STRINGSTRING
I79_004403 I79_004403 I79_004339 I79_004339 Vdac1 Vdac1 Kcnab1 Kcnab1 Grk6 Grk6 I79_003855 I79_003855 Cav3 Cav3 I79_003549 I79_003549 Fkbp1b Fkbp1b Tlr9 Tlr9 Lep Lep I79_002826 I79_002826 I79_002669 I79_002669 Ahi1 Ahi1 Prkce Prkce I79_001592 I79_001592 Nos1 Nos1 Pcsk9 Pcsk9 Slc9a3r1 Slc9a3r1 Ostn Ostn Fgf12 Fgf12 Kcne2 Kcne2 Arl6ip5 Arl6ip5 I79_000157 I79_000157 Gnb5 Gnb5 I79_000092 I79_000092 Casq2 Casq2 Fgf14 Fgf14 Bin1 Bin1 H671_1g2968 H671_1g2968 I79_011426 I79_011426 I79_011427 I79_011427 I79_011471 I79_011471 CgPICR_001891 CgPICR_001891 Pik3c2a Pik3c2a I79_012168 I79_012168 Cacna1f Cacna1f I79_012251 I79_012251 Akt2 Akt2 Atp7a Atp7a I79_012744 I79_012744 I79_013066 I79_013066 I79_013208 I79_013208 I79_013397 I79_013397 Slc43a1 Slc43a1 Sri Sri Grp Grp I79_013769 I79_013769 I79_013771 I79_013771 I79_013786 I79_013786 I79_013817 I79_013817 CgPICR_017756 CgPICR_017756 Inpp5k Inpp5k Ahr Ahr Gopc Gopc I79_014549 I79_014549 I79_014999 I79_014999 I79_015274 I79_015274 Actn2 Actn2 I79_015685 I79_015685 Tnf Tnf I79_016547 I79_016547 Ppp2ca Ppp2ca Gsk3a Gsk3a IL1B IL1B I79_017273 I79_017273 Drd4 Drd4 Agrn Agrn Fabp5 Fabp5 I79_018586 I79_018586 CgPICR_012539 CgPICR_012539 Slc30a1 Slc30a1 I79_018847 I79_018847 Epo Epo Cacnb3 Cacnb3 Rrad Rrad C1H4orf3 C1H4orf3 Prkcb Prkcb Stpg4 Stpg4 I79_020178 I79_020178 Kcne3 Kcne3 Tgfb1 Tgfb1 Enpp1 Enpp1 I79_020705 I79_020705 I79_020786 I79_020786 Oprl1 Oprl1 I79_021319 I79_021319 Hecw2 Hecw2 Sigirr Sigirr Mtor Mtor Ywhaq Ywhaq I79_022301 I79_022301 Tmbim6 Tmbim6 Snx27 Snx27 I79_022991 I79_022991 Kcne4 Kcne4 I79_023591 I79_023591 Oaz2 Oaz2 Slc43a2 Slc43a2 Stxbp3 Stxbp3 I79_024325 I79_024325 Irs2 Irs2 I79_024438 I79_024438 I79_024483 I79_024483 Cttnbp2nl Cttnbp2nl I79_024718 I79_024718 I79_024941 I79_024941 Pid1 Pid1 I79_025625 I79_025625 I79_025720 I79_025720 Myc Myc I79_026021 I79_026021 I79_026218 I79_026218 Ephb2 Ephb2 Iscu Iscu Gem Gem Thbs1 Thbs1 Ppif Ppif Ntsr1 Ntsr1 I79_009691 I79_009691 Slc6a9 Slc6a9 Stoml1 Stoml1 Rem1 Rem1 I79_008803 I79_008803 Commd1 Commd1 Osr1 Osr1 Prkca Prkca Calm2 Calm2 Kcnh2 Kcnh2 CgPICR_016658 CgPICR_016658 Sestd1 Sestd1 Cav1 Cav1 Mmp9 Mmp9 Atp1a2 Atp1a2 Pea15 Pea15 CgPICR_019210 CgPICR_019210 I79_006005 I79_006005 Gpr35 Gpr35 Rgs2 Rgs2 I79_005001 I79_005001 Akt1 Akt1 Crbn Crbn Drd2 Drd2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_004403D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
I79_004339Serine/threonine-protein phosphatase. (244 aa)
Vdac1Voltage-dependent anion-selective channel protein 1. (484 aa)
Kcnab1Voltage-gated potassium channel subunit beta-1. (109 aa)
Grk6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (551 aa)
I79_00385514-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa)
Cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
I79_003549D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa)
Fkbp1bPeptidylprolyl isomerase. (143 aa)
Tlr9Toll-like receptor 9. (1239 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
I79_002826Voltage-dependent anion-selective channel protein 1. (156 aa)
I79_002669Voltage-dependent anion-selective channel protein 1. (248 aa)
Ahi1Jouberin. (988 aa)
PrkceProtein kinase C epsilon type. (137 aa)
I79_001592Protein kinase C epsilon type. (163 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
Pcsk9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (691 aa)
Slc9a3r1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (354 aa)
OstnOsteocrin. (105 aa)
Fgf12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (165 aa)
