STRINGSTRING
I79_009961 I79_009961 I79_009874 I79_009874 Siah2 Siah2 Bcl2l1 Bcl2l1 Tnfsf14 Tnfsf14 I79_007335 I79_007335 I79_007261 I79_007261 Mmp9 Mmp9 Skor1 Skor1 Gpx1 Gpx1 Prdx3 Prdx3 Cdkn2d Cdkn2d Rps6ka3 Rps6ka3 Igf1 Igf1 I79_005573 I79_005573 Fnip1 Fnip1 CgPICR_001424 CgPICR_001424 I79_005037 I79_005037 Sh3rf1 Sh3rf1 Akt1 Akt1 Cryab Cryab Rnf34 Rnf34 I79_003373 I79_003373 I79_002785 I79_002785 Src Src Mical1 Mical1 I79_002510 I79_002510 I79_002266 I79_002266 I79_002265 I79_002265 I79_002263 I79_002263 Ptgs2 Ptgs2 Ints1 Ints1 I79_001482 I79_001482 Nle1 Nle1 Rffl Rffl Pak2 Pak2 Dpep1 Dpep1 CgPICR_003973 CgPICR_003973 Arl6ip1 Arl6ip1 Arrb1 Arrb1 I79_023773 I79_023773 H671_3g9632 H671_3g9632 Bcl2l12 Bcl2l12 I79_021155 I79_021155 Klf4 Klf4 I79_020464 I79_020464 I79_020212 I79_020212 Xiap Xiap HSPA5 HSPA5 Gas6 Gas6 Triap1 Triap1 Lamp3 Lamp3 I79_017991 I79_017991 I79_016664 I79_016664 Tnf Tnf I79_016276 I79_016276 Rps6ka1 Rps6ka1 Sfn Sfn Adora2a Adora2a Vil1 Vil1 Usp47 Usp47 I79_015181 I79_015181 Mrtfa Mrtfa I79_015109 I79_015109 Cflar Cflar I79_013579 I79_013579 I79_013578 I79_013578 I79_013577 I79_013577 Hgf Hgf Akt2 Akt2 Aqp1 Aqp1 Fabp1 Fabp1 I79_010620 I79_010620 I79_010559 I79_010559 Herpud1 Herpud1 I79_010470 I79_010470 I79_010330 I79_010330 Thbs1 Thbs1 I79_010137 I79_010137
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_009961Uncharacterized protein C9orf82-like. (230 aa)
I79_009874Baculoviral IAP repeat-containing protein 7. (196 aa)
Siah2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (195 aa)
Bcl2l1Bcl-2-like protein 1. (233 aa)
Tnfsf14Tumor necrosis factor ligand superfamily member 14. (238 aa)
I79_007335DnaJ-like subfamily B member 6-B. (138 aa)
I79_007261NADPH--cytochrome P450 reductase. (522 aa)
Mmp9Matrix metalloproteinase-9. (710 aa)
Skor1Dual specificity mitogen-activated protein kinase kinase 5. (719 aa)
Gpx1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
Prdx3Thioredoxin-dependent peroxide reductase, mitochondrial. (257 aa)
Cdkn2dCyclin-dependent kinase 4 inhibitor D. (166 aa)
Rps6ka3Non-specific serine/threonine protein kinase. (712 aa)
Igf1Insulin-like growth factor I. (75 aa)
I79_005573Secreted frizzled-related protein 2. (268 aa)
Fnip1Folliculin-interacting protein 1. (1435 aa)
CgPICR_001424Oxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family. (126 aa)
I79_005037Oxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family. (126 aa)
Sh3rf1Putative E3 ubiquitin-protein ligase SH3RF1. (885 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CryabAlpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
Rnf34E3 ubiquitin-protein ligase RNF34. (378 aa)
I79_003373Fas apoptotic inhibitory molecule 3. (326 aa)
I79_002785Beta-arrestin-2. (65 aa)
SrcTyrosine-protein kinase. (536 aa)
Mical1NEDD9-interacting protein with calponin-likey and LIM domains. (345 aa)
I79_002510NEDD9-interacting protein with calponin-likey and LIM domains. (165 aa)
I79_002266Serpin B9; Belongs to the serpin family. (262 aa)
I79_002265Serpin B9; Belongs to the serpin family. (375 aa)
I79_002263Serpin B9; Belongs to the serpin family. (339 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
Ints1Integrator complex subunit 1. (1521 aa)
I79_001482Baculoviral IAP repeat-containing protein 3. (601 aa)
Nle1Notchless protein-like 1. (297 aa)
RfflE3 ubiquitin-protein ligase rififylin. (377 aa)
Pak2Non-specific serine/threonine protein kinase. (524 aa)
Dpep1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (410 aa)
CgPICR_003973Hepatitis B virus X-interacting protein-like. (133 aa)
Arl6ip1ADP-ribosylation factor-like protein 6-interacting protein 1. (203 aa)
Arrb1Beta-arrestin-1. (422 aa)
I79_023773Nuclear receptor subfamily 4 group A member 1. (924 aa)
H671_3g9632Baculoviral IAP repeat-containing protein 5. (69 aa)
Bcl2l12Bcl-2-like protein 12. (255 aa)
I79_021155Paired box protein Pax-2. (503 aa)
Klf4Krueppel-like factor 4. (474 aa)
I79_020464Interleukin-9 receptor. (320 aa)
I79_020212DnaJ-like subfamily B member 6. (361 aa)
XiapBaculoviral IAP repeat-containing protein 4. (441 aa)
HSPA5Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] (654 aa)
Gas6Growth arrest-specific protein 6. (684 aa)
Triap1TP53-regulated inhibitor of apoptosis 1. (79 aa)
Lamp3Lysosome-associated membrane glycoprotein 3. (285 aa)
I79_017991Lysosome-associated membrane glycoprotein 3. (91 aa)
I79_016664PIH1 domain-containing protein 1. (280 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
I79_016276Urokinase plasminogen activator surface receptor. (186 aa)
Rps6ka1Ribosomal protein S6 kinase. (743 aa)
Sfn14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
Adora2aAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (408 aa)
Vil1Villin-1. (827 aa)
Usp47Ubiquitin carboxyl-terminal hydrolase 47. (754 aa)
I79_01518114-3-3 protein sigma; Belongs to the 14-3-3 family. (249 aa)
MrtfaMKL/myocardin-like protein 1. (1047 aa)
I79_015109Interleukin-6. (174 aa)
CflarCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (484 aa)
I79_013579Baculoviral IAP repeat-containing protein 1a. (197 aa)
I79_013578Baculoviral IAP repeat-containing protein 1a. (291 aa)
I79_013577Baculoviral IAP repeat-containing protein 1b. (199 aa)
HgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
Aqp1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
Fabp1Fatty acid-binding protein, liver. (149 aa)
I79_010620Alpha-synuclein; Belongs to the synuclein family. (166 aa)
I79_010559Baculoviral IAP repeat-containing protein 1b. (968 aa)
Herpud1Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein. (506 aa)
I79_010470Metallothionein-3; Belongs to the metallothionein superfamily. Type 1 family. (108 aa)
I79_010330Hepatocyte nuclear factor 1-alpha. (668 aa)
Thbs1Thrombospondin-1. (533 aa)
I79_010137Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (262 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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