(43 nodes) Endodermal cell differentiation network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_019499	Collagen alpha-2(IV) chain. (324 aa)
	Col8a1	Collagen alpha-1(VIII) chain. (745 aa)
	Itga5	Integrin alpha-5; Belongs to the integrin alpha chain family. (729 aa)
	Inhba	Inhibin beta A chain-like protein. (424 aa)
	Nr0b1	Nuclear receptor subfamily 0 group B member 1. (470 aa)
	Ctr9	RNA polymerase-associated protein CTR9-like. (1171 aa)
	I79_016797	Dual specificity mitogen-activated protein kinase kinase 1. (129 aa)
	Col4a2	Collagen alpha-2(IV) chain. (350 aa)
	Fn1	Fibronectin. (2486 aa)
	Lamb1	Laminin subunit beta-1. (1617 aa)
	Pou5f1	POU domain protein. (358 aa)
	I79_013395	Matrix metalloproteinase-14. (539 aa)
	I79_014076	Laminin subunit alpha-3. (441 aa)
	I79_014650	Parafibromin. (260 aa)
	Cdc73	Parafibromin. (164 aa)
	I79_014847	Homeobox protein MIXL1. (125 aa)
	Setd2	Histone-lysine N-methyltransferase SETD2. (2412 aa)
	Sox2	Transcription factor SOX-2. (273 aa)
	Paf1	RNA polymerase II-associated factor 1-like. (537 aa)
	Itgav	Integrin alpha-V; Belongs to the integrin alpha chain family. (944 aa)
	I79_009930	Collagen alpha-1(XII) chain. (2456 aa)
	I79_008633	Integrin alpha-4; Belongs to the integrin alpha chain family. (441 aa)
	I79_007326	POU domain, class 5, transcription factor 1. (221 aa)
	Ctnnb1	Catenin beta-1. (781 aa)
	I79_006834	Collagen alpha-1(VI) chain. (822 aa)
	Mmp9	Matrix metalloproteinase-9. (710 aa)
	I79_006342	Heat shock factor-binding protein 1. (90 aa)
	Nodal	Nodal. (309 aa)
	Lamb3	Laminin subunit beta-3. (1166 aa)
	Rtf1	RNA polymerase-associated protein RTF1-like. (585 aa)
	Mmp2	72 kDa type IV collagenase. (662 aa)
	I79_002659	High mobility group protein HMGI-C. (103 aa)
	Eomes	Eomesodermin-like. (446 aa)
	Vtn	Vitronectin. (876 aa)
	CgPICR_012052	Growth factor receptor-bound protein 2. (217 aa)
	Itgb5	Integrin beta; Belongs to the integrin beta chain family. (771 aa)
	CgPICR_015914	Heat shock factor-binding protein 1. (128 aa)
	Leo1	RNA polymerase-associated protein LEO1. (760 aa)
	I79_025798	Vitronectin. (230 aa)
	Hnf1b	Hepatocyte nuclear factor 1-beta. (593 aa)
	I79_018432	Homeobox protein NANOG. (490 aa)
	Mmp15	Matrix metalloproteinase-15. (555 aa)
	Map2k1	Dual specificity mitogen-activated protein kinase kinase 1. (101 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdc73	Ctnnb1	G3HUN9	G3H996	Parafibromin.	Catenin beta-1.	0.725
Cdc73	Ctr9	G3HUN9	G3HYL1	Parafibromin.	RNA polymerase-associated protein CTR9-like.	0.982
Cdc73	I79_014650	G3HUN9	G3HUN7	Parafibromin.	Parafibromin.	0.950
Cdc73	Leo1	G3HUN9	G3GRH6	Parafibromin.	RNA polymerase-associated protein LEO1.	0.999
Cdc73	Paf1	G3HUN9	G3HJD2	Parafibromin.	RNA polymerase II-associated factor 1-like.	0.981
Cdc73	Rtf1	G3HUN9	G3H102	Parafibromin.	RNA polymerase-associated protein RTF1-like.	0.948
Cdc73	Setd2	G3HUN9	G3HKR8	Parafibromin.	Histone-lysine N-methyltransferase SETD2.	0.468
CgPICR_012052	Fn1	G3GTE4	G3I1V3	Growth factor receptor-bound protein 2.	Fibronectin.	0.436
CgPICR_012052	Itga5	G3GTE4	G3I6C1	Growth factor receptor-bound protein 2.	Integrin alpha-5; Belongs to the integrin alpha chain family.	0.440
CgPICR_012052	Itgav	G3GTE4	G3HHR9	Growth factor receptor-bound protein 2.	Integrin alpha-V; Belongs to the integrin alpha chain family.	0.414
CgPICR_012052	Itgb5	G3GTE4	G3GSN8	Growth factor receptor-bound protein 2.	Integrin beta; Belongs to the integrin beta chain family.	0.524
Col4a2	Col8a1	G3I1T5	G3HMN0	Collagen alpha-2(IV) chain.	Collagen alpha-1(VIII) chain.	0.915
Col4a2	I79_009930	G3I1T5	G3HH34	Collagen alpha-2(IV) chain.	Collagen alpha-1(XII) chain.	0.647
Col4a2	Itga5	G3I1T5	G3I6C1	Collagen alpha-2(IV) chain.	Integrin alpha-5; Belongs to the integrin alpha chain family.	0.743
Col4a2	Itgav	G3I1T5	G3HHR9	Collagen alpha-2(IV) chain.	Integrin alpha-V; Belongs to the integrin alpha chain family.	0.934
Col4a2	Itgb5	G3I1T5	G3GSN8	Collagen alpha-2(IV) chain.	Integrin beta; Belongs to the integrin beta chain family.	0.764
Col4a2	Lamb1	G3I1T5	G3I278	Collagen alpha-2(IV) chain.	Laminin subunit beta-1.	0.464
Col8a1	Col4a2	G3HMN0	G3I1T5	Collagen alpha-1(VIII) chain.	Collagen alpha-2(IV) chain.	0.915
Col8a1	I79_006834	G3HMN0	G3H8Y5	Collagen alpha-1(VIII) chain.	Collagen alpha-1(VI) chain.	0.406
Col8a1	I79_009930	G3HMN0	G3HH34	Collagen alpha-1(VIII) chain.	Collagen alpha-1(XII) chain.	0.421