Kcne2Potassium voltage-gated channel subfamily E member 2-like protein. (123 aa)
Arl6ip5PRA1 family protein. (188 aa)
I79_000157E3 ubiquitin-protein ligase NEDD4. (1032 aa)
Gnb5Guanine nucleotide-binding protein subunit beta-5. (353 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Casq2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (382 aa)
Fgf14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
Bin1Myc box-dependent-interacting protein 1. (522 aa)
H671_1g2968Putative kell blood group glycoprotein like protein. (555 aa)
I79_011426Experimental autoimmune prostatitis antigen 2-like. (649 aa)
I79_011427Protein FAM115C. (564 aa)
I79_01147114-3-3 protein theta; Belongs to the 14-3-3 family. (87 aa)
CgPICR_001891Glutathione S-transferase omega-1. (135 aa)
Pik3c2aPhosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide; Belongs to the PI3/PI4-kinase family. (637 aa)
I79_012168Fragile X mental retardation 1 protein. (560 aa)
Cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1387 aa)
I79_012251Voltage-dependent L-type calcium channel subunit alpha-1F. (211 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
Atp7aCopper-transporting ATPase 1. (1457 aa)
I79_012744Voltage-dependent anion-selective channel protein 1. (118 aa)
I79_013066Dysferlin. (1296 aa)
I79_013208Serine/threonine-protein kinase OSR1. (426 aa)
I79_013397GTP-binding protein REM 2. (317 aa)
Slc43a1Large neutral amino acids transporter small subunit 3. (607 aa)
SriSorcin. (117 aa)
GrpGastrin-releasing peptide. (75 aa)
I79_013769E3 ubiquitin-protein ligase NEDD4-like. (182 aa)
I79_013771Calcitonin. (206 aa)
I79_013786E3 ubiquitin-protein ligase HECW1. (1454 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
CgPICR_017756Calmodulin-like protein; Belongs to the calmodulin family. (98 aa)
Inpp5kInositol polyphosphate 5-phosphatase K. (451 aa)
AhrAryl hydrocarbon receptor. (247 aa)
GopcGolgi-associated PDZ and coiled-coil motif-containing protein. (424 aa)
I79_014549STE20/SPS1-related proline-alanine-rich protein kinase. (418 aa)
I79_014999Ankyrin-3. (1539 aa)
I79_015274Bax inhibitor 1; Belongs to the BI1 family. (56 aa)
Actn2Alpha-actinin-2. (122 aa)
I79_015685EF-hand domain-containing protein. (101 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
I79_016547DCC-interacting protein 13-beta. (634 aa)
Ppp2caSerine/threonine-protein phosphatase. (303 aa)
Gsk3aGlycogen synthase kinase-3 alpha. (653 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
I79_017273Protein kinase C alpha type. (128 aa)
Drd4D(4) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (387 aa)
AgrnAgrin. (2036 aa)
Fabp5Fatty acid-binding protein, epidermal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (101 aa)
I79_018586Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
CgPICR_012539Small ubiquitin-related modifier. (112 aa)
Slc30a1Zinc transporter 1. (284 aa)
I79_018847Calmodulin; Belongs to the calmodulin family. (152 aa)
EpoErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
Cacnb3Voltage-dependent L-type calcium channel subunit beta-3. (308 aa)
RradGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (305 aa)
C1H4orf3Uncharacterized protein C4orf3-like. (67 aa)
PrkcbNon-specific serine/threonine protein kinase. (544 aa)
Stpg4Calmodulin; Belongs to the calmodulin family. (211 aa)
I79_020178Voltage-dependent anion-selective channel protein 1. (194 aa)
Kcne3Potassium voltage-gated channel subfamily E member 3. (105 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
I79_020705Ubiquilin-1. (168 aa)
I79_020786Calmodulin; Belongs to the calmodulin family. (141 aa)
