STRINGSTRING
I79_024066 I79_024066 Cd34 Cd34 Csf1 Csf1 I79_019149 I79_019149 Pax9 Pax9 Dicer1 Dicer1 Tgfb1 Tgfb1 Msx1 Msx1 Edn1 Edn1 Apcdd1 Apcdd1 Sp6 Sp6 I79_006225 I79_006225 I79_006254 I79_006254 I79_006693 I79_006693 Ednra Ednra I79_007336 I79_007336 Runx2 Runx2 Apc Apc Ngfr Ngfr I79_015320 I79_015320 Npm3 Npm3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_024066Doublesex-and mab-3-related transcription factor 3. (415 aa)
Cd34Hematopoietic progenitor cell antigen CD34. (383 aa)
Csf1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (552 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Pax9Paired box protein Pax-9. (316 aa)
Dicer1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Msx1Homeobox protein MSX-1. (261 aa)
Edn1Endothelin-1. (202 aa)
Apcdd1Protein APCDD1. (459 aa)
Sp6Transcription factor Sp6. (376 aa)
I79_006225Sonic hedgehog protein. (226 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006693Intraflagellar transport protein 88-like. (533 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
I79_007336Tumor necrosis factor receptor superfamily member 11B. (323 aa)
Runx2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (365 aa)
ApcAdenomatous polyposis coli protein. (2488 aa)
NgfrTumor necrosis factor receptor superfamily member 16. (429 aa)
I79_015320Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (477 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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