STRINGSTRING
Mdk Mdk I79_011711 I79_011711 I79_011712 I79_011712 H671_3g8701 H671_3g8701 Kiss1 Kiss1 I79_013032 I79_013032 Mmp19 Mmp19 I79_013999 I79_013999 Inhba Inhba I79_015056 I79_015056 I79_015509 I79_015509 Gabrb1 Gabrb1 Ncor2 Ncor2 Gpr149 Gpr149 Adamts1 Adamts1 Anxa1 Anxa1 Npy5r Npy5r Nr5a1 Nr5a1 Hnrnpul1 Hnrnpul1 Ereg Ereg Tnfaip6 Tnfaip6 I79_022080 I79_022080 Cckbr Cckbr Fzd4 Fzd4 Arrb1 Arrb1 Mstn Mstn Pdgfra Pdgfra Serpinf1 Serpinf1 I79_024593 I79_024593 I79_025170 I79_025170 I79_025221 I79_025221 I79_025441 I79_025441 Has2 Has2 I79_025944 I79_025944 I79_026091 I79_026091 FSHB FSHB Lrrc3 Lrrc3 I79_002785 I79_002785 Src Src Foxo3 Foxo3 Agt Agt Pla2g4a Pla2g4a I79_001957 I79_001957 I79_001955 I79_001955 I79_001487 I79_001487 I79_006547 I79_006547 Oprm1 Oprm1 Znf830 Znf830 I79_006036 I79_006036 FSHR FSHR LHCGR LHCGR I79_005358 I79_005358 Nrip1 Nrip1 Pcna Pcna Ptx3 Ptx3 Oxtr Oxtr Tyro3 Tyro3 Casp2 Casp2 Igf1r Igf1r Adrm1 Adrm1 Egr1 Egr1 Adnp Adnp I79_008941 I79_008941 I79_008250 I79_008250 I79_007693 I79_007693 Sirt1 Sirt1 I79_007340 I79_007340 Ptn Ptn Mmp2 Mmp2 Scaper Scaper Lep Lep
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MdkMidkine. (160 aa)
I79_011711Signal transducer and activator of transcription 5B. (274 aa)
I79_011712Signal transducer and activator of transcription. (793 aa)
H671_3g8701Growth arrest-specific protein 2. (314 aa)
Kiss1Metastasis-suppressor KiSS-1. (262 aa)
I79_013032Peptidyl-glycine alpha-amidating monooxygenase B. (851 aa)
Mmp19Matrix metalloproteinase-19. (525 aa)
I79_013999Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (328 aa)
InhbaInhibin beta A chain-like protein. (424 aa)
I79_015056Neuronal acetylcholine receptor subunit alpha-7. (412 aa)
I79_015509Gamma-aminobutyric acid receptor subunit beta-1. (83 aa)
Gabrb1Gamma-aminobutyric acid receptor subunit beta-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (343 aa)
Ncor2Nuclear receptor corepressor 2. (2530 aa)
Gpr149Putative G-protein coupled receptor 149. (541 aa)
Adamts1A disintegrin and metalloproteinase with thrombospondin motifs 1. (705 aa)
Anxa1Annexin. (346 aa)
Npy5rNeuropeptide Y receptor type 5-like protein. (466 aa)
Nr5a1Steroidogenic factor 1. (462 aa)
Hnrnpul1Heterogeneous nuclear ribonucleoprotein U-like protein 1. (1566 aa)
EregProepiregulin. (162 aa)
Tnfaip6Tumor necrosis factor-inducible gene 6 protein. (275 aa)
I79_022080Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (402 aa)
CckbrGastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family. (418 aa)
Fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
Arrb1Beta-arrestin-1. (422 aa)
MstnGrowth/differentiation factor 8. (295 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
Serpinf1Pigment epithelium-derived factor; Belongs to the serpin family. (94 aa)
I79_024593Uncharacterized protein. (194 aa)
I79_025170Slit-like 2 protein. (345 aa)
I79_025221Alpha-fetoprotein. (455 aa)
I79_025441Receptor-type tyrosine-protein phosphatase-like N. (761 aa)
Has2Hyaluronan synthase 2. (337 aa)
I79_025944Hyaluronan synthase 2. (151 aa)
I79_026091Pigment epithelium-derived factor; Belongs to the serpin family. (58 aa)
FSHBFollicle stimulating hormone beta-subunit protein. (129 aa)
Lrrc3Transient receptor potential cation channel subfamily M member 2. (1604 aa)
I79_002785Beta-arrestin-2. (65 aa)
SrcTyrosine-protein kinase. (536 aa)
Foxo3Forkhead box protein O3. (672 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Pla2g4aPhospholipase A2. (749 aa)
I79_001957Slit-like 3 protein. (751 aa)
I79_001955Slit-like 3 protein. (566 aa)
I79_001487Progesterone receptor. (741 aa)
I79_006547Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (311 aa)
Oprm1Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (394 aa)
Znf830Zinc finger protein 830. (369 aa)
I79_006036Sphingosine-1-phosphate lyase 1. (568 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (487 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (688 aa)
I79_005358Estrogen receptor beta. (58 aa)
Nrip1Nuclear receptor-interacting protein 1. (1172 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Ptx3Pentraxin-related protein PTX3. (381 aa)
OxtrOxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (353 aa)
Tyro3Tyrosine-protein kinase receptor TYRO3. (816 aa)
Casp2Caspase-2; Belongs to the peptidase C14A family. (421 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
Adrm1Proteasomal ubiquitin receptor ADRM1. (407 aa)
Egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (421 aa)
AdnpActivity-dependent neuroprotector homeobox protein. (1102 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
I79_008250Endothelin-2. (137 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_007340Ectonucleotide pyrophosphatase/phosphodiesterase family member 2. (592 aa)
PtnPleiotrophin. (168 aa)
Mmp272 kDa type IV collagenase. (662 aa)
ScaperS phase cyclin A-associated protein in the endoplasmic reticulum. (1395 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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