node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arid5a | Smarcb1 | G3H1S0 | G3HY10 | AT-rich interactive domain-containing protein 5A. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1. | 0.580 |
Arrb1 | Mapk3 | G3IIY3 | G3I4H1 | Beta-arrestin-1. | Mitogen-activated protein kinase. | 0.964 |
Brca1 | I79_005608 | G3HM05 | G3H5M3 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Bromodomain-containing protein 7. | 0.505 |
Brca1 | I79_006232 | G3HM05 | G3H7A2 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | PAX-interacting protein 1. | 0.670 |
Brca1 | I79_010901 | G3HM05 | G3HJQ2 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.427 |
Brca1 | Paxip1 | G3HM05 | G3IP65 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | PAX-interacting protein 1. | 0.670 |
Foxp3 | Gata3 | G3HNB1 | G3GR59 | Forkhead box protein P3. | Trans-acting T-cell-specific transcription factor GATA-3. | 0.814 |
Foxp3 | Tgfb1 | G3HNB1 | G3IA12 | Forkhead box protein P3. | Transforming growth factor beta-1. | 0.581 |
Gata3 | Foxp3 | G3GR59 | G3HNB1 | Trans-acting T-cell-specific transcription factor GATA-3. | Forkhead box protein P3. | 0.814 |
Gata3 | Isl1 | G3GR59 | G3H207 | Trans-acting T-cell-specific transcription factor GATA-3. | Insulin gene enhancer protein ISL-1. | 0.504 |
Gata3 | Kat2a | G3GR59 | G3HLW3 | Trans-acting T-cell-specific transcription factor GATA-3. | Histone acetyltransferase KAT2A. | 0.494 |
I79_005238 | I79_010901 | G3H4N3 | G3HJQ2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.522 |
I79_005238 | I79_016664 | G3H4N3 | G3HZZ9 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | PIH1 domain-containing protein 1. | 0.947 |
I79_005238 | Kat2a | G3H4N3 | G3HLW3 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | Histone acetyltransferase KAT2A. | 0.428 |
I79_005608 | Brca1 | G3H5M3 | G3HM05 | Bromodomain-containing protein 7. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.505 |
I79_005608 | Smarcb1 | G3H5M3 | G3HY10 | Bromodomain-containing protein 7. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1. | 0.941 |
I79_006232 | Brca1 | G3H7A2 | G3HM05 | PAX-interacting protein 1. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.670 |
I79_006232 | Paxip1 | G3H7A2 | G3IP65 | PAX-interacting protein 1. | PAX-interacting protein 1. | 0.933 |
I79_010901 | Brca1 | G3HJQ2 | G3HM05 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.427 |
I79_010901 | I79_005238 | G3HJQ2 | G3H4N3 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.522 |