STRINGSTRING
Ntf3 Ntf3 I79_000697 I79_000697 ilk ilk Psen1 Psen1 I79_012336 I79_012336 I79_012384 I79_012384 I79_012394 I79_012394 Maged1 Maged1 Pdcd10 Pdcd10 Ajuba Ajuba Map2k7 Map2k7 I79_013660 I79_013660 Pdgfrb Pdgfrb Irak1 Irak1 Tdgf1 Tdgf1 Fzd5 Fzd5 Map3k12 Map3k12 Insr Insr Dab2ip Dab2ip I79_015983 I79_015983 I79_016051 I79_016051 Pdgfd Pdgfd Ager Ager I79_016423 I79_016423 Tnf Tnf I79_016567 I79_016567 Tlr4 Tlr4 IL1B IL1B Fzd10 Fzd10 Tab1 Tab1 Pdgfb Pdgfb Dvl3 Dvl3 I79_017859 I79_017859 Hras Hras Drd4 Drd4 I79_018131 I79_018131 Htr2a Htr2a I79_018306 I79_018306 CgPICR_011244 CgPICR_011244 Tgfa Tgfa Map4k2 Map4k2 Adra2a Adra2a I79_019934 I79_019934 I79_020009 I79_020009 H671_5g14804 H671_5g14804 Nox4 Nox4 Tgfb1 Tgfb1 I79_020594 I79_020594 Adam8 Adam8 Fgd4 Fgd4 I79_020968 I79_020968 I79_020969 I79_020969 I79_021125 I79_021125 I79_021564 I79_021564 Ghr Ghr Rps3 Rps3 I79_021789 I79_021789 Map3k11 Map3k11 I79_021835 I79_021835 I79_021836 I79_021836 I79_021837 I79_021837 Fzd4 Fzd4 Iqgap1 Iqgap1 Traf2 Traf2 Il1rn Il1rn Ntrk3 Ntrk3 Csk Csk I79_024271 I79_024271 I79_024744 I79_024744 Pak1 Pak1 Kit Kit Ccl19 Ccl19 App App Arhgef5 Arhgef5 Map3k13 Map3k13 Fgd2 Fgd2 I79_011154 I79_011154 Kitlg Kitlg Syk Syk Map3k1 Map3k1 Rasgrp1 Rasgrp1 Thbs1 Thbs1 I79_010159 I79_010159 Robo1 Robo1 Tnfsf11 Tnfsf11 I79_009795 I79_009795 Ptpn1 Ptpn1 Fgf1 Fgf1 I79_008941 I79_008941 Axin1 Axin1 Mapk8ip3 Mapk8ip3 I79_007935 I79_007935 Mef2c Mef2c Il34 Il34 Cd40 Cd40 Skor1 Skor1 Dusp19 Dusp19 Mst1r Mst1r I79_006547 I79_006547 Vangl2 Vangl2 Dkk1 Dkk1 Nod2 Nod2 I79_004922 I79_004922 Erp29 Erp29 I79_004285 I79_004285 I79_004035 I79_004035 I79_004031 I79_004031 Edn1 Edn1 Tlr9 Tlr9 I79_003212 I79_003212 Gpr39 Gpr39 Traf6 Traf6 Phf23 Phf23 I79_002696 I79_002696 Pik3r5 Pik3r5 Src Src Ezh2 Ezh2 Edn3 Edn3 I79_002099 I79_002099 Prkcd Prkcd Wnt5a Wnt5a Taok3 Taok3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ntf3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (258 aa)
I79_000697Mitogen-activated protein kinase kinase kinase 7. (287 aa)
ilkIntegrin-linked protein kinase. (452 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
I79_012384Leukocyte common antigen. (962 aa)
I79_012394Mitogen-activated protein kinase kinase kinase 10. (594 aa)
Maged1Melanoma-associated antigen D1-like protein. (776 aa)
Pdcd10Programmed cell death protein 10. (210 aa)
AjubaProtein ajuba. (214 aa)
Map2k7Dual specificity mitogen-activated protein kinase kinase 7. (391 aa)
I79_013660Beta-type platelet-derived growth factor receptor. (454 aa)
PdgfrbBeta-type platelet-derived growth factor receptor. (528 aa)
Irak1Interleukin-1 receptor-associated kinase 1. (494 aa)
Tdgf1Receptor-transporting protein 3. (313 aa)
Fzd5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (616 aa)
Map3k12Mitogen-activated protein kinase kinase kinase 12. (274 aa)
InsrInsulin receptor. (114 aa)
Dab2ipDisabled-like 2-interacting protein. (1065 aa)
I79_015983Teneurin-1. (1750 aa)
I79_016051Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (777 aa)
PdgfdPlatelet-derived growth factor D. (253 aa)
AgerAdvanced glycosylation end product-specific receptor. (334 aa)
I79_016423Advanced glycosylation end product-specific receptor. (65 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
I79_016567Zinc finger E-box-binding homeobox 2. (1282 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Fzd10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (488 aa)
Tab1Mitogen-activated protein kinase kinase kinase 7-interacting protein 1. (336 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
Dvl3Segment polarity protein dishevelled-like DVL-3. (503 aa)
I79_017859A-kinase anchor protein 13. (2703 aa)
HrasGTPase HRas-like protein. (189 aa)
Drd4D(4) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (387 aa)
I79_0181315-hydroxytryptamine receptor 2A; Belongs to the G-protein coupled receptor 1 family. (237 aa)
Htr2a5-hydroxytryptamine receptor 2A. (264 aa)
I79_018306Ephrin type-A receptor 4. (932 aa)
CgPICR_01124440S ribosomal protein S3. (94 aa)
TgfaProtransforming growth factor alpha. (211 aa)
Map4k2Mitogen-activated protein kinase kinase kinase kinase 2. (259 aa)
Adra2aAlpha-2A adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (418 aa)
I79_019934Mitogen-activated protein kinase kinase kinase 7-interacting protein 1. (263 aa)
