STRINGSTRING
I79_015916 I79_015916 I79_015980 I79_015980 Adipoq Adipoq Hif1a Hif1a Foxo1 Foxo1 Pth Pth Hnf4a Hnf4a Nnmt Nnmt Erfe Erfe Serpina12 Serpina12 Pdgfb Pdgfb Ppp4r3a Ppp4r3a Ppp1ca Ppp1ca C1qtnf12 C1qtnf12 I79_018194 I79_018194 Ep300 Ep300 Ap2a1 Ap2a1 Sik1 Sik1 Tgfb1 Tgfb1 I79_020647 I79_020647 Enpp1 Enpp1 I79_020783 I79_020783 I79_021564 I79_021564 Wdr5 Wdr5 I79_021679 I79_021679 Irs1 Irs1 Fam3c Fam3c Mtor Mtor I79_022343 I79_022343 I79_022390 I79_022390 Ppara Ppara P2ry6 P2ry6 Znf692 Znf692 Ddb1 Ddb1 Tcf7l2 Tcf7l2 Irs2 Irs2 Arpp19 Arpp19 I79_024892 I79_024892 I79_025482 I79_025482 Nfkb1 Nfkb1 I79_025689 I79_025689 Smpd3 Smpd3 Has2 Has2 I79_025944 I79_025944 I79_009691 I79_009691 I79_009790 I79_009790 Ntsr1 Ntsr1 I79_010073 I79_010073 slc25B4 slc25B4 CgPICR_005189 CgPICR_005189 Plcd1 Plcd1 Usp7 Usp7 Acadm Acadm I79_001927 I79_001927 Ppp1r3a Ppp1r3a Ppp1cb Ppp1cb I79_002406 I79_002406 Soga1 Soga1 Dyrk2 Dyrk2 Lep Lep Ppp1r3b Ppp1r3b Sesn2 Sesn2 Ptafr Ptafr Akt1 Akt1 Ppp1r3c Ppp1r3c Nln Nln I79_005309 I79_005309 LHCGR LHCGR Igf1 Igf1 I79_006470 I79_006470 I79_006650 I79_006650 Mst1 Mst1 Sirt1 Sirt1 Pgp Pgp I79_007993 I79_007993 Clk2 Clk2 C1qtnf2 C1qtnf2 Dgkq Dgkq Plek Plek Nr3c1 Nr3c1 Stk11 Stk11 I79_009443 I79_009443 I79_010620 I79_010620 Ranbp2 Ranbp2 Cltc Cltc I79_010863 I79_010863 Pdk2 Pdk2 Ppp4r3b Ppp4r3b C1qtnf3 C1qtnf3 I79_011304 I79_011304 I79_011333 I79_011333 P2ry1 P2ry1 Kat2a Kat2a Gck Gck Ppp1r3f Ppp1r3f I79_012336 I79_012336 Akt2 Akt2 Cry1 Cry1 I79_012722 I79_012722 I79_013328 I79_013328 I79_013329 I79_013329 Epm2aip1 Epm2aip1 Inpp5k Inpp5k Gper1 Gper1 Dgat2 Dgat2 I79_015045 I79_015045 I79_015109 I79_015109 Gpt Gpt Insr Insr I79_015895 I79_015895
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_015916Insulin-like growth factor II. (155 aa)
I79_015980Leptin receptor. (533 aa)
AdipoqAdiponectin. (248 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
Foxo1Forkhead box protein O1. (469 aa)
PthParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)
Hnf4aHepatocyte nuclear factor 4-alpha. (464 aa)
NnmtNicotinamide N-methyltransferase. (265 aa)
ErfeProtein FAM132B. (344 aa)
Serpina12Serpin A12; Belongs to the serpin family. (414 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
Ppp4r3aSerine/threonine-protein phosphatase 4 regulatory subunit 3A. (400 aa)
Ppp1caSerine/threonine-protein phosphatase PP1-alpha catalytic subunit. (148 aa)
C1qtnf12Protein FAM132A. (61 aa)
I79_018194Protein FAM132A. (127 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
Ap2a1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (946 aa)
Sik1Serine/threonine-protein kinase SIK1. (729 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
I79_020647Protein FAM48A. (330 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
Wdr5WD repeat-containing protein 5. (334 aa)
I79_021679POU domain protein. (218 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
Fam3cProtein FAM3C. (227 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
I79_022343UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1444 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
P2ry6p2Y purinoceptor 6. (328 aa)
Znf692Zinc finger protein 692. (222 aa)
Ddb1DNA damage-binding protein 1. (1140 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
Irs2Insulin receptor substrate 2. (465 aa)
Arpp19cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (112 aa)
I79_024892Fructose-1,6-bisphosphatase 1. (66 aa)
I79_025482Nuclear factor NF-kappa-B p105 subunit. (144 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (509 aa)
I79_025689Epididymal-specific lipocalin-13; Belongs to the calycin superfamily. Lipocalin family. (158 aa)
Smpd3Sphingomyelin phosphodiesterase 3. (446 aa)