Oprl1Nociceptin receptor; Belongs to the G-protein coupled receptor 1 family. (367 aa)
I79_02131914-3-3 protein theta; Belongs to the 14-3-3 family. (191 aa)
Hecw2E3 ubiquitin-protein ligase HECW2. (85 aa)
SigirrAnoctamin. (1092 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
Ywhaq14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa)
I79_022301Calcium/calmodulin-dependent protein kinase type II delta chain. (225 aa)
Tmbim6Bax inhibitor 1; Belongs to the BI1 family. (237 aa)
Snx27Sorting nexin-27. (232 aa)
I79_022991Serine/threonine-protein kinase OSR1. (166 aa)
Kcne4Potassium voltage-gated channel subfamily E member 4. (170 aa)
I79_023591Peptidyl-prolyl cis-trans isomerase, mitochondrial. (317 aa)
Oaz2Ornithine decarboxylase antizyme 2. (60 aa)
Slc43a2Large neutral amino acids transporter small subunit 4. (217 aa)
Stxbp3Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)
I79_024325Voltage-dependent anion-selective channel protein 1. (91 aa)
Irs2Insulin receptor substrate 2. (465 aa)
I79_024438Glutathione S-transferase omega-1; Belongs to the GST superfamily. (318 aa)
I79_024483Polycystin-2. (192 aa)
Cttnbp2nlCTTNBP2NL. (638 aa)
I79_024718Glutathione S-transferase. (218 aa)
I79_024941Calmodulin; Belongs to the calmodulin family. (149 aa)
Pid1PTB-containing, cubilin and LRP1-interacting protein. (159 aa)
I79_025625Polycystin-2. (318 aa)
I79_025720Corticotropin-releasing factor receptor 1. (134 aa)
MycMyc proto-oncogene protein. (281 aa)
I79_02602114-3-3 protein epsilon; Belongs to the 14-3-3 family. (70 aa)
I79_026218Calcium/calmodulin-dependent protein kinase type II delta chain. (64 aa)
Ephb2Ephrin type-B receptor 2. (1018 aa)
IscuIron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (139 aa)
GemGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
Thbs1Thrombospondin-1. (533 aa)
PpifPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (206 aa)
Ntsr1Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
I79_009691Growth factor receptor-bound protein 10. (518 aa)
Slc6a9Sodium-and chloride-dependent glycine transporter 1. (180 aa)
Stoml1Stomatin-like protein 1. (400 aa)
Rem1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (297 aa)
I79_008803Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (557 aa)
Commd1COMM domain-containing protein 1. (188 aa)
Osr1Protein odd-skipped-related 1. (266 aa)
PrkcaNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
Calm2Calmodulin; Belongs to the calmodulin family. (161 aa)
Kcnh2Potassium voltage-gated channel subfamily H member 2. (1038 aa)
CgPICR_016658Voltage-dependent anion-selective channel protein 1. (129 aa)
Sestd1SEC14 domain and spectrin repeat-containing protein 1. (696 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Mmp9Matrix metalloproteinase-9. (710 aa)
Atp1a2Sodium/potassium-transporting ATPase subunit alpha-2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1194 aa)
Pea15Astrocytic phosphoprotein PEA-15. (130 aa)
CgPICR_019210Melatonin receptor type 1B. (112 aa)
I79_006005Melatonin receptor type 1B; Belongs to the G-protein coupled receptor 1 family. (240 aa)
Gpr35G-protein coupled receptor 35; Belongs to the G-protein coupled receptor 1 family. (304 aa)
Rgs2Regulator of G-protein signaling 2. (207 aa)
I79_005001Voltage-dependent anion-selective channel protein 1. (71 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CrbnProtein cereblon. (445 aa)
Drd2D(2) dopamine receptor. (274 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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