I79_020009Phosphodiesterase. (597 aa)
H671_5g14804Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1012 aa)
Nox4NADPH oxidase 4. (130 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
I79_020594Tumor protein D53. (162 aa)
Adam8Disintegrin and metalloproteinase domain-containing protein 8. (936 aa)
Fgd4FYVE, RhoGEF and PH domain-containing protein 4. (665 aa)
I79_020968Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (104 aa)
I79_020969Fibroblast growth factor 18. (85 aa)
I79_021125Epigen. (135 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
GhrGrowth hormone receptor. (345 aa)
Rps340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (117 aa)
I79_021789NT-3 growth factor receptor. (389 aa)
Map3k11Mitogen-activated protein kinase kinase kinase. (850 aa)
I79_021835Leucine-rich repeat serine/threonine-protein kinase 2. (354 aa)
I79_021836Leucine-rich repeat serine/threonine-protein kinase 2. (1184 aa)
I79_021837Leucine-rich repeat serine/threonine-protein kinase 2. (441 aa)
Fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
Iqgap1Ras GTPase-activating-like protein IQGAP1. (1675 aa)
Traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
Il1rnInterleukin-1. (157 aa)
Ntrk3Tyrosine-protein kinase receptor. (226 aa)
CskTyrosine-protein kinase. (450 aa)
I79_024271NT-3 growth factor receptor. (114 aa)
I79_0247445-hydroxytryptamine receptor 2B. (407 aa)
Pak1Serine/threonine-protein kinase PAK 1. (325 aa)
KitMast/stem cell growth factor receptor. (452 aa)
Ccl19C-C motif chemokine. (117 aa)
AppAmyloid beta A4 protein. (433 aa)
Arhgef5Rho guanine nucleotide exchange factor 5. (1561 aa)
Map3k13Mitogen-activated protein kinase kinase kinase 13. (431 aa)
Fgd2FYVE, RhoGEF and PH domain-containing protein 2. (250 aa)
I79_011154FYVE, RhoGEF and PH domain-containing protein 2. (359 aa)
KitlgKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
SykTyrosine-protein kinase. (611 aa)
Map3k1Mitogen-activated protein kinase kinase kinase 1. (1340 aa)
Rasgrp1RAS guanyl-releasing protein 1. (787 aa)
Thbs1Thrombospondin-1. (533 aa)
I79_010159Roundabout-like 1. (1362 aa)
Robo1Roundabout-like 1. (129 aa)
Tnfsf11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (199 aa)
I79_009795Mitogen-activated protein kinase kinase kinase 4. (1824 aa)
Ptpn1Tyrosine-protein phosphatase non-receptor type 1. (335 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
Axin1Axin-1. (863 aa)
Mapk8ip3C-jun-amino-terminal kinase-interacting protein 3. (1073 aa)
I79_007935C-jun-amino-terminal kinase-interacting protein 3. (95 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Il34Interleukin-34. (201 aa)
Cd40Tumor necrosis factor receptor superfamily member 5. (118 aa)
Skor1Dual specificity mitogen-activated protein kinase kinase 5. (719 aa)
Dusp19Dual specificity protein phosphatase 19-like protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (220 aa)
Mst1rMacrophage-stimulating protein receptor. (1382 aa)
I79_006547Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (311 aa)
Vangl2Vang-like protein. (521 aa)
Dkk1Dickkopf-related protein 1. (269 aa)
Nod2Nucleotide-binding oligomerization domain-containing protein 2. (989 aa)
I79_004922SAM and SH3 domain-containing protein 1. (999 aa)
Erp29Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (260 aa)
I79_004285p2X purinoceptor 7. (805 aa)
I79_004035Disintegrin and metalloproteinase domain-containing protein 9. (1196 aa)
I79_004031Fibroblast growth factor receptor. (731 aa)
Edn1Endothelin-1. (202 aa)
Tlr9Toll-like receptor 9. (1239 aa)
I79_003212G-protein coupled receptor 39. (151 aa)
Gpr39G-protein coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (289 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
Phf23Segment polarity protein dishevelled-like DVL-2. (697 aa)
I79_002696Phosphoinositide 3-kinase regulatory subunit 6. (395 aa)
Pik3r5Phosphoinositide 3-kinase regulatory subunit 5. (148 aa)
SrcTyrosine-protein kinase. (536 aa)
Ezh2Histone-lysine N-methyltransferase EZH2. (746 aa)
Edn3Endothelin-3. (274 aa)
I79_002099Vascular endothelial growth factor receptor 1. (115 aa)
PrkcdNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (437 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Taok3Serine/threonine-protein kinase TAO3. (898 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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