Has2Hyaluronan synthase 2. (337 aa)
I79_025944Hyaluronan synthase 2. (151 aa)
I79_009691Growth factor receptor-bound protein 10. (518 aa)
I79_009790MAS proto-oncogene; Belongs to the G-protein coupled receptor 1 family. (324 aa)
Ntsr1Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
I79_010073Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (511 aa)
slc25B4UDP-xylose and UDP-N-acetylglucosamine transporter. (331 aa)
CgPICR_005189cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (96 aa)
Plcd1Phosphoinositide phospholipase C. (782 aa)
Usp7Ubiquitin carboxyl-terminal hydrolase 7. (82 aa)
AcadmMedium-chain specific acyl-CoA dehydrogenase, mitochondrial. (96 aa)
I79_001927Protein phosphatase 1 regulatory subunit 3A. (263 aa)
Ppp1r3aProtein phosphatase 1 regulatory subunit 3A. (692 aa)
Ppp1cbSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (299 aa)
I79_002406NAD-dependent deacetylase sirtuin-7. (306 aa)
Soga1Uncharacterized protein C20orf117. (1897 aa)
Dyrk2Dual specificity tyrosine-phosphorylation-regulated kinase 2. (528 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Ppp1r3bProtein phosphatase 1 regulatory subunit. (284 aa)
Sesn2Sestrin-2. (480 aa)
PtafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Ppp1r3cProtein phosphatase 1 regulatory subunit. (312 aa)
NlnNeurolysin, mitochondrial. (704 aa)
I79_005309PAS domain-containing serine/threonine-protein kinase. (1162 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (688 aa)
Igf1Insulin-like growth factor I. (75 aa)
I79_006470Natural killer cell receptor 2B4. (280 aa)
I79_006650Hepatocyte growth factor-like protein. (93 aa)
Mst1Hepatocyte growth factor-like protein. (88 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
PgpPhosphoglycolate phosphatase. (617 aa)
I79_007993Dual specificity protein kinase CLK2. (137 aa)
Clk2Dual specificity protein kinase CLK2. (109 aa)
C1qtnf2Complement C1q tumor necrosis factor-related protein 2. (285 aa)
DgkqDiacylglycerol kinase. (491 aa)
PlekPleckstrin. (327 aa)
Nr3c1Glucocorticoid receptor. (748 aa)
Stk11Serine/threonine-protein kinase 11. (505 aa)
I79_009443Steroid hormone receptor ERR2. (475 aa)
I79_010620Alpha-synuclein; Belongs to the synuclein family. (166 aa)
Ranbp2E3 SUMO-protein ligase RanBP2. (3068 aa)
CltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1960 aa)
I79_010863Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family. (533 aa)
Pdk2Protein-serine/threonine kinase. (407 aa)
Ppp4r3bSerine/threonine-protein phosphatase 4 regulatory subunit 3B. (1364 aa)
C1qtnf3Complement C1q tumor necrosis factor-related protein 3. (319 aa)
I79_011304Parathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (626 aa)
I79_011333Sphingomyelin phosphodiesterase 3. (410 aa)
P2ry1p2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
Kat2aHistone acetyltransferase KAT2A. (663 aa)
GckPhosphotransferase. (465 aa)
Ppp1r3fProtein phosphatase 1 regulatory subunit 3F. (477 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
Cry1Cryptochrome-1. (428 aa)
I79_012722Major urinary protein 5; Belongs to the calycin superfamily. Lipocalin family. (153 aa)
I79_013328Glycine N-methyltransferase. (71 aa)
I79_013329Glycine N-methyltransferase. (69 aa)
Epm2aip1EPM2A-interacting protein 1. (606 aa)
Inpp5kInositol polyphosphate 5-phosphatase K. (451 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
Dgat2Diacylglycerol O-acyltransferase 2. (388 aa)
I79_015045MAS proto-oncogene. (172 aa)
I79_015109Interleukin-6. (174 aa)
GptAlanine aminotransferase 1. (481 aa)
InsrInsulin receptor. (114 aa)
I79_015895Sorbin and SH3 domain-containing protein 1. (852 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (20%) [HD]