylation factor-binding protein GGA1.	ADP-ribosylation factor-binding protein GGA3.	0.959
Gga1	I79_022876	G3I4Z5	G3IGG3	ADP-ribosylation factor-binding protein GGA1.	ADP-ribosylation factor-binding protein GGA2.	0.472
Gga1	I79_023780	G3I4Z5	G3IIV2	ADP-ribosylation factor-binding protein GGA1.	ADP-ribosylation factor-binding protein GGA2.	0.945
Gga1	Rab11a	G3I4Z5	G3I0B0	ADP-ribosylation factor-binding protein GGA1.	Ras-related protein Rab-11A.	0.485
Gga3	Arf6	G3GTE9	G3IMU0	ADP-ribosylation factor-binding protein GGA3.	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.940
Gga3	Gga1	G3GTE9	G3I4Z5	ADP-ribosylation factor-binding protein GGA3.	ADP-ribosylation factor-binding protein GGA1.	0.959