(33 nodes) Regulation of fibroblast growth factor receptor signaling pathway network (Cricetulus griseus)

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second shell of interactors

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a 3D structure is known or predicted

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Your Input:
	I79_017780	Extracellular sulfatase Sulf-1. (787 aa)
	I79_018849	Serine/threonine-protein kinase D2. (513 aa)
	Sulf2	Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (875 aa)
	Shisa2	Protein shisa-2-like. (220 aa)
	Gpc1	Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (781 aa)
	H671_3g8910	Fibroblast growth factor-binding protein 3. (71 aa)
	Fuz	Protein fuzzy-like. (365 aa)
	I79_019293	Protein fuzzy-like. (60 aa)
	Prdm14	PR domain zinc finger protein 14. (564 aa)
	I79_020783	Transcription factor 7-like 2. (451 aa)
	Tcf7l2	Transcription factor 7-like 1. (73 aa)
	Fgfbp1	Fibroblast growth factor-binding protein 1. (248 aa)
	Ngfr	Tumor necrosis factor receptor superfamily member 16. (429 aa)
	Wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
	Thbs1	Thrombospondin-1. (533 aa)
	Spry4	Protein sprouty-like 4. (100 aa)
	Nptn	Neuroplastin. (219 aa)
	Ctnnb1	Catenin beta-1. (781 aa)
	I79_008974	Basigin. (116 aa)
	Runx2	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (365 aa)
	Dstyk	Dual serine/threonine and tyrosine protein kinase. (866 aa)
	Hhip	Hedgehog-interacting protein. (671 aa)
	Pdgfb	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
	Ofd1	Oral-facial-digital syndrome 1 protein-like. (957 aa)
	H671_3g10913	Protein sprouty-like 4. (82 aa)
	Fam20c	Dentin matrix protein 4. (776 aa)
	Nog	Noggin. (117 aa)
	Creb3l1	Cyclic AMP-responsive element-binding protein 3-like protein 1. (475 aa)
	Wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
	Gata3	Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
	Spry1	Protein sprouty-like 1. (313 aa)
	Nrxn1	Neurexin-1-alpha. (849 aa)
	Smoc2	SPARC-related modular calcium-binding protein 2. (457 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ctnnb1	I79_020783	G3H996	G3IAZ7	Catenin beta-1.	Transcription factor 7-like 2.	0.956
Ctnnb1	Runx2	G3H996	G3HC75	Catenin beta-1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.617
Ctnnb1	Tcf7l2	G3H996	G3IIN4	Catenin beta-1.	Transcription factor 7-like 1.	0.995
Ctnnb1	Wnt4	G3H996	G3HIM9	Catenin beta-1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.679
Ctnnb1	Wnt5a	G3H996	G3GUT6	Catenin beta-1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.628
Gata3	Runx2	G3GR59	G3HC75	Trans-acting T-cell-specific transcription factor GATA-3.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.623
Gpc1	Sulf2	G3H4T5	G3H8T0	Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family.	0.526
H671_3g10913	Spry1	G3HWB5	G3HTL0	Protein sprouty-like 4.	Protein sprouty-like 1.	0.482
Hhip	Wnt4	G3H9G2	G3HIM9	Hedgehog-interacting protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.414
I79_008974	Nptn	G3HEJ0	G3HEJ1	Basigin.	Neuroplastin.	0.608
I79_020783	Ctnnb1	G3IAZ7	G3H996	Transcription factor 7-like 2.	Catenin beta-1.	0.956
I79_020783	Runx2	G3IAZ7	G3HC75	Transcription factor 7-like 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.430
Ngfr	Pdgfb	G3HJP7	G3I2J0	Tumor necrosis factor receptor superfamily member 16.	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	0.703
Nog	Runx2	G3H1C7	G3HC75	Noggin.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.453
Nptn	I79_008974	G3HEJ1	G3HEJ0	Neuroplastin.	Basigin.	0.608
Pdgfb	Ngfr	G3I2J0	G3HJP7	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	Tumor necrosis factor receptor superfamily member 16.	0.703
Pdgfb	Thbs1	G3I2J0	G3HHV4	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	Thrombospondin-1.	0.577
Runx2	Ctnnb1	G3HC75	G3H996	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Catenin beta-1.	0.617
Runx2	Gata3	G3HC75	G3GR59	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Trans-acting T-cell-specific transcription factor GATA-3.	0.623
Runx2	I79_020783	G3HC75	G3IAZ7	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Transcription factor 7-like 2.	0.430