(74 nodes) Embryonic digit morphogenesis network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Zbtb16	Zinc finger and BTB domain-containing protein 16. (423 aa)
	Intu	PDZ domain-containing protein 6. (938 aa)
	Chst11	Carbohydrate sulfotransferase. (352 aa)
	Smad4	Mothers against decapentaplegic-like 4. (259 aa)
	I79_014806	Homeobox protein Hox-C11. (229 aa)
	Gli3	Zinc finger protein GLI3. (1582 aa)
	Ift122	Intraflagellar transport protein 122-like. (292 aa)
	Frem2	FRAS1-related extracellular matrix protein 2. (3104 aa)
	Ihh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (918 aa)
	Alx4	Homeobox protein aristaless-like 4. (237 aa)
	Rab23	Ras-related protein Rab-23. (236 aa)
	I79_016051	Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (777 aa)
	I79_016358	Feline leukemia virus subgroup C receptor-related protein 1. (100 aa)
	Flvcr1	Feline leukemia virus subgroup C receptor-related protein 1. (222 aa)
	Ift52	Intraflagellar transport protein 52-like. (425 aa)
	I79_017450	Zinc finger and BTB domain-containing protein 16. (236 aa)
	Traf3ip1	TRAF3-interacting protein 1. (88 aa)
	I79_018043	Frizzled-6. (109 aa)
	Tmem231	UPF0513 transmembrane protein. (315 aa)
	Fbxw4	F-box/WD repeat-containing protein 4. (292 aa)
	Lrp5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1608 aa)
	Fuz	Protein fuzzy-like. (365 aa)
	I79_019293	Protein fuzzy-like. (60 aa)
	Lmbr1	Limb region 1 protein. (165 aa)
	C2cd3	C2 domain-containing protein 3. (2233 aa)
	I79_024202	Sal-like protein 1. (825 aa)
	I79_024203	Sal-like protein 1. (121 aa)
	Gja1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
	Wnt7a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (282 aa)
	I79_000801	Histone deacetylase 1. (92 aa)
	Tbx3	T-box transcription factor TBX3. (709 aa)
	I79_001275	Uncharacterized protein. (119 aa)
	Map3k20	Mitogen-activated protein kinase kinase kinase MLT. (445 aa)
	Tulp3	Tubby-like protein; Belongs to the TUB family. (414 aa)
	Wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
	Gna12	Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
	B9d1	B9 domain-containing protein 1. (84 aa)
	Msx1	Homeobox protein MSX-1. (261 aa)
	I79_003468	Bcl-2-like protein 11. (141 aa)
	I79_003784	Tau-tubulin kinase 2. (1175 aa)
	Gli2	Zinc finger protein GLI2. (1547 aa)
	Msx2	Homeobox protein MSX-2. (267 aa)
	Nog	Noggin. (117 aa)
	Hoxd12	Homeobox protein Hox-D12. (268 aa)
	Hoxd13	Homeobox protein Hox-D13. (204 aa)
	Lnpk	Protein lunapark. (350 aa)
	I79_005573	Secreted frizzled-related protein 2. (268 aa)
	Sall1	Sal-like protein 1. (1294 aa)
	I79_006225	Sonic hedgehog protein. (226 aa)
	I79_006254	Bone morphogenetic protein 4. (406 aa)
	I79_006693	Intraflagellar transport protein 88-like. (533 aa)
	Tbc1d32	Uncharacterized protein C6orf170. (336 aa)
	I79_006700	Uncharacterized protein C6orf170. (90 aa)
	I79_006701	Uncharacterized protein C6orf170-like. (356 aa)
	Hdac1	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
	I79_006923	Histone deacetylase 1. (235 aa)
	I79_006924	Histone deacetylase 1. (188 aa)
	Ctnnb1	Catenin beta-1. (781 aa)
	Tbx2	T-box transcription factor TBX2. (234 aa)
	I79_007328	Histone deacetylase 2. (91 aa)
	I79_007329	Histone deacetylase 1. (250 aa)
	I79_007641	Low-density lipoprotein receptor-related protein 6. (543 aa)
	Lrp6	Low-density lipoprotein receptor-related protein 6. (565 aa)
	Ift140	Intraflagellar transport protein 140-like. (1462 aa)
	Bpnt2	Inositol monophosphatase 3. (167 aa)
	Hoxa11	Homeobox protein Hox-A11. (250 aa)
	Osr1	Protein odd-skipped-related 1. (266 aa)
	Wdpcp	WD repeat-containing protein C2orf86-like. (596 aa)
	I79_009343	N-myc proto-oncogene protein. (316 aa)
	Hdac2	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
	Mks1	Meckel syndrome type 1 protein-like. (561 aa)
	I79_010954	Uncharacterized protein C5orf42. (531 aa)
	Cplane1	Uncharacterized protein C5orf42. (563 aa)
	I79_011377	Grainyhead-like protein 2-like. (522 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B9d1	Chst11	G3GVJ4	G3HQL4	B9 domain-containing protein 1.	Carbohydrate sulfotransferase.	0.502
B9d1	I79_006693	G3GVJ4	G3H8J1	B9 domain-containing protein 1.	Intraflagellar transport protein 88-like.	0.471
B9d1	Ift122	G3GVJ4	G3HVL8	B9 domain-containing protein 1.	Intraflagellar transport protein 122-like.	0.401
B9d1	Ift140	G3GVJ4	G3HBX9	B9 domain-containing protein 1.	Intraflagellar transport protein 140-like.	0.473
B9d1	Mks1	G3GVJ4	G3HJ74	B9 domain-containing protein 1.	Meckel syndrome type 1 protein-like.	0.930
B9d1	Tmem231	G3GVJ4	G3I4N6	B9 domain-containing protein 1.	UPF0513 transmembrane protein.	0.968
Bpnt2	Tmem231	G3HD63	G3I4N6	Inositol monophosphatase 3.	UPF0513 transmembrane protein.	0.560
C2cd3	I79_006693	G3I9W1	G3H8J1	C2 domain-containing protein 3.	Intraflagellar transport protein 88-like.	0.578
C2cd3	Tulp3	G3I9W1	G3GUJ0	C2 domain-containing protein 3.	Tubby-like protein; Belongs to the TUB family.	0.462
Chst11	B9d1	G3HQL4	G3GVJ4	Carbohydrate sulfotransferase.	B9 domain-containing protein 1.	0.502
Cplane1	I79_010954	G3HJV3	G3HJV2	Uncharacterized protein C5orf42.	Uncharacterized protein C5orf42.	0.813
Ctnnb1	Gja1	G3H996	Q80Z93	Catenin beta-1.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.642
Ctnnb1	Hdac1	G3H996	G3H942	Catenin beta-1.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.622
Ctnnb1	Hdac2	G3H996	G3HHV8	Catenin beta-1.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.624
Ctnnb1	I79_000801	G3H996	G3GT28	Catenin beta-1.	Histone deacetylase 1.	0.622
Ctnnb1	I79_005573	G3H996	G3H5J1	Catenin beta-1.	Secreted frizzled-related protein 2.	0.590
Ctnnb1	I79_006225	G3H996	G3H796	Catenin beta-1.	Sonic hedgehog protein.	0.553
Ctnnb1	I79_006254	G3H996	G3H7C4	Catenin beta-1.	Bone morphogenetic protein 4.	0.448
Ctnnb1	I79_006923	G3H996	G3H959	Catenin beta-1.	Histone deacetylase 1.	0.622
Ctnnb1	I79_006924	G3H996	G3H960	Catenin beta-1.	Histone deacetylase 1.	0.622