STRINGSTRING
Psen1 Psen1 Gja1 Gja1 I79_025625 I79_025625 Hhex Hhex I79_024810 I79_024810 I79_024483 I79_024483 I79_024087 I79_024087 Folr1 Folr1 Pitx2 Pitx2 I79_021692 I79_021692 Sox18 Sox18 C2cd3 C2cd3 I79_019340 I79_019340 I79_019149 I79_019149 Tbx20 Tbx20 Tbx6 Tbx6 I79_018218 I79_018218 Kdm2a Kdm2a I79_018181 I79_018181 H671_4g11668 H671_4g11668 Traf3ip1 Traf3ip1 Ift52 Ift52 Tmem145 Tmem145 Cluap1 Cluap1 I79_016697 I79_016697 I79_016660 I79_016660 Hif1a Hif1a Srf Srf Sufu Sufu Npm3 Npm3 Tmed2 Tmed2 I79_015503 I79_015503 Foxh1 Foxh1 Ihh Ihh I79_015223 I79_015223 Ift122 Ift122 I79_014722 I79_014722 I79_014721 I79_014721 Tead1 Tead1 I79_014629 I79_014629 Asb2 Asb2 Ccdc39 Ccdc39 Ccdc40 Ccdc40 Aplnr Aplnr Invs Invs Notch2 Notch2 Dll1 Dll1 I79_012425 I79_012425 I79_012424 I79_012424 I79_012231 I79_012231 Plxna4 Plxna4 Ccdc103 Ccdc103 Cdc42 Cdc42 Acvr1 Acvr1 I79_010136 I79_010136 I79_009702 I79_009702 I79_008481 I79_008481 Lrp6 Lrp6 I79_007641 I79_007641 Mef2c Mef2c I79_007135 I79_007135 Ednra Ednra Ctnnb1 Ctnnb1 Pcnt Pcnt Smad3 Smad3 I79_006673 I79_006673 Vangl2 Vangl2 Ift57 Ift57 I79_006225 I79_006225 Nodal Nodal I79_005961 I79_005961 Med1 Med1 Gja5 Gja5 Kif3a Kif3a Edn1 Edn1 Nphp3 Nphp3 Smo Smo Stil Stil Arl13b Arl13b Ift172 Ift172 Ahi1 Ahi1 I79_001871 I79_001871 Tgfbr2 Tgfbr2 Nkx2-6 Nkx2-6 I79_001484 I79_001484 Wnt5a Wnt5a Tbx3 Tbx3 I79_000275 I79_000275
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
Gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
I79_025625Polycystin-2. (318 aa)
HhexHematopoietically-expressed homeobox protein Hhex. (98 aa)
I79_024810Cryptic protein. (69 aa)
I79_024483Polycystin-2. (192 aa)
I79_024087Transcriptional enhancer factor TEF-4. (198 aa)
Folr1Folate receptor alpha. (257 aa)
Pitx2Homeobox protein. (322 aa)
I79_021692Transcription factor LBX1. (90 aa)
Sox18Transcription factor SOX-18. (377 aa)
C2cd3C2 domain-containing protein 3. (2233 aa)
I79_019340Suppressor of fused-like. (144 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Tbx20T-box transcription factor TBX20. (445 aa)
Tbx6T-box transcription factor TBX6-like isoform 1. (436 aa)
I79_018218Plexin-A4. (498 aa)
Kdm2aLysine-specific demethylase 2A. (977 aa)
I79_018181Lysine-specific demethylase 2A. (122 aa)
H671_4g11668Chordin. (842 aa)
Traf3ip1TRAF3-interacting protein 1. (88 aa)
Ift52Intraflagellar transport protein 52-like. (425 aa)
Tmem145Multiple epidermal growth factor-like domains 8. (2639 aa)
Cluap1Clusterin-associated protein 1. (238 aa)
I79_016697Clusterin-associated protein 1. (172 aa)
I79_016660Transcriptional enhancer factor TEF-4. (375 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
SrfSerum response factor. (361 aa)
SufuSuppressor of fused-like. (266 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Tmed2Transmembrane emp24 domain-containing protein 2. (116 aa)
I79_015503Transcription factor HES-1. (92 aa)
Foxh1Forkhead box protein H1. (367 aa)
IhhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (918 aa)
I79_015223Neurogenic locus notch-like protein 2. (248 aa)
Ift122Intraflagellar transport protein 122-like. (292 aa)
I79_014722Protein MICAL-2. (1070 aa)
I79_014721BMERB domain-containing protein. (660 aa)
Tead1Transcriptional enhancer factor TEF-1. (432 aa)
I79_014629Sodium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (369 aa)
Asb2Ankyrin repeat and SOCS box protein 2. (639 aa)
Ccdc39Coiled-coil domain-containing protein 39. (51 aa)
Ccdc40Coiled-coil domain-containing protein 40. (75 aa)
AplnrApelin receptor; Belongs to the G-protein coupled receptor 1 family. (377 aa)
InvsInversin. (1054 aa)
Notch2Neurogenic locus notch-like protein 2. (1521 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
I79_012425Ryanodine receptor 2. (2233 aa)
I79_012424Ryanodine receptor 2. (2535 aa)
I79_012231Plexin-A4. (332 aa)
Plxna4Plexin-A4. (1078 aa)
Ccdc103Coiled-coil domain-containing protein 103. (237 aa)
Cdc42Cell division control protein 42-like. (191 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
I79_010136Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (230 aa)
I79_009702E3 ubiquitin-protein ligase MIB1. (739 aa)
I79_008481Intraflagellar transport protein 57-like. (162 aa)
Lrp6Low-density lipoprotein receptor-related protein 6. (565 aa)
I79_007641Low-density lipoprotein receptor-related protein 6. (543 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
I79_007135Homeobox protein Nkx-2.5. (223 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Ctnnb1Catenin beta-1. (781 aa)
PcntPericentrin. (3034 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
I79_006673Nck-associated protein 1. (951 aa)
Vangl2Vang-like protein. (521 aa)
Ift57Intraflagellar transport protein 57-like. (296 aa)
I79_006225Sonic hedgehog protein. (226 aa)
NodalNodal. (309 aa)
I79_005961Zinc finger protein ZIC 3. (89 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
Gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
Kif3aKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (646 aa)
Edn1Endothelin-1. (202 aa)
Nphp3Nephrocystin-3. (542 aa)
SmoSmoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
StilUncharacterized protein. (1249 aa)
Arl13bADP-ribosylation factor-like protein 13B. (422 aa)
Ift172Intraflagellar transport protein 172-like. (1340 aa)
Ahi1Jouberin. (988 aa)
I79_001871Transcription factor Ovo-like 2. (213 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Nkx2-6Homeobox protein Nkx-2.6. (273 aa)
I79_00148465 kDa Yes-associated protein. (257 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Tbx3T-box transcription factor TBX3. (709 aa)
I79_000275Dynein assembly factor 1, axonemal. (437 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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