(37 nodes) Non-canonical Wnt signaling pathway network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_022271	Ras-related C3 botulinum toxin substrate 2. (178 aa)
	Celsr1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (1009 aa)
	I79_023738	Cadherin EGF LAG seven-pass G-type receptor 1. (979 aa)
	I79_025697	Intraflagellar transport protein 80-like. (113 aa)
	Wnt9b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
	Wnt7a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (282 aa)
	Wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
	Rac1	Ras-related C3 botulinum toxin substrate 1. (148 aa)
	Phf23	Segment polarity protein dishevelled-like DVL-2. (697 aa)
	Fzd7	Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (438 aa)
	Sfrp5	Secreted frizzled-related protein 5. (247 aa)
	Fzd3	Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	I79_005573	Secreted frizzled-related protein 2. (268 aa)
	Vangl2	Vang-like protein. (521 aa)
	I79_008405	Tyrosine-protein kinase RYK. (141 aa)
	I79_009708	Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (332 aa)
	Sfrp1	Secreted frizzled-related protein 1. (104 aa)
	Wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
	I79_011268	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3109 aa)
	Fzd1	Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (514 aa)
	Fzd2	Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (522 aa)
	Grhl3	Grainyhead-like protein 3-like. (596 aa)
	Myoc	Myocilin. (502 aa)
	Wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	I79_016051	Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (777 aa)
	I79_016223	Tyrosine-protein kinase-like 7. (98 aa)
	Fzd10	Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (488 aa)
	Dvl3	Segment polarity protein dishevelled-like DVL-3. (503 aa)
	Ccdc88c	Protein Daple. (225 aa)
	I79_018043	Frizzled-6. (109 aa)
	Dvl1	Putative segment polarity protein dishevelledVL-1-like protein. (695 aa)
	I79_018312	Tyrosine-protein kinase RYK. (163 aa)
	I79_019493	Mediator of RNA polymerase II transcription subunit 12. (251 aa)
	Med12	Mediator of RNA polymerase II transcription subunit 12. (1703 aa)
	Ift80	Intraflagellar transport protein 80-like. (366 aa)
	Wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	Fzd4	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ccdc88c	Dvl1	G3I398	G3I423	Protein Daple.	Putative segment polarity protein dishevelledVL-1-like protein.	0.712
Ccdc88c	Phf23	G3I398	G3GYA1	Protein Daple.	Segment polarity protein dishevelled-like DVL-2.	0.412
Celsr1	Fzd1	G3IF66	G3HL91	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.484
Celsr1	Fzd3	G3IF66	G3H0J5	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family.	0.655
Celsr1	Grhl3	G3IF66	G3HMT8	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	Grainyhead-like protein 3-like.	0.650
Celsr1	I79_018043	G3IF66	G3I3N3	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	Frizzled-6.	0.556
Celsr1	I79_023738	G3IF66	G3IIR4	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	Cadherin EGF LAG seven-pass G-type receptor 1.	0.901
Celsr1	Sfrp1	G3IF66	G3HHI7	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	Secreted frizzled-related protein 1.	0.484
Celsr1	Vangl2	G3IF66	G3H7X7	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	Vang-like protein.	0.760
Dvl1	Ccdc88c	G3I423	G3I398	Putative segment polarity protein dishevelledVL-1-like protein.	Protein Daple.	0.712
Dvl1	Dvl3	G3I423	G3I320	Putative segment polarity protein dishevelledVL-1-like protein.	Segment polarity protein dishevelled-like DVL-3.	0.966
Dvl1	Fzd1	G3I423	G3HL91	Putative segment polarity protein dishevelledVL-1-like protein.	Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.972
Dvl1	Fzd10	G3I423	G3I1I6	Putative segment polarity protein dishevelledVL-1-like protein.	Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family.	0.951
Dvl1	Fzd2	G3I423	G3HLK8	Putative segment polarity protein dishevelledVL-1-like protein.	Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family.	0.967
Dvl1	Fzd3	G3I423	G3H0J5	Putative segment polarity protein dishevelledVL-1-like protein.	Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family.	0.980
Dvl1	Fzd4	G3I423	G3IEM3	Putative segment polarity protein dishevelledVL-1-like protein.	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.975
Dvl1	Fzd7	G3I423	G3GYW8	Putative segment polarity protein dishevelledVL-1-like protein.	Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family.	0.983
Dvl1	I79_005573	G3I423	G3H5J1	Putative segment polarity protein dishevelledVL-1-like protein.	Secreted frizzled-related protein 2.	0.507
Dvl1	I79_008405	G3I423	G3HD31	Putative segment polarity protein dishevelledVL-1-like protein.	Tyrosine-protein kinase RYK.	0.448
Dvl1	I79_016051	G3I423	G3HYC6	Putative segment polarity protein dishevelledVL-1-like protein.	Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.411