(32 nodes) Aorta morphogenesis network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Nprl3	UPF0171 protein C16orf35-like. (569 aa)
	I79_019149	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
	Efemp2	EGF-containing fibulin-like extracellular matrix protein 2. (375 aa)
	Srf	Serum response factor. (361 aa)
	Npm3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
	Col3a1	Collagen alpha-1(III) chain. (1051 aa)
	Six1	Homeobox protein SIX1. (284 aa)
	Dll4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (578 aa)
	Rbpj	Recombining binding protein suppressor of hairless-like protein. (486 aa)
	I79_012814	Chromodomain-helicase-DNA-binding protein 7. (100 aa)
	I79_012815	Chromodomain-helicase-DNA-binding protein 7. (150 aa)
	Chd7	Chromodomain-helicase-DNA-binding protein 7. (615 aa)
	I79_012894	Transcription factor AP-2 beta. (287 aa)
	I79_013660	Beta-type platelet-derived growth factor receptor. (454 aa)
	Pdgfrb	Beta-type platelet-derived growth factor receptor. (528 aa)
	I79_015033	Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
	Lrp1	Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
	Foxh1	Forkhead box protein H1. (367 aa)
	I79_000092	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	Prox1	Prospero homeobox protein 1. (738 aa)
	I79_000337	A disintegrin and metalloproteinase with thrombospondin motifs 9. (1068 aa)
	Adamts9	A disintegrin and metalloproteinase with thrombospondin motifs 9. (489 aa)
	Jag1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
	I79_000661	Myosin light chain kinase, smooth muscle. (1766 aa)
	Tbx2	T-box transcription factor TBX2. (234 aa)
	Acvrl1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (776 aa)
	I79_009030	T-box transcription factor TBX1. (293 aa)
	Kat6a	Histone acetyltransferase MYST3. (200 aa)
	Fkbp10	Peptidylprolyl isomerase. (581 aa)
	I79_012727	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa)
	I79_015503	Transcription factor HES-1. (92 aa)
	Hey2	Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acvrl1	I79_000092	G3IC00	G3GRE7	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.576
Adamts9	I79_000337	G3GS31	G3GS30	A disintegrin and metalloproteinase with thrombospondin motifs 9.	A disintegrin and metalloproteinase with thrombospondin motifs 9.	0.839
Chd7	I79_012814	G3HPU6	G3HPU4	Chromodomain-helicase-DNA-binding protein 7.	Chromodomain-helicase-DNA-binding protein 7.	0.886
Chd7	I79_012815	G3HPU6	G3HPU5	Chromodomain-helicase-DNA-binding protein 7.	Chromodomain-helicase-DNA-binding protein 7.	0.845
Col3a1	Efemp2	G3IM20	G3I2G7	Collagen alpha-1(III) chain.	EGF-containing fibulin-like extracellular matrix protein 2.	0.663
Dll4	Hey2	G3ICK3	G3IB43	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 2.	0.712
Dll4	I79_015033	G3ICK3	G3HVP3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 1.	0.535
Dll4	I79_015503	G3ICK3	G3HWY8	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Transcription factor HES-1.	0.596
Dll4	Jag1	G3ICK3	G3GSA7	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.503
Dll4	Rbpj	G3ICK3	G3ICG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombining binding protein suppressor of hairless-like protein.	0.800
Efemp2	Col3a1	G3I2G7	G3IM20	EGF-containing fibulin-like extracellular matrix protein 2.	Collagen alpha-1(III) chain.	0.663
Efemp2	Fkbp10	G3I2G7	G3HLV1	EGF-containing fibulin-like extracellular matrix protein 2.	Peptidylprolyl isomerase.	0.761
Fkbp10	Efemp2	G3HLV1	G3I2G7	Peptidylprolyl isomerase.	EGF-containing fibulin-like extracellular matrix protein 2.	0.761
Hey2	Dll4	G3IB43	G3ICK3	Hairy/enhancer-of-split related with YRPW motif protein 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.712
Hey2	I79_015033	G3IB43	G3HVP3	Hairy/enhancer-of-split related with YRPW motif protein 2.	Hairy/enhancer-of-split related with YRPW motif protein 1.	0.668
Hey2	Jag1	G3IB43	G3GSA7	Hairy/enhancer-of-split related with YRPW motif protein 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.785
Hey2	Rbpj	G3IB43	G3ICG1	Hairy/enhancer-of-split related with YRPW motif protein 2.	Recombining binding protein suppressor of hairless-like protein.	0.642
I79_000092	Acvrl1	G3GRE7	G3IC00	Transforming growth factor beta; Belongs to the TGF-beta family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.576
I79_000337	Adamts9	G3GS30	G3GS31	A disintegrin and metalloproteinase with thrombospondin motifs 9.	A disintegrin and metalloproteinase with thrombospondin motifs 9.	0.839
I79_000661	Kat6a	G3GSP4	G3HHI0	Myosin light chain kinase, smooth muscle.	Histone acetyltransferase MYST3.	